Results 41 to 50 of about 5,371 (185)

A Small Interfering RNA Cocktail Targeting the Nucleoprotein and Large Protein Genes Suppresses Borna Disease Virus Infection

Frontiers in Microbiology, 2019
Recently, Borna disease virus (BoDV-1)-related fatal encephalitis human cases have been reported, which highlights the potential of BoDV-1 to cause fatal human diseases.
Da Teng, Shunsuke Obika, Keiji Ueda, Tomoyuki Honda   +3 more
doaj   +1 more source

Use of avian bornavirus isolates to induce proventricular dilatation disease in conures [PDF]

, 2010
Avian bornavirus (ABV) is a newly discovered member of the family Bornaviridae that has been associated with the development of a lethal neurologic syndrome in birds, termed proventricular dilatation disease (PDD).
Briese, Thomas, Gray, Patricia, Honkavuori, Kirsi S., Hoppes, Sharman, Mirhosseini, Negin, Payne, Susan, Reddy, Sanjay M., Shivaprasad, H. L., Suchodolski, Paulette, Tizard, Ian, Villanueva, Itamar   +10 more
core   +3 more sources

Fatal Encephalitis Associated with Borna Disease Virus 1

New England Journal of Medicine, 2018
Fatal Borna Disease Virus 1 Infection This report describes a fatal case of severe encephalitis due to Borna disease virus 1.
Klaus Korn, Roland Coras, Tobias Bobinger, Sibylle M. Herzog, Hannes Lücking, Robert Stöhr, Hagen B. Huttner, Arndt Hartmann, Armin Ensser   +8 more
openaire   +1 more source

Prominent Efficacy of Amantadine against Human Borna Disease Virus Infection In Vitro and In Vivo. Comment on Fink et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses 2021, 13, 539

Viruses, 2022
Amantadine (1-amino-adamantane) is a versatile antiviral compound which has been licensed for decades against influenza viruses. During the Corona pandemic, its effect to inhibit SARS-CoV-2 in vitro has been investigated.
Liv Bode, Detlef E. Dietrich, Carsten W. Spannhuth, Hanns Ludwig   +3 more
doaj   +1 more source

Long-term Elevation of Complement Factors in Cerebrospinal Fluid of Patients With Borna Disease Virus 1 Encephalitis. [PDF]

J Infect Dis
Abstract Background Borna disease virus 1 (BoDV-1) causes rare but severe zoonotic infections in humans, presenting as encephalitis. The case-fatality risk is very high and no effective countermeasures have been established so far.
Bauswein M, Zoubaa S, Toelge M, Eidenschink L, Riemenschneider MJ, Neumann B, Lee DH, Eid E, Tappe D, Niller HH, Gessner A, Schmidt B, Bülow S, Angstwurm K.   +13 more
europepmc   +4 more sources

Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]

, 2010
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Dortmans, J.C.F.M., Koch, G., Peeters, B.P.H., Rottier, P.J.M.   +3 more
core   +2 more sources

Immune-mediated loss of transgene expression from virally transduced brain cells is irreversible, mediated by IFNγ, perforin, and TNFα, and due to the elimination of transduced cells [PDF]

, 2012
The adaptive immune response to viral vectors reduces vector-mediated transgene expression from the brain. It is unknown, however, whether this loss is caused by functional downregulation of transgene expression or death of transduced cells.
Ahmed, Ali, Asadi-Moghaddam, Bantug, Barcia, Barcia, Barcia, Barcia, Barcia, Barcia, Bergmann, Byrnes, Byrnes, Carlos Barcia, Chen, Chiocca, Chunyan Liu, Conrady, Dewey, Diamond, Glass, Griffin, Griffin, Hausmann, Huse, Jeffrey M Zirger, Jiang, Jiang, Jiang, Josee Bergeron, Kanegae, Kurt M Kroeger, Lang, Lowenstein, Lowenstein, Maria G Castro, Mariana Puntel, McGavern, Mia Wibowo, Määttä, Niyati Bondale, O'Keefe, Parra, Paxinos, Pedro R Lowenstein, Pulkkanen, Puntel, Rall, Rameen Moridzadeh, Shi, Smith-Arica, Southgate, Southgate, Thomas, Thomas, Wang, Wilkinson, Williamson, Wirth, Yang, Zambrowicz   +60 more
core   +1 more source

Rustrela Virus-Associated Encephalomyelitis (‘Staggering Disease’) in Cats from Eastern Austria, 1994–2016

Viruses, 2023
Clinical cases of ‘staggering disease’, a nonsuppurative encephalomyelitis associated with gait abnormalities in cats, have been documented for decades in Sweden. In Austria, an increased incidence was observed in the 1990s. Only recently, rustrela virus
Viktoria Weiss, Pia Weidinger, Julia Matt, Christiane Weissenbacher-Lang, Norbert Nowotny, Herbert Weissenböck   +5 more
doaj   +1 more source

Borna disease virus (BDV) infection in psychiatric patients and healthy controls in Iran [PDF]

, 2014
Background Borna disease virus (BDV) is an evolutionary old RNA virus, which infects brain and blood cells of humans, their primate ancestors, and other mammals.
Atashi, Hasti, Bode, Liv, Ludwig, Hanns, Maghsoudi, Nader, Mazaheri-Tehrani, Elham, Motamedi, Fereshteh, Shams, Jamal, Soori, Hamid   +7 more
core   +2 more sources

Intranasal Borna Disease Virus (BoDV-1) Infection: Insights into Initial Steps and Potential Contagiosity [PDF]

International Journal of Molecular Sciences, 2019
Mammalian Bornavirus (BoDV-1) typically causes a fatal neurologic disorder in horses and sheep, and was recently shown to cause fatal encephalitis in humans with and without transplant reception. It has been suggested that BoDV-1 enters the central nervous system (CNS) via the olfactory pathway.
Alexandra Kupke, Sabrina Becker, Konstantin Wewetzer, Barbara Ahlemeyer, Markus Eickmann, Christiane Herden   +5 more
openaire   +2 more sources