Results 61 to 70 of about 3,056 (167)

Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression

Frontiers in Microbiology, 2019
Viral vectors are efficient gene delivery systems, although most of these vectors still present limitations to their practical use, such as achieving only transient transgene expression and a risk of insertional mutations.
Yusuke Yamamoto, Yusuke Yamamoto, Keizo Tomonaga, Keizo Tomonaga, Keizo Tomonaga, Tomoyuki Honda   +5 more
doaj   +1 more source

Infection burden, periodontal pathogens, and their interactive association with incident all‐cause and Alzheimer's disease dementia in a large national survey

Alzheimer's &Dementia, Volume 20, Issue 9, Page 6468-6485, September 2024.
Abstract INTRODUCTION Relationships and interplay of an infection burden (IB) and periodontal pathogens or periodontal disease (Pd) markers with Alzheimer's disease (AD) and all‐cause dementia among US adults were examined. METHODS Less than or equal to 2997 participants from the National Health and Nutrition Survey III were linked to CMS‐Medicare [≥45
May A. Beydoun, Hind A. Beydoun, Dawson W. Hedges, Lance D. Erickson, Shawn D. Gale, Jordan Weiss, Ziad W. El‐Hajj, Michele K. Evans, Alan B. Zonderman   +8 more
wiley   +1 more source

Structural comparisons of the nucleoprotein from three negative strand RNA virus families

Virology Journal, 2007
Structures of the nucleoprotein of three negative strand RNA virus families, borna disease virus, rhabdovirus and influenza A virus, are now available. Structural comparisons showed that the topology of the RNA binding region from the three proteins is ...
Tsao Jun, Zhang Xin, Green Todd J, Luo Ming, Qiu Shihong   +4 more
doaj   +1 more source

Tumour or haemorrhage?: Differential diagnosis of an unknown mass within the brain of a budgerigar (Melopsittacus undulatus) using a novel imaging pipeline

Veterinary Record Case Reports, Volume 12, Issue 3, September 2024.
Abstract We report on a previously healthy zoo specimen of an adult budgerigar (Melopsittacus undulatus, obtained with permission from Southwick's Zoo) found deceased in its enclosure. To assess cause of death and ensure the absence of an infectious neoplasia, we used an integrated multiscale brain‐imaging workflow, previously only used on mammals. The
Tatiana Vasquez, Paul M. Gignac, Peter Brewer, Maria Eugenia Leone Gold   +3 more
wiley   +1 more source

Culture as response

Ethos, Volume 52, Issue 2, Page 308-323, June 2024.
Abstract To explain cultural diversity, many theories refer to the social construction of reality. In this telling, we frame the world to make it meaningful. In my analysis of what people in Namibia and Germany know about “SARS‐Cov‐2” and “climate change,” I propose an anti‐constructivist alternative. Drawing on the work of the phenomenologist Bernhard
Michael Schnegg
wiley   +1 more source

Preliminary Studies on the Biology of Borna Disease Virus

Journal of General Virology, 1989
Borna disease virus (BDV) is an unclassified agent that causes neurological disease in a wide range of animal species and possibly in humans. The infectious nature of BDV has been long established but, despite extensive progress on the pathogenesis of the infection, the aetiological agent is still uncharacterized.
C S, Duchala, K M, Carbone, O, Narayan
openaire   +2 more sources

Bornavirus y enfermedades neuropsiquiátricas

Acta Médica Costarricense, 2006
La enfermedad producida por el virus de la enfermedad de Borna (VEB) o Borna Disease Virus (BDV), conocida como una encefalitis fatal, se ha reportado en caballos y ovejas en Europa Central, desde hace más de dos siglos.
Xinia Barrantes-Rodríguez, Sandra Silva-de la Fuente, José A Bonilla-Vargas, Fernando I Puerto   +3 more
doaj   +2 more sources

Limited availability of methods for the detection of xenotransplantation‐relevant viruses in veterinary laboratories

Xenotransplantation, Volume 31, Issue 3, May/June 2024.
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley   +1 more source

Multi-factorial Etiology of Bipolar Disorder and Schizophrenia in Iran: No Evidence of Borna Disease Virus Genome

Medical Laboratory Journal, 2018
Background and Objectives: Psychiatric disorders such as schizophrenia and bipolar disorder pose a high burden among the general population. Etiological factor(s) of such disorders remain unknown. Borna disease virus (BDV) is a neurotropic virus that has
Ameneh Arab, Alireza Mohebbi, Hamid Afshar, Abdolvahab Moradi   +3 more
doaj  

Upregulation of COX-2 and CGRP Expression in Resident Cells of the Borna Disease Virus-Infected Brain Is Dependent upon Inflammation

Neurobiology of Disease, 1999
Infection of immunocompetent adult rats with Borna disease virus (BDV) causes severe encephalitis and neural dysfunction. The expression of COX-2 and CGRP, genes previously shown to be implicated in CNS disease and peripheral inflammation, was ...
Annette M. Röhrenbeck, Michael Bette, D.Craig Hooper, Fred Nyberg, Lee E. Eiden, Bernhard Dietzschold, Eberhard Weihe   +6 more
doaj   +1 more source