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A Novel <i>Closo</i>-<i>Ortho</i>-Carborane-Based Glucosamine Derivative as a Promising Agent for Boron Neutron Capture Therapy. [PDF]

open access: yesPharmaceuticals (Basel)
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Boron Neutron Capture Therapy for Cancer

Scientific American, 1990
Boron neutron capture therapy (BNCT) bring together two components that when kept separate have only minor effects on normal cells. The first component is a stable isotope of boron (boron 10) that can be concentrated in tumor cells. The second is a beam of low-energy neutrons that produces short-range radiation when absorbed, or captured, by the boron.
R F, Barth, A H, Soloway, R G, Fairchild
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Boron Neutron Capture Therapy

Physics of Atomic Nuclei, 2021
Fundamentals of boron neutron capture therapy of malignant tumors are outlined, and the current status of the development of epithermal-neutron sources on the basis of charged-particle accelerators is surveyed. Attention is additionally given to a neutron source based on a charged-particle accelerator belonging to a new type—a tandem accelerator with ...
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Utilizing neutron generators in boron neutron capture therapy

Applied Radiation and Isotopes, 2021
Neutron capture therapy (NCT) is a radiotherapeutic technique that is designed to utilize the neutron capture reaction and damage the tumor cells through the energy release from the reaction. Nuclear reactors are typically utilized in this therapy because of the high neutron fluence rate that can be achieved. There has been minimal work to evaluate the
Walid A, Metwally   +3 more
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Boron and Gadolinium Neutron Capture Therapy

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
C. Salt   +4 more
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Microdosimetry for Boron Neutron Capture Therapy

Radiation Research, 1992
Preclinical studies for boron neutron capture therapy (BNCT) using epithermal neutrons are ongoing at several laboratories. The absorbed dose in tumor cells is a function of the thermal neutron flux at depth, the microscopic boron concentration, and the size of the cell.
C S, Wuu   +4 more
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Boron neutron-capture therapy

Neutron News, 1990
Abstract Boron Neutron Capture Therapy (BNCT) is a method of radiation therapy based on the 10B(n,4He)7Li reaction that shows promise in the treatment of some malignant tumors of the brain and of the skin. Considerable research on neutron beam development and on the chemistry, pharmacology and toxicology of boron-containing drugs for BNCT is in ...
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