Results 11 to 20 of about 23,888 (256)

Protection-Free Strategy for the Synthesis of Boro-Depsipeptides in Aqueous Media under Microwave-Assisted Conditions

Molecules, 2022
In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu, Pei-Yao Liu, Bo-Cheng Wang, Pin-Rui Chen, Jing-Han Xiao, Ting-Yu Hsu, Kuan-Lin Pan, Zhi-Yin Lai, Yi-Wei Chen, Ying-Chuan Chen, Jen-Kun Chen, Po-Shen Pan   +11 more
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The Influence of Boron on the Structure and Properties of Hybrid Compounds Containing Zirconium and Phosphorus

Gels, 2022
In the present work, novel organic–inorganic hybrid materials containing boron, zirconium, and phosphorus were synthesized at different molar ratios, using the sol–gel method, starting from zirconyl chloride hexa-hydrate, triethyl borate, and phenyl ...
Petru Merghes, Gheorghe Ilia, Iosif Hulka, Vlad Chiriac, Narcis Varan, Vasile Simulescu   +5 more
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Boron Chemistry for Medical Applications

Molecules, 2020
Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly few are found in pharmaceutical drugs.
Fayaz Ali, Narayan S Hosmane, Yinghuai Zhu   +2 more
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Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective

Molecules, 2022
A standard goal of medicinal chemists has been to discover efficient and potent drug candidates with specific enzyme-inhibitor abilities. In this regard, boron-based bioactive compounds have provided amphiphilic properties to facilitate interaction with ...
Bhaskar C. Das, Nitesh K. Nandwana, Sasmita Das, Varsha Nandwana, Mohammed Adil Shareef, Yogarupa Das, Mariko Saito, Louis M. Weiss, Frankis Almaguel, Narayan S. Hosmane, Todd Evans   +10 more
doaj   +1 more source

Development of AMBER Parameters for Molecular Simulations of Selected Boron-Based Covalent Ligands

Molecules, 2023
Boron containing compounds (BCCs) aroused increasing interest in the scientific community due to their wide application as drugs in various fields. In order to design new compounds hopefully endowed with pharmacological activity and also investigate ...
Maria Assunta Chiacchio, Laura Legnani, Enrico Mario Alessandro Fassi, Gabriella Roda, Giovanni Grazioso   +4 more
doaj   +1 more source

Therapeutic Potential of Boron-Containing Compounds [PDF]

Future Medicinal Chemistry, 2009
Relative to carbon, hydrogen, nitrogen and oxygen, very little is currently known about boron in therapeutics. In addition, there are very few boron-containing natural products identified to date to serve as leads for medicinal chemists. Perceived risks of using boron and lack of synthetic methods to handle boron-containing compounds have caused the ...
Stephen J, Baker, Charles Z, Ding, Tsutomu, Akama, Yong-Kang, Zhang, Vincent, Hernandez, Yi, Xia   +5 more
openaire   +2 more sources

Interaction of the anion [2-B₁₀H₉O(CH₂)₄O]− with secondary amines

Тонкие химические технологии, 2022
Objectives. One of the most promising methods of treating malignant tumors is 10B-neutron capture therapy. While compounds based on cluster boron anions [BnHn]2− (n = 10, 12) are often used as boron-containing agents due to the very high specific ...
E. Yu. Matveev, S. S. Novikov, V. Ya. Levitskaya, A. I. Nichugovskiy, I. E. Sokolov, K. Yu. Zhizhin, N. T. Kuznetsov   +6 more
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Combining Two Types of Boron in One Molecule (To the 60th Anniversary of the First Synthesis of Carborane)

Chemistry, 2023
This review is an attempt to bring together the data from the literature on the synthesis and properties of icosahedral carborane derivatives, in which exo-polyhedral three- and four-coordinated boron substituents are attached directly to the carborane ...
Igor B. Sivaev
doaj   +1 more source

Boron Applications in Prevention, Diagnosis and Therapy for High Global Burden Diseases

Inorganics, 2023
The role of boron-containing compounds (BCCs) in medicine is growing [...]
Marvin A. Soriano-Ursúa
doaj   +1 more source

Organoboron Compounds: Effective Antibacterial and Antiparasitic Agents

Molecules, 2021
The unique electron deficiency and coordination property of boron led to a wide range of applications in chemistry, energy research, materials science and the life sciences.
Paolo Saul Coghi, Yinghuai Zhu, Hongming Xie, Narayan S. Hosmane, Yingjun Zhang   +4 more
doaj   +1 more source