Results 11 to 20 of about 4,870,458 (194)

Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography [PDF]

Nature Communications
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon)
Arnt Ebinger, Pauline D. Santos, Florian Pfaff, Ralf Dürrwald, Jolanta Kolodziejek, Kore Schlottau, Viktoria Ruf, Friederike Liesche-Starnecker, Armin Ensser, Klaus Korn, Reiner Ulrich, Jenny Fürstenau, Kaspar Matiasek, Florian Hansmann, Torsten Seuberlich, Daniel Nobach, Matthias Müller, Antonie Neubauer-Juric, Marcel Suchowski, Markus Bauswein, Hans-Helmut Niller, Barbara Schmidt, Dennis Tappe, Daniel Cadar, Timo Homeier-Bachmann, Viola C. Haring, Kirsten Pörtner, Christina Frank, Lars Mundhenk, Bernd Hoffmann, Jochen Herms, Wolfgang Baumgärtner, Norbert Nowotny, Jürgen Schlegel, Rainer G. Ulrich, Martin Beer, Dennis Rubbenstroth   +36 more
doaj   +3 more sources

Shrews as Reservoir Hosts of Borna Disease Virus

Emerging Infectious Diseases, 2006
Borna disease virus (BDV) is the causative agent of severe T-cell–mediated meningoencephalitis in horses, sheep, and other animal species in central Europe.
Monika Hilbe, Romana Herrsche, Jolanta Kolodziejek, Norbert Nowotny, Kati Zlinszky, Felix Ehrensperger   +5 more
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Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report [PDF]

BMC Infectious Diseases, 2021
Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe, Kirsten Pörtner, Christina Frank, Hendrik Wilking, Arnt Ebinger, Christiane Herden, Christoph Schulze, Birgit Muntau, Petra Eggert, Petra Allartz, Gerlind Schuldt, Jonas Schmidt-Chanasit, Martin Beer, Dennis Rubbenstroth   +13 more
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Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1 [PDF]

Viruses, 2022
Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
doaj   +2 more sources

Healthcare-associated exposure to Borna disease virus 1 (BoDV-1) [PDF]

Journal of Occupational Medicine and Toxicology, 2022
The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein, Switzerland and Austria.
Judith Reinmiedl, Heiko Schulz, Viktoria C. Ruf, Moritz R. Hernandez Petzsche, Jürgen Rissland, Dennis Tappe   +5 more
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Molecular epidemiology of human Borna disease virus 1 infection revisited [PDF]

Emerging Microbes and Infections, 2022
Borna disease virus 1 (BoDV-1) strains attracted public interest by recently reported rare fatal encephalitis cases in Germany. Previously, human BoDV-1 infection was suggested to contribute to psychiatric diseases.
Liv Bode, Yujie Guo, Peng Xie
doaj   +2 more sources

Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells. [PDF]

PLoS ONE, 2012
BACKGROUND: Borna disease virus is a neurotropic, non-cytolytic virus that has been widely employed in neuroscientific research. Previous studies have revealed that metabolic perturbations are associated with Borna disease viral infection.
Rongzhong Huang, Hongchang Gao, Liang Zhang, Jianmin Jia, Xia Liu, Peng Zheng, Lihua Ma, Wenjuan Li, Jing Deng, Xiao Wang, Liu Yang, Mingju Wang, Peng Xie   +12 more
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Is vaccination a feasible public health strategy against fatal Borna disease virus 1 (BoDV-1) encephalitis? An epidemiological perspective. [PDF]

PLoS Pathogens
Human Borna disease virus 1 (BoDV-1) encephalitis is characterized by rapid clinical progression, an absence of a causal therapy and an extremely high case fatality rate.
Kirsten Pörtner, Christina Frank, Hendrik Wilking, Klaus Stark, Christiane Herden, Martin Beer, Dennis Rubbenstroth, Dennis Tappe   +7 more
doaj   +2 more sources

Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease [PDF]

Emerging Infectious Diseases, 2008
Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus.
Kirsi S. Honkavuori, H.L. Shivaprasad, Brent L. Williams, Phenix-Lan Quan, Mady Hornig, Craig Street, Gustavo Palacios, Stephen K. Hutchison, Monique Franca, Michael Egholm, Thomas Briese, W. Ian Lipkin   +11 more
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Vaccination against Borna Disease: Overview, Vaccine Virus Characterization and Investigation of Live and Inactivated Vaccines [PDF]

Viruses, 2022
(1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s.
Ralf Dürrwald, Jolanta Kolodziejek, Djin-Ye Oh, Sibylle Herzog, Heinrich Liebermann, Nikolaus Osterrieder, Norbert Nowotny   +6 more
doaj   +2 more sources