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Borna disease virus and deficit schizophrenia

Acta Neuropsychiatrica, 2003
Background:It is controversial whether Borna disease virus (BDV) infects humans and causes psychiatric disorders.Objectives:The relationship between BDV infection and schizophrenia with deficit syndrome was investigated.Study design:Using the Schedule for the Deficit Syndrome, 62 schizophrenic in-patients were selected from three psychiatric hospitals.
Yong-Ku, Kim   +9 more
openaire   +2 more sources

Borna disease: virus-induced neurobehavioral disease pathogenesis

Current Opinion in Microbiology, 2001
Studies of the pathogenesis of neurobehavioral diseases following Borna disease virus infections have been increasing rapidly over the past ten years. Recent major advances have included a report of vertical transmission of the virus in its natural host, the horse, and a report of isolation of a novel variant, No/98, in that same species.
Mikhail V Pletnikov   +2 more
exaly   +3 more sources

Borna disease virus and infection in humans

Frontiers in Bioscience, 2002
Borna disease virus (BDV) is a nonsegmented, negative-, single-stranded, highly neurotropic RNA virus with noncytolytic replication in the central nervous system. This virus causes neurological and behavioral disturbances primarily in horses and sheep, in addition to a variety of other vertebrate animal species and in laboratory animal models.
Kazuyoshi, Ikuta   +3 more
openaire   +2 more sources

Molecular Biology of Borna Disease Virus

1995
Originally described in the early nineteenth century as a fatal encephalitis in horses, Borna disease (BD) has become an extraordinarily valuable model for the study of both molecular mechanisms and biological consequences of persistent virus infection in the CNS (Nicolau and Galloway 1928; Zwick 1939, this volume).
T, Briese, W I, Lipkin, J C, de la Torre
openaire   +2 more sources

Borna Disease Virus

2016
The neurotropic virus, Borna disease virus (BDV), a member of a group of nonsegmented, negative strand ribonucleic acid (RNA) viruses (order Mononegavirales), infects warm-blooded animal species. Infection among mammals may be asymptomatic, produce neurobehavioral abnormalities, or result in fatal meningoencephalitis.
openaire   +1 more source

Genetic Relationship of Borna Disease Virus Isolates

Virus Genes, 2003
The infection of humans with Boma disease virus (BDV) is still a matter of debate. In a recent publication, we described a BDV (RW98) isolated from the blood of a psychiatric patient. The RNA of this virus differed more than 5% from that of the widely used strain He/80, which was supposed to represent our laboratory virus.
Oliver, Planz   +2 more
openaire   +2 more sources

Borna disease virus interference with neuronal plasticity

Virus Research, 2005
Viruses able to infect the central nervous system (CNS) are increasingly being recognized as important factors that can cause mental diseases by interfering with neuronal plasticity. The mechanisms whereby such infections disturb brain functions are beginning to emerge.
Gonzalez-Dunia, Daniel   +3 more
openaire   +4 more sources

Borna Disease Virus

Archives of General Psychiatry, 1985
Borna disease virus is a unique neurotropic agent that appears to have a predilection for the limbic area of the brain. In some animal species, it can produce a behavioral syndrome characterized by aggressive and passive phases. This syndrome has suggested an analogy to certain human affective disorders.
J D, Amsterdam   +6 more
openaire   +2 more sources

Borna disease virus and depression

Trends in Microbiology, 2001
High amounts of circulating immune complexes of Borna disease virus correlates with severity of depression, according to Dr Liv Bode of the Robert Koch-Institut in Berlin, Germany. The virus targets limbic structure neurons and is known to cause behavioral abnormalities in animals.
openaire   +1 more source

Sequence characterization of human Borna disease virus

Virus Research, 1996
Borna disease virus (BDV) causes a central nervous system disease in several vertebrate animal species, which is manifest by behavioral abnormalities. Seroepidemiologic data suggest that BDV might infect humans, possibly being associated with certain mental disorders.
J C, de la Torre   +4 more
openaire   +2 more sources

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