A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection [PDF]
Frontiers in Microbiology, 2019 Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng +3 more
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Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography [PDF]
Nature CommunicationsBorna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon)
Arnt Ebinger +36 more
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Borna Disease Virus 1 as Cause of Fatal Meningoencephalomyelitis in Wild Hedgehogs, Germany, 2022–2025 [PDF]
Emerging Infectious DiseasesBorna disease virus 1 (BoDV-1) causes encephalitis with a fatality rate of >90% in domestic mammals and humans. Currently, the bicolored white-toothed shrew is the only known reservoir host. We report BoDV-1 infections in 15 wild European hedgehogs from
Effrosyni Michelakaki +15 more
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Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539 [PDF]
Viruses, 2022 Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated.
Liv Bode +3 more
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Nucleocytoplasmic Shuttling of Viral Proteins in Borna Disease Virus Infection
Viruses, 2013 Nuclear import and export of viral RNA and proteins are critical to the replication cycle of viruses that replicate in the nucleus. Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that belongs to the order Mononegavirales.
Tomoyuki Honda, Keizo Tomonaga
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Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]
npj VirusesMammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda +5 more
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Infections of horses and shrews with Bornaviruses in Upper Austria: a novel endemic area of Borna disease [PDF]
Emerging Microbes and Infections, 2017 Borna disease, a lethal infection with Borna disease virus-1 (BoDV-1), was diagnosed in four horses from Upper Austria in 2015 and 2016. All cases occurred in winter (two cases in February 2015 and two cases in December 2016), and the maximal distance of
Herbert Weissenböck +6 more
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Increasing evidence of human infections by the neurotropic Borna disease virus 1 (BoDV-1) [PDF]
Virulence, 2023 Michaela Cain, Hinh Ly
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Detection of Borna Disease Virus (BDV) in Patients with First Episode of Schizophrenia [PDF]
Iranian Journal of Psychiatry, 2016 Objective: Schizophrenia is a complex widespread neuropsychiatric disorder. This illness encompasses a complex debilitating mental disorder causing illusion, delusion, disturbed relationship, low motivation and decline of emotion.
Hasan Soltani +4 more
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Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Borna disease virus is a neurotropic, non-cytolytic virus that has been widely employed in neuroscientific research. Previous studies have revealed that metabolic perturbations are associated with Borna disease viral infection.
Rongzhong Huang +12 more
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