Results 11 to 20 of about 2,958 (113)

Borna Disease Virus 1 as Cause of Fatal Meningoencephalomyelitis in Wild Hedgehogs, Germany, 2022–2025 [PDF]

Emerging Infectious Diseases
Borna disease virus 1 (BoDV-1) causes encephalitis with a fatality rate of >90% in domestic mammals and humans. Currently, the bicolored white-toothed shrew is the only known reservoir host. We report BoDV-1 infections in 15 wild European hedgehogs from
Effrosyni Michelakaki, Benjamin Schade, Brigitte Boehm, Eva Kappe, Marcel Suchowski, Anne Kupca, Magdalena Schumacher, Anna Maria Gager, Friederike Liesche-Starnecker, Sonja Fiedler, Eva Schwarz, Zoltan Bago, Andreas Blutke, Martin Beer, Dennis Rubbenstroth, Kaspar Matiasek   +15 more
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Human Borna disease virus 1 encephalitis shows marked pro-inflammatory biomarker and tissue immunoactivation during the course of disease [PDF]

Emerging Microbes and Infections, 2022
Human Borna disease virus 1 (BoDV-1) encephalitis is a severe emerging disease with a very high case-fatality rate. While the clinical disease, case definitions, diagnostic algorithms and neuropathology have been described, very little is known about the
Jessica Rauch, Johanna Friederike Steffen, Birgit Muntau, Jana Gisbrecht, Kirsten Pörtner, Christiane Herden, Hans Helmut Niller, Markus Bauswein, Dennis Rubbenstroth, Ute Mehlhoop, Petra Allartz, Dennis Tappe   +11 more
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Calu-3 cells as novel efficient cell culture system for Borna disease virus 1 (BoDV-1) [PDF]

Virus Research
Borna disease virus 1 (BoDV-1) is the causative agent of zoonotic infections resulting in severe encephalitis with a high case-fatality rate in humans. To search for an efficient in-vitro cell culture system for the generation of BoDV-1 virus stocks, we ...
Lisa Arnold, Vanessa Schwarz, Gertrud Knoll, André Gessner, Barbara Schmidt, Markus Bauswein   +5 more
doaj   +2 more sources

Ribavirin Treatment for Severe Schizophrenia with Anti-Borna Disease Virus 1 Antibodies 30 Years after Onset [PDF]

Case Reports in Psychiatry, 2023
Objective. Borna disease virus 1 (BoDV-1) was proven to cause fatal encephalitis in humans in 2018. However, the effects of persistent infections remain unclear.
Hidenori Matsunaga, Akio Fukumori, Kohji Mori, Takashi Morihara, Shunsuke Sato, Kyoko Kitauchi, Kanta Yanagida, Kazumi Taguchi, Tomoyuki Honda, Keizo Tomonaga   +9 more
doaj   +2 more sources

Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany [PDF]

Viruses, 2023
More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region in southern Germany, we conducted the seroepidemiological BoSOT study (“BoDV-1 after solid ...
Markus Bauswein, Lisa Eidenschink, Gertrud Knoll, Bernhard Neumann, Klemens Angstwurm, Saida Zoubaa, Markus J Riemenschneider, Benedikt M J Lampl, Matthias Pregler, Hans Helmut Niller, Jonathan Jantsch, André Gessner, Yvonne Eberhardt, Gunnar Huppertz, Torsten Schramm, Stefanie Kühn, Michael Koller, Thomas Drasch, Yvonne Ehrl, Bernhard Banas, Robert Offner, Barbara Schmidt, Miriam C. Banas   +22 more
doaj   +2 more sources

Lethal Borna disease virus 1 infections of humans and animals – in-depth molecular epidemiology and phylogeography [PDF]

Nature Communications
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, a fatal neurologic disorder of domestic mammals and humans, resulting from spill-over infection from its natural reservoir host, the bicolored white-toothed shrew (Crocidura leucodon)
Arnt Ebinger, Pauline D. Santos, Florian Pfaff, Ralf Dürrwald, Jolanta Kolodziejek, Kore Schlottau, Viktoria Ruf, Friederike Liesche-Starnecker, Armin Ensser, Klaus Korn, Reiner Ulrich, Jenny Fürstenau, Kaspar Matiasek, Florian Hansmann, Torsten Seuberlich, Daniel Nobach, Matthias Müller, Antonie Neubauer-Juric, Marcel Suchowski, Markus Bauswein, Hans-Helmut Niller, Barbara Schmidt, Dennis Tappe, Daniel Cadar, Timo Homeier-Bachmann, Viola C. Haring, Kirsten Pörtner, Christina Frank, Lars Mundhenk, Bernd Hoffmann, Jochen Herms, Wolfgang Baumgärtner, Norbert Nowotny, Jürgen Schlegel, Rainer G. Ulrich, Martin Beer, Dennis Rubbenstroth   +36 more
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Shedding of Infectious Borna Disease Virus-1 in Living Bicolored White-Toothed Shrews. [PDF]

PLoS ONE, 2015
Many RNA viruses arise from animal reservoirs, namely bats, rodents and insectivores but mechanisms of virus maintenance and transmission still need to be addressed.
Daniel Nobach, Manon Bourg, Sibylle Herzog, Hildburg Lange-Herbst, Jorge A Encarnação, Markus Eickmann, Christiane Herden   +6 more
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Spillover infections by rustrela virus, borna disease virus 1 and tick-borne encephalitis virus revealed by retrospective screening of mammalian encephalitis of unknown origin [PDF]

BMC Veterinary Research
Background Cross-species transmission of several viral neuropathogens may lead to fatal disease in incidental hosts. The newly discovered rustrela virus (RusV) as well as Borna disease virus 1 (BoDV-1), tick-borne encephalitis virus (TBEV), and highly ...
Anne Voss, Anne Günther, Olga Geit, Chloé Puget, Andreas Pauly, Karin Stiasny, Kore Schlottau, Martin Beer, Achim D. Gruber, Angele Breithaupt, Dennis Rubbenstroth, Lars Mundhenk   +11 more
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Long-Term Survival of Borna Disease Virus 1 (BoDV-1)-Encephalitis: An Exceptional Case with Valuable Insights for Pathophysiology and Disease Management [PDF]

Infectious Diseases and Therapy
Introduction Borna disease virus 1 (BoDV-1) encephalitis has a (sub)acute and mostly fatal course. Initial flu-like symptoms are typically followed by rapid progressive panencephalitis and death within weeks. No curative therapy exists so far. We present
Denis Grabova, Ida Wilkens, Matthias Klein, Suzette Heck, Viktoria Ruf, Sigrun Roeber, Michael Schmutzer-Sondergeld, Matthias Brendel, Robert Forbrig, Helena Klauss, Sabrina Katzdobler, Günter U. Höglinger, Konstantin Dimitriadis, Andreas Straube, Markus Bauswein, Martina Kinzig, Fritz Sörgel, Dennis Tappe, Ilias Masouris, Florian Schöberl   +19 more
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Increasing evidence of human infections by the neurotropic Borna disease virus 1 (BoDV-1) [PDF]

Virulence, 2023
Michaela Cain, Hinh Ly
doaj   +2 more sources