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Boron Chemistry for Medical Applications [PDF]

Molecules, 2020
Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly few are found in pharmaceutical drugs.
Fayaz Ali, Narayan S Hosmane, Yinghuai Zhu   +2 more
doaj   +5 more sources

The Boron Advantage: The Evolution and Diversification of Boron’s Applications in Medicinal Chemistry

Pharmaceuticals, 2022
In this review, the history of boron’s early use in drugs, and the history of the use of boron functional groups in medicinal chemistry applications are discussed. This includes diazaborines, boronic acids, benzoxaboroles, boron clusters, and carboranes.
Katia Messner, Billy Vuong, Geoffrey K. Tranmer   +2 more
doaj   +4 more sources

Contemporary Research in Boron Chemistry. [PDF]

Chem Soc Rev, 2019
Guest editors Shih-Yuan Liu and Douglas W. Stephan introduce the Boron Chemistry themed issue of Chemical Society Reviews.
Liu SY, Stephan DW.
europepmc   +2 more sources

Boron-based fire retardancy for natural polymeric materials [PDF]

Frontiers in Chemistry
The shift from fossil resources to natural polymers as the building blocks of a global bioeconomy is hampered by the intrinsic flammability of these bio-derived materials.
Xuan Wang, Sheldon Q. Shi
doaj   +2 more sources

Boron’s Double Edge—Antibiotics, Toxins, and the Fine Line Between Them [PDF]

Molecules
Boron is a chemically distinctive bioelement whose electron-deficient structure enables reversible coordination with oxygen-rich functional groups such as diols and hydroxyls.
Valery M. Dembitsky, Alexander O. Terent'ev, Sergey V. Baranin, Ion Romulus Scorei   +3 more
doaj   +2 more sources

Metallomimetic Chemistry of Boron

Chemical Reviews, 2019
The study of main-group molecules that behave and react similarly to transition-metal (TM) complexes has attracted significant interest in recent decades.
Marc-André Legare, Conor Pranckevicius, Holger Braunschweig   +2 more
exaly   +2 more sources

Boron in Diet and Medicine: Mechanisms of Delivery and Detection [PDF]

Pharmaceuticals
Boron is a trace element with multifaceted chemical and biological properties that underpin its emerging relevance in human health and medicinal chemistry.
Dorota Bartusik-Aebisher, Izabela Rudy, Kacper Rogóż, David Aebisher, Gabriela Henrykowska   +4 more
doaj   +2 more sources

The Current State of the Art in PAMAM and PLL Dendrimers, Boron Clusters, and Their Complexes for Biomedical Use [PDF]

Biomedicines
Poly(amidoamine) (PAMAM) and poly-L-lysine (PLL) dendrimers have emerged as highly versatile macromolecular platforms with significant potential in biomedical applications, owing to their well-defined architecture, tunable surface chemistry, and capacity
Agnieszka Maria Kołodziejczyk, Edyta Błaszczyk, Bolesław T. Karwowski   +2 more
doaj   +2 more sources

Hexafluoroisopropylboranes and -Borates

Inorganics, 2023
Novel hexafluoroisopropylboranes (CF3)(CF2H)CFBH2·L and -borate anions [(CF3)(CF2H)CFBH2X]− with Lewis basic heterocyclic ligands L and the anionic substituents X = F− and CN− were obtained.
Ludwig Zapf, Maik Finze
doaj   +1 more source

Recent developments in the medicinal chemistry of single boron atom-containing compounds

Acta Pharmaceutica Sinica B, 2021
Various boron-containing drugs have been approved for clinical use over the past two decades, and more are currently in clinical trials. The increasing interest in boron-containing compounds is due to their unique binding properties to biological targets;
Shu Song, Ping Gao, Lin Sun, Dongwei Kang, J. Kongsted, Vasanthanathan Poongavanam, P. Zhan, Xinyong Liu   +7 more
semanticscholar   +1 more source