Results 41 to 50 of about 8,945,775 (339)

Boronic Acids as Prospective Inhibitors of Metallo-β-Lactamases: Efficient Chemical Reaction in the Enzymatic Active Site Revealed by Molecular Modeling

Molecules, 2021
Boronic acids are prospective compounds in inhibition of metallo-β-lactamases as they form covalent adducts with the catalytic hydroxide anion in the enzymatic active site upon binding.
Alexandra V. Krivitskaya, Maria G. Khrenova   +1 more
doaj   +1 more source

Facile Fabrication of Hierarchically Porous Boronic Acid Group-Functionalized Monoliths With Optical Activity for Recognizing Glucose With Different Conformation

Frontiers in Chemistry, 2022
At present, various materials based on helical polymers are nanoparticle or microsphere, which is not ease of use in practical application. Accordingly, facile preparation hierarchically porous monolith based on helical polymer needs to be developed ...
Yan Wang, Luwei Zhang, Yu-I Hsu, Taka-Aki Asoh, Hiroshi Uyama   +4 more
doaj   +1 more source

Hydrogel Glucose Sensor with In Vivo Stable Fluorescence Intensity Relying on Antioxidant Enzymes for Continuous Glucose Monitoring

iScience, 2020
Summary: Hydrogel glucose sensors with boronic acid-based fluorescence intensity theoretically hold promise to improve in vivo continuous glucose monitoring (CGM) by facilitating long-lasting accuracy.
Jun Sawayama, Teru Okitsu, Akihiro Nakamata, Yoshihiro Kawahara, Shoji Takeuchi   +4 more
doaj   +1 more source

Electrophilic Trifluoromethylselenolation of Boronic Acids [PDF]

Molecules, 2017
Trifluoromethylselenylated compounds are emergent compounds with interesting physicochemical properties that still suffer from a lack of efficient synthetic methods. We recently developed an efficient one-pot strategy to generate in situ CF3SeCl and use it in various reactions.
Ghiazza, Clément, Tlili, Anis, Billard, Thierry   +2 more
openaire   +4 more sources

Covalent adaptable networks using boronate linkages by incorporating TetraAzaADamantanes

Frontiers in Chemistry, 2023
Boronic esters prepared by condensation of boronic acids and diols have been widely used as dynamic covalent bonds in the synthesis of both discrete assemblies and polymer networks.
Simon van Hurne, Marijn Kisters, Maarten M. J. Smulders   +2 more
doaj   +1 more source

Boronic acid with high oxidative stability and utility in biological contexts

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Like thiols, boronic acids are unstable to oxidation in biological contexts, limiting their utility. We discovered that the rate-limiting step in the oxidation of a boronic acid can be slowed by the installation of a pendant carboxyl group ...
B. Graham, I. Windsor, Brian Gold, Ronald T. Raines   +3 more
semanticscholar   +1 more source

Boronic Acid-Based Electrochemical Sensors for Detection of Biomolecules

International Journal of Electrochemical Science, 2013
Boronic acids can form reversible covalent bonds with 1, 2- or 1, 3-diols to generate five or six-membered cyclic complexes. Thus, boronic acid functionalized compounds and materials have attracted much attention in both chemistry and biology as the ...
Lin Liu, Ning Xia, Yun Xing, Dehua Deng
doaj   +1 more source

Boronic-Acid-Accelerated Electrophilic Activation of Unprotected Maltols to NSubstituted Hydroxypyridinones in Water

, 2022
3,4-Hydroxypyridinone (3,4-HOPO) is a vital metal-chelating pharmacophore. However, the efficient synthesis has been a long-standing problem in drug development.
Wenteng Chen, Xiuwen Zhong, Yongping Yu, Lei Zhang (38117), Wenteng Chen (1528783), Jiaan Shao (1528792), Xiuwen Zhong (11427934), Lei Zhang, Di Ke, Jiaan Shao, Di Ke (11432314), Yongping Yu (1520146)   +11 more
core   +1 more source

A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection [PDF]

, 2018
A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection.
Ashley, Jones, Souad, Elfecky, Wenbo, Chen, Toby, Jenkins, Adam, Sedgwick, Steven, Bull, Suying, Xu, Tony, James, John, Fossey, George, Williams   +9 more
core   +2 more sources

A boronic acid-functionalized phthalocyanine with an aggregation-enhanced photodynamic effect for combating antibiotic-resistant bacteria

Chemical Science, 2020
A boronic acid functionalized phthalocyanine displays aggregation-enhanced reactive oxygen species (ROS) generation and excellent photodynamic antibacterial activity.
Eunhye Lee, Xing-Shu Li, Juwon Oh, Nahyun Kwon, Gyoungmi Kim, Dongho Kim, Juyoung Yoon   +6 more
semanticscholar   +1 more source