Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography [PDF]
Nature CommunicationsBorna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon)
Arnt Ebinger +36 more
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Shrews as Reservoir Hosts of Borna Disease Virus
Emerging Infectious Diseases, 2006 Borna disease virus (BDV) is the causative agent of severe T-cell–mediated meningoencephalitis in horses, sheep, and other animal species in central Europe.
Monika Hilbe +5 more
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Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Borna disease virus is a neurotropic, non-cytolytic virus that has been widely employed in neuroscientific research. Previous studies have revealed that metabolic perturbations are associated with Borna disease viral infection.
Rongzhong Huang +12 more
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Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease
Emerging Infectious Diseases, 2008 Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus.
Kirsi S. Honkavuori +11 more
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IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study [PDF]
Viruses, 2023 More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany.
Lisa Eidenschink +18 more
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A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection [PDF]
Frontiers in Microbiology, 2019 Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng +3 more
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Borna Disease Virus Infection in Animals and Humans
Emerging Infectious Diseases, 1997 The geographic distribution and host range of Borna disease (BD), a fatal neurologic disease of horses and sheep, are larger than previously thought.
Jürgen A. Richt +5 more
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Borna Disease Virus 1 as Cause of Fatal Meningoencephalomyelitis in Wild Hedgehogs, Germany, 2022–2025 [PDF]
Emerging Infectious DiseasesBorna disease virus 1 (BoDV-1) causes encephalitis with a fatality rate of >90% in domestic mammals and humans. Currently, the bicolored white-toothed shrew is the only known reservoir host. We report BoDV-1 infections in 15 wild European hedgehogs from
Effrosyni Michelakaki +15 more
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EFSA Journal, 2017 Borna disease has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of Borna disease to be listed, Article 9 for the categorisation of ...
EFSA Panel on Animal Health and Welfare (AHAW) +26 more
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Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539 [PDF]
Viruses, 2022 Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated.
Liv Bode +3 more
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