Human Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany [PDF]
Emerging Microbes and Infections, 2022 In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony.
Christina Frank +14 more
doaj +3 more sources
Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1 [PDF]
Viruses, 2022 Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
doaj +2 more sources
Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report [PDF]
BMC Infectious Diseases, 2021 Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.
Dennis Tappe +13 more
doaj +2 more sources
Healthcare-associated exposure to Borna disease virus 1 (BoDV-1) [PDF]
Journal of Occupational Medicine and Toxicology, 2022 The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein, Switzerland and Austria.
Judith Reinmiedl +5 more
doaj +2 more sources
Molecular epidemiology of human Borna disease virus 1 infection revisited [PDF]
Emerging Microbes and Infections, 2022 Borna disease virus 1 (BoDV-1) strains attracted public interest by recently reported rare fatal encephalitis cases in Germany. Previously, human BoDV-1 infection was suggested to contribute to psychiatric diseases.
Liv Bode, Yujie Guo, Peng Xie
doaj +2 more sources
Is vaccination a feasible public health strategy against fatal Borna disease virus 1 (BoDV-1) encephalitis? An epidemiological perspective. [PDF]
PLoS PathogensHuman Borna disease virus 1 (BoDV-1) encephalitis is characterized by rapid clinical progression, an absence of a causal therapy and an extremely high case fatality rate.
Kirsten Pörtner +7 more
doaj +2 more sources
IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study [PDF]
Viruses, 2023 More than 40 human infections with the zoonotic Borna disease virus 1 (BoDV-1) have been reported to German health authorities from endemic regions in southern and eastern Germany.
Lisa Eidenschink +18 more
doaj +2 more sources
No evidence for European bats serving as reservoir for Borna disease virus 1 or other known mammalian orthobornaviruses [PDF]
Virology Journal, 2020 Background The majority of emerging infectious diseases are zoonotic in nature and originate from wildlife reservoirs. Borna disease, caused by Borna disease virus 1 (BoDV-1), is an infectious disease affecting mammals, but recently it has also been ...
Daniel Nobach, Christiane Herden
doaj +2 more sources
A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection [PDF]
Frontiers in Microbiology, 2019 Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng +3 more
doaj +2 more sources
Borna Disease Virus Infection in Animals and Humans [PDF]
Emerging Infectious Diseases, 1997 The geographic distribution and host range of Borna disease (BD), a fatal neurologic disease of horses and sheep, are larger than previously thought.
Jürgen A. Richt +5 more
doaj +3 more sources