Results 41 to 50 of about 2,964 (168)

Crystal Structure of the Borna Disease Virus Nucleoprotein [PDF]

Structure, 2003
Borna disease virus (BDV) causes an infection of the central nervous system in a wide range of vertebrates, which can fatally progress to an immune-mediated disease, called Borna disease. BDV is a member of the Mononegavirales, which also includes the highly infectious measles and Ebola viruses.
Rudolph, M., Kraus, I., Dickmanns, Achim, Eickmann, M., Garten, W., Ficner, R.   +5 more
openaire   +3 more sources

Adaptation of Borna Disease Virus to the Mouse

Journal of General Virology, 1984
Borna disease virus has been adapted to the mouse, which required at least three passages in rat brains. Genetic specificity as studied with five inbred mouse strains was not evident. Newborn mice inoculated intracerebrally expressed antigen in neurons and remained persistently infected, with up to 10(7) infectious units per gram of brain tissue ...
M, Kao, H, Ludwig, G, Gosztonyi
openaire   +2 more sources

The 24K protein of Borna disease virus

Journal of General Virology, 1992
Based on partial amino acid sequences obtained from tryptic peptides of the purified 24K antigen of Borna disease virus (BDV), we identified and sequenced four independent cDNA clones established from BDV-infected MDCK cells. Each of the clones encodes a polypeptide of 201 residues (Mr 22461) that differs considerably from an amino acid sequence ...
J, Thierer, H, Riehle, O, Grebenstein, T, Binz, S, Herzog, N, Thiedemann, L, Stitz, R, Rott, F, Lottspeich, H, Niemann   +9 more
openaire   +2 more sources

Mechanism of Borna Disease Virus Entry into Cells [PDF]

Journal of Virology, 1998
ABSTRACT We have investigated the entry pathway of Borna disease virus (BDV). Virus entry was assessed by detecting early viral replication and transcription. Lysosomotropic agents (ammonium chloride, chloroquine, and amantadine), as well as energy depletion, prevented BDV infection, indicating that BDV enters host cells by endocytosis and ...
D, Gonzalez-Dunia, B, Cubitt, J C, de la Torre   +2 more
openaire   +2 more sources

Insulin‐like growth factor 1 receptor correlates with verbal memory in ILAE type 2 hippocampal sclerosis

Epilepsia, Volume 67, Issue 5, Page 2572-2584, May 2026.
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz, Amauri Batista de Oliveira‐Júnior, André Fernando Garcia Cortez, Ricardo Lutzky Saute, Ricardo Silva Centeno, Joao Norberto Stávale, Mirian Salvadori Bittar Guaranha, Elza Marcia Targas Yacubian, Esper Abrão Cavalheiro, Joao Pereira Leite, Jose Eduardo Peixoto‐Santos   +10 more
wiley   +1 more source

The Neuropathogenesis of Borna Disease Virus Infections

Intervirology, 1997
The unique genetic and biological properties of this small enveloped RNA virus indicate that Borna disease virus (BDV) is an evolutionary old pathogen. It appears perfectly adapted to persist inside the limbic system, a most delicate and sensitive old area of the mammalian brain involved in the control of mood, behavior, and memory.
H, Ludwig, L, Bode
openaire   +2 more sources

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

Equine Veterinary Education, Volume 38, Issue 3, Page e119-e129, March 2026.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source

A Case of Recurrence of Severe Depressive Disorder With Flu—Neuroinflammatory Basis of Depressive Disorder

Progress in Neurology and Psychiatry, Volume 30, Issue 1, February 2026.
ABSTRACT This case highlights a relapse of major depressive disorder in an elderly man following a flu‐like illness, with clinical features and laboratory findings supporting a possible inflammatory contribution. It emphasises the relevance of the inflammatory theory of depression, especially in individuals with late‐life depression and recent immune ...
Nauman Malik, Mohamed A. Mohamed
wiley   +1 more source

The bicolored white-toothed shrew Crocidura leucodon (HERMANN 1780) is an indigenous host of mammalian Borna disease virus.

PLoS ONE, 2014
Borna disease (BD) is a sporadic neurologic disease of horses and sheep caused by mammalian Borna disease virus (BDV). Its unique epidemiological features include: limited occurrence in certain endemic regions of central Europe, yearly varying disease ...
Ralf Dürrwald, Jolanta Kolodziejek, Herbert Weissenböck, Norbert Nowotny   +3 more
doaj   +1 more source

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses

Microbiology and Immunology, Volume 70, Issue 2, Page 80-90, February 2026.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu, Takehiro Kanda, Ryo Komorizono, Madoka Sakai, Alexander Leacy, Leonardo Susta, Akiko Makino, Keizo Tomonaga   +7 more
wiley   +1 more source