Results 11 to 20 of about 615,627 (295)

Synthesis of biologically active boron-containing compounds. [PDF]

Medchemcomm, 2018
A review focused on the synthetic methods of bioactive boron-containing compounds.
Yang F, Zhu M, Zhang J, Zhou H.
europepmc   +5 more sources

Effects of boron-containing compounds on cardiovascular disease risk factors – A review

Journal of Trace Elements in Medicine and Biology, 2018
Boron is considered to be a biological trace element but there is substantial and growing support for it to be classified as an essential nutrient for animals and humans, depending on its speciation.
Ionut Donoiu, Johny Neamtu, Andrei Bita   +2 more
exaly   +4 more sources

THE INFLUENCE OF BORON-CONTAINING COMPOUNDS ON CARDIOVASCULAR HEALTH

Arta Medica, 2020
Objectives. Boron is a biological trace element which can be find in different natural compounds, but there is substantial and growing support for it to be classified as an essential nutrient for animals and humans.
Maria-Victoria Racu, Ion Romulus Scorei, Iurie Pînzaru   +2 more
doaj   +2 more sources

An automated positive selection screen in yeast provides support for boron-containing compounds as inhibitors of SARS-CoV-2 main protease [PDF]

Microbiology Spectrum
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus continues to cause severe disease and deaths in many parts of the world, despite massive vaccination efforts. Antiviral drugs to curb an ongoing infection remain a priority. The virus-
Sunniva Sigurdardóttir, Suélen Fernandes Silva, Ievgeniia Tiukova, Hanna Alalam, Ross D. King, Morten Grøtli, Leif A. Eriksson, Per Sunnerhagen   +7 more
doaj   +2 more sources

Theoretical Evaluation of Bortezomib and Other Boron-Containing Compounds as Inhibitors of SARS-CoV-2 Main Protease

, 2020
The aim of the present docking study was to explore the putative role of boronic moieties in molecules interacting on the binding site of the SARS-CoV-2 main protease.
Vega Valdez IR, Santiago-Quintana JM, ROSALEZ M, Farfan E, Soriano-Ursua MA.   +4 more
europepmc   +2 more sources

Development and Elucidation of a Novel Fluorescent Boron-Sensor for the Analysis of Boronic Acid-Containing Compounds

Sensors, 2017
Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods.
Yoshihide Hattori, Takuya Ogaki, Miki Ishimura, Yoichiro Ohta, Mitsunori Kirihata   +4 more
doaj   +2 more sources

Boron-Containing Compounds as Antimicrobial Agents to Tackle Drug-Resistant Bacteria

Pharmaceutical Fronts
Bacterial infections, especially those caused by drug-resistant bacterial pathogens, are crucial diseases that damage human health. In recent decades, several important boron-containing drugs have been marketed as anticancer agents or anti-infective ...
Zongkai Huang, Lang Bai, Jie Liu, Youfu Luo   +3 more
doaj   +2 more sources

Boron in Diet and Medicine: Mechanisms of Delivery and Detection [PDF]

Pharmaceuticals
Boron is a trace element with multifaceted chemical and biological properties that underpin its emerging relevance in human health and medicinal chemistry.
Dorota Bartusik-Aebisher, Izabela Rudy, Kacper Rogóż, David Aebisher, Gabriela Henrykowska   +4 more
doaj   +2 more sources

Discovery of boron-containing compounds as Aβ aggregation inhibitors and antioxidants for the treatment of Alzheimer's disease. [PDF]

Medchemcomm, 2018
Lu CJ, Hu J, Wang Z, Xie S, Pan T, Huang L, Li X.   +6 more
europepmc   +2 more sources

Protection-Free Strategy for the Synthesis of Boro-Depsipeptides in Aqueous Media under Microwave-Assisted Conditions

Molecules, 2022
In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu, Pei-Yao Liu, Bo-Cheng Wang, Pin-Rui Chen, Jing-Han Xiao, Ting-Yu Hsu, Kuan-Lin Pan, Zhi-Yin Lai, Yi-Wei Chen, Ying-Chuan Chen, Jen-Kun Chen, Po-Shen Pan   +11 more
doaj   +1 more source