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Borna disease virus, a newly classified nonsegmented negative-strand RNA virus with international distribution, infects a broad range of warm-blooded animals from birds to primates.
Carolyn G. Hatalski +2 more
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Borna Disease Virus and the Brain
Viruses with the ability to establish persistent infection in the central nervous system (CNS) can induce progressive neurologic disorders associated with diverse pathological manifestations. Clinical, epidemiological, and virological evidence supports the hypothesis that viruses contribute to human mental diseases whose etiology remains elusive ...
Gonzalez–Dunia, Daniel +2 more
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Borna disease virus and its role in the pathology of animals and humans
Infectious diseases that are caused by numerous pathogenic microorganisms – bacteria, viruses, protozoa or fungi – can be transmitted from patients or carriers to healthy people or animals.
A. O. Mikheev
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(1) Background: Vaccination of horses and sheep against Borna disease (BD) was common in endemic areas of Germany in the 20th century but was abandoned in the early 1990s.
Ralf Dürrwald +6 more
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Borna disease virus and psychiatry
Borna disease virus (BDV), a noncytolytic neurotropic nonsegmented negative-stranded RNA virus with a wide geographic distribution, infects several vertebrate animal species and causes an immune-mediated central nervous system (CNS) disease with various manifestations, depending on both host and viral factors.
O, Taieb +3 more
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Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease
Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus.
Kirsi S. Honkavuori +11 more
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Borna Disease Virus and Human Disease [PDF]
SUMMARYThe biology of Borna disease virus (BDV) strongly supports the likelihood of human infection with BDV or a variant of BDV. Thus far, the evidence supporting BDV infection in humans has initiated much controversy among basic and clinical scientists; only time and additional research will support or refute the hypothesis of human BDV infection ...
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Tardive dyskinetic syndrome in rats infected with Borna disease virus
Tardive Dyskinesia (TD) is a hyperkinetic movement disorder caused by chronic treatment of psychiatric patients with dopamine (DA) receptor blocking drugs (Stacy & Jankovic 1991).
Marylou V. Solbrig +3 more
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Maturation of Borna disease virus glycoprotein [PDF]
The maturation of Borna disease virus (BDV) glycoprotein GP was studied in regard to intracellular compartmentalization, compartmentalization signal‐domains, proteolytic processing, and packaging into virus particles. Our data show that BDV‐GP is (i) predominantly located in the endoplasmic reticulum (ER), (ii) partially exists in the ER already as ...
Eickmann, Markus +5 more
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Crystal Structure of the Borna Disease Virus Nucleoprotein [PDF]
Borna disease virus (BDV) causes an infection of the central nervous system in a wide range of vertebrates, which can fatally progress to an immune-mediated disease, called Borna disease. BDV is a member of the Mononegavirales, which also includes the highly infectious measles and Ebola viruses.
Rudolph, M. +5 more
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