Results 71 to 80 of about 2,964 (168)
Abstract To explain cultural diversity, many theories refer to the social construction of reality. In this telling, we frame the world to make it meaningful. In my analysis of what people in Namibia and Germany know about “SARS‐Cov‐2” and “climate change,” I propose an anti‐constructivist alternative. Drawing on the work of the phenomenologist Bernhard
Michael Schnegg
wiley +1 more source
Chenmeng Li,1–3,* Xiaoyan Xu,2–4,* Xiong Zhang,2–4,* Ke Cheng,2,3,* Yujie Guo,1–3 Jie Jie,1–3 Hua Guo,1–3 Yong He,1–3 Chanjuan Zhou,2,3 Siwen Gui,2,3 Xiaogang Zhong,2,3 Haiyang Wang,2–4 Peng Xie1–4 ...
Li C +12 more
doaj
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley +1 more source
Bornavirus y enfermedades neuropsiquiátricas
La enfermedad producida por el virus de la enfermedad de Borna (VEB) o Borna Disease Virus (BDV), conocida como una encefalitis fatal, se ha reportado en caballos y ovejas en Europa Central, desde hace más de dos siglos.
Xinia Barrantes-Rodríguez +3 more
doaj +2 more sources
FOXP3 deficiency, from the mechanisms of the disease to curative strategies
Summary FOXP3 gene is a key transcription factor driving immune tolerance and its deficiency causes immune dysregulation, polyendocrinopathy, enteropathy X‐linked syndrome (IPEX), a prototypic primary immune regulatory disorder (PIRD) with defective regulatory T (Treg) cells.
Simon Borna, Eric Meffre, Rosa Bacchetta
wiley +1 more source
Background and Objectives: Psychiatric disorders such as schizophrenia and bipolar disorder pose a high burden among the general population. Etiological factor(s) of such disorders remain unknown. Borna disease virus (BDV) is a neurotropic virus that has
Ameneh Arab +3 more
doaj
Infection of immunocompetent adult rats with Borna disease virus (BDV) causes severe encephalitis and neural dysfunction. The expression of COX-2 and CGRP, genes previously shown to be implicated in CNS disease and peripheral inflammation, was ...
Annette M. Röhrenbeck +6 more
doaj +1 more source
A reverse genetics system for Borna disease virus
Borna disease virus (BDV) is an enveloped virus. Its non-segmented, negative-stranded RNA genome has the coding capability for six main polypeptides and has an organization characteristic of members of the order Mononegavirales. However, based on its unique genetics and biological features, BDV is considered to be the prototypic member of a new virus ...
Mar, Perez +4 more
openaire +2 more sources
Preliminary Studies on the Biology of Borna Disease Virus
Borna disease virus (BDV) is an unclassified agent that causes neurological disease in a wide range of animal species and possibly in humans. The infectious nature of BDV has been long established but, despite extensive progress on the pathogenesis of the infection, the aetiological agent is still uncharacterized.
C S, Duchala, K M, Carbone, O, Narayan
openaire +2 more sources
Borna disease virus 1 (BoDV-1) is neurotropic prototype of Bornaviruses causing neurological diseases and maintaining persistent infection in brain cells of mammalian species.
Lin Sun +9 more
doaj +1 more source

