Results 31 to 40 of about 4,870,458 (194)
Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [PDF]
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda +5 more
doaj +2 more sources
Extreme Hyperleukocytosis in Meningococcal Bacteremia Mimicking Leukemia: A Case Report. [PDF]
Hyperleukocytosis (> 100 × 109/L) is typically associated with hematologic malignancies and is rarely reported in infection. A previously healthy 27‐year‐old man presented with acute gastrointestinal symptoms and was found to have meningococcal bacteremia complicated by thrombocytopenia, coagulopathy, and acute kidney injury.
Gorena C, Amir-Kabirian B, Chao JH.
europepmc +2 more sources
Borna disease, a lethal infection with Borna disease virus-1 (BoDV-1), was diagnosed in four horses from Upper Austria in 2015 and 2016. All cases occurred in winter (two cases in February 2015 and two cases in December 2016), and the maximal distance of
Herbert Weissenböck +6 more
doaj +3 more sources
The immunopathogenesis of Borna disease virus infection
Borna disease virus (BDV) infection represents an excellent model system to study immunopathological mechanisms based on a T cell-mediated immune reaction in the central nervous system. The single-stranded RNA Borna disease virus, a member of Bornaviridae in the order of Mononegavirale, lacks cytopathogenicity both in vitro and in vivo.
Lothar, Stitz +2 more
openaire +3 more sources
Increasing evidence of human infections by the neurotropic Borna disease virus 1 (BoDV-1) [PDF]
Michaela Cain, Hinh Ly
doaj +2 more sources
AbstractBorna disease virus (BDV) is unique amongst animal RNA viruses in its molecular biology and capacity to cause persistent, noncytolytic CNS‐infection in a wide variety of host species. Unlike other non‐segmented negative‐strand RNA animal viruses, BDV replicates in the nucleus of the host cell where splicing is employed for expression of a very ...
I, Jordan, W I, Lipkin
openaire +2 more sources
Animal Models of CNS Viral Disease: Examples from Borna Disease Virus Models
Borna disease (BD), caused by the neurotropic RNA virus, Borna Disease virus, is an affliction ranging from asymptomatic to fatal meningoencephalitis across naturally and experimentally infected warmblooded (mammalian and bird) species.
Marylou V. Solbrig
doaj +2 more sources
Pathogenesis of Borna disease [PDF]
Borna disease represents a unique model of a virus-induced immunological disease of the brain. Naturally occurring in horses and sheep, the mechanisms of pathogenesis have been studied in experimental animals, namely in the rat. Many investigations have revealed that the infection of the natural hosts principally follows the same pathogenic pathways as
L, Stitz, T, Bilzer, J A, Richt, R, Rott
openaire +2 more sources
The equine species as Trojan horse for Borna Disease Virus-1? [PDF]
J.H. van der Kolk
doaj +2 more sources
Avian Bornaviruses Escape Recognition by the Innate Immune System [PDF]
Like other pathogens that readily persist in animal hosts, members of the Bornaviridae family have evolved effective mechanisms to evade the innate immune response.
Kothlow, Sonja +18 more
core +1 more source

