Results 31 to 40 of about 2,531,458 (293)

Boronic Acids as Prospective Inhibitors of Metallo-β-Lactamases: Efficient Chemical Reaction in the Enzymatic Active Site Revealed by Molecular Modeling

open access: yesMolecules, 2021
Boronic acids are prospective compounds in inhibition of metallo-β-lactamases as they form covalent adducts with the catalytic hydroxide anion in the enzymatic active site upon binding.
Alexandra V. Krivitskaya   +1 more
doaj   +1 more source

Hydrogel Glucose Sensor with In Vivo Stable Fluorescence Intensity Relying on Antioxidant Enzymes for Continuous Glucose Monitoring

open access: yesiScience, 2020
Summary: Hydrogel glucose sensors with boronic acid-based fluorescence intensity theoretically hold promise to improve in vivo continuous glucose monitoring (CGM) by facilitating long-lasting accuracy.
Jun Sawayama   +4 more
doaj   +1 more source

Electrophilic Trifluoromethylselenolation of Boronic Acids [PDF]

open access: yesMolecules, 2017
Trifluoromethylselenylated compounds are emergent compounds with interesting physicochemical properties that still suffer from a lack of efficient synthetic methods. We recently developed an efficient one-pot strategy to generate in situ CF3SeCl and use it in various reactions.
Ghiazza, Clément   +2 more
openaire   +4 more sources

Distinct color changes in hydrogen peroxide-responsive thin films consisting of boronic acid-containing polymers

open access: yes, 2023
A novel methodology for the preparation of hydrogen peroxide (H2O2)-responsive thin-film sensors that display distinct color changes was developed. Boronic acid-containing films were obtained through the copolymerization of boronic acid and tertiary ...
Yasumasa, Kanekiyo   +3 more
core   +1 more source

Covalent adaptable networks using boronate linkages by incorporating TetraAzaADamantanes

open access: yesFrontiers in Chemistry, 2023
Boronic esters prepared by condensation of boronic acids and diols have been widely used as dynamic covalent bonds in the synthesis of both discrete assemblies and polymer networks.
Simon van Hurne   +2 more
doaj   +1 more source

Boronic-Acid-Accelerated Electrophilic Activation of Unprotected Maltols to NSubstituted Hydroxypyridinones in Water

open access: yes, 2022
3,4-Hydroxypyridinone (3,4-HOPO) is a vital metal-chelating pharmacophore. However, the efficient synthesis has been a long-standing problem in drug development.
Wenteng Chen   +11 more
core   +1 more source

Tuning Imine and Boronic Acid Reactivity with Neighboring Group Effects: Iminoboronates and Diazaborines in Bioconjugation Chemistry, Sensor Development, and Stimuli-Responsive Materials [PDF]

open access: yes, 2023
Dynamic covalent chemistry (DCC) are reversible reactions at chemical equilibrium. Owing to their reversible dynamics, these reactions represent an expansive toolbox for the development bioconjugation techniques and stimuli responsive materials.
Dylan Wythe, Domaille, Jack, Haggett
core   +1 more source

Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery

open access: yesSensors, 2016
Boronic acid-containing (co)polymers have fascinated researchers for decades, garnering attention for their unique responsiveness toward 1,2- and 1,3-diols, including saccharides and nucleotides. The applications of materials that exert this property are
Gertjan Vancoillie, Richard Hoogenboom
doaj   +1 more source

Highly Diastereo- and Enantioselective Allylboration of Aldehydes using alpha-Substituted Allyl/Crotyl Pinacol Boronic Esters via in Situ Generated Borinic Esters [PDF]

open access: yes, 2013
Readily available, alpha-substituted allyl/crotyl pinacol boronic esters often give low E/Z selectivity (with Z favored) in reactions with aldehydes. We found that addition of nBuLi to the pinacol boronic ester followed by trapping of the alkoxide with ...
Jack L.‐Y. Chen   +10 more
core   +1 more source

Using Visible Light to Tune Boronic Acid–ester Equilibria [PDF]

open access: yes, 2020
We report a series of azobenzene boronic acids that reversibly control the extent of diol binding via photochemical isomerization. When the boronic acid is ortho to the azo group, the thermodynamically-favored E isomer binds weakly with diols to form ...
Joseph, Accardo   +3 more
core   +2 more sources

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