Results 1 to 10 of about 17,253 (188)

Lactam enables remote boronate rearrangements to C═N bonds [PDF]

Communications Chemistry
Remote boronate rearrangement of boronic acids to C═N bonds is a valuable in synthetic chemistry. Conventional approaches are constrained by the need to pre-install specialized directing groups onto the starting materials. Here, we report a lactam-driven
Jie Lei, Jia Xu, Xue Li, Wei Yan, Zhongzhu Chen, Zhigang Xu, Hong-yu Li   +6 more
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Reactive oxygen species-activated bioorthogonal chemistry in living systems enabled by boronate-caged dihydrotetrazines [PDF]

Nature Communications
Bioorthogonal chemistry has become a robust toolbox with growing applications in biology and medicine. To meet diverse needs in research, new types of on-demand bioorthogonal reactions capable of responding to biological triggers or exogenous stimuli are
Dongqing Ming, Jiaxue Zhang, Binsong Mu, Dongxue Peng, Yanjun Wang, Yangyang Kong, Wenjing Wang, Ling Chu, Rui Wang, Luping Liu   +9 more
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Catalytic asymmetric functionalization of bicyclo[1.1.0]butane boronic esters enabled by 1,2-oxygen migration [PDF]

Nature Communications
The formation of boronate complexes through the coordination of alkoxide salts with organoborons serves as key intermediates in transition-metal-catalyzed coupling reactions.
Xin-Yuan Zhu, Chong-Lei Ji, Tian-Ge Dong, De-Wei Gao   +3 more
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On the Mechanism of Random Handedness Generation in the Reactions of Heterocyclic Aldehydes with Diallylboronates [PDF]

Molecules
The mechanism of generation of products with opposite handedness in the reactions of heterocyclic aldehydes with diallylboronates was studied by NMR experiments and DFT computations.
Oleg Mikhailov, Ilya D. Gridnev
doaj   +2 more sources

Diastereoselective Synthesis of the Borylated d-Galactose Monosaccharide 3-Boronic-3-Deoxy-d-Galactose and Biological Evaluation in Glycosidase Inhibition and in Cancer for Boron Neutron Capture Therapy (BNCT)

Molecules, 2023
Drug leads with a high Fsp3 index are more likely to possess desirable properties for progression in the drug development pipeline. This paper describes the development of an efficient two-step protocol to completely diastereoselectively access a ...
Michela I. Simone
doaj   +1 more source

Boronated Cyanometallates

Inorganic Chemistry, 2022
Fourteen boronated cyanometallates ([M(CN-BR3)6]3/4/5– (M = Cr, Mn, Fe, Ru, Os, R = BPh3, B(2,4,6,-F3C6H2)3, B(C6F5)3) have been characterized by X-ray crystallography and spectroscopy [UV-vis-NIR, NMR, IR, spectroelectrochemistry, and magnetic circular dichroism (MCD)]; CASSCF+NEVPT2 methods were employed in calculations of electronic structures. For (
Brendon J. McNicholas, Cherish Nie, Anex Jose, Paul H. Oyala, Michael K. Takase, Larry M. Henling, Alexandra T. Barth, Alessio Amaolo, Ryan G. Hadt, Edward I. Solomon, Jay R. Winkler, Harry B. Gray, Emmanuelle Despagnet-Ayoub   +12 more
openaire   +3 more sources

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Molecules, 2022
In this study, privileged boronic acid ester was introduced into the right wing of etravirine (ETR) to obtain a series of novel boronate-containing derivatives.
Da Feng, Hao Lin, Liyang Jiang, Zhao Wang, Yanying Sun, Zhongxia Zhou, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu   +10 more
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A simple generic method for analyzing water sensitive pinacol boronate compounds by hydrophilic interaction liquid chromatography

Journal of Chromatography Open, 2022
Pinacol boronates are widely used in the pharmaceutical and biomedical industries as primary building blocks for many chemical reactions, such as Suzuki coupling.
Lulu Dai, Joseph Gonzalez, Kelly Zhang
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Liquid Crystalline Benzoic Acid Ester MIDA Boronates: Synthesis and Mesomorphic Properties

Organic Materials, 2020
Two series of N-methyliminodiacetic acid (MIDA) boronates were prepared and their mesomorphic properties were investigated. MIDA-substituted benzoic acid esters were synthesized via the Mitsunobu reaction.
Christopher Schilling, Finn Schulz, Andreas Köhn, Sabine Laschat   +3 more
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Thiol Peroxidases as Major Regulators of Intracellular Levels of Peroxynitrite in Live Saccharomyces cerevisiae Cells

Antioxidants, 2020
Thiol peroxidases (TP) are ubiquitous and abundant antioxidant proteins of the peroxiredoxin and glutathione peroxidase families that can catalytically and rapidly reduce biologically relevant peroxides, such as hydrogen peroxide and peroxynitrite ...
André Luís Condeles, Fernando Gomes, Marcos Antonio de Oliveira, Luís Eduardo Soares Netto, José Carlos Toledo Junior   +4 more
doaj   +1 more source