Results 51 to 60 of about 2,531,458 (293)

The combined-disk boronic acid test as an accurate strategy for the detection of KPC carbapenemase in Central America

open access: yesJournal of Infection in Developing Countries, 2016
Introduction: Carbapenemase-producing Klebsiella pneumoniae (KPC) outbreaks may cause a huge economical burden on developing countries. Furthermore, KPC can be challenging to detect.
Julio Zúñiga   +4 more
doaj   +1 more source

Mild, Organo-Catalysed Borono-Deamination as a Key to Late-Stage Pharmaceutical Precursors and 18F-Labelled Radiotracers

open access: yesFrontiers in Chemistry, 2022
A tris(pentafluorophenyl)borane catalysed method for the synthesis of boronic acid esters from aromatic amines in yields of up to 93% was devised.
Raúl M. Pérez-García   +4 more
doaj   +1 more source

Boronic acid-modified cell-penetrating peptide exhibits superior performance over natural TAT peptide

open access: yesFrontiers in Chemical Biology
This study explores an enhancement to a cell-penetrating peptide (CPP), specifically cyclic deca arginine (cR10), by modifying it with boronic acid to improve the delivery efficiency of ubiquitin (Ub), an essential protein that plays various roles in ...
Pritam Ghosh
doaj   +1 more source

Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study

open access: yesMolecules, 2015
Cross-coupling reactions between 2-methyl-2-propen-1-ol and various boronic acids are used to obtain aromatic-(2-methylallyl) derivatives. However, deboronation or isomerization side reactions may occur for several boronic acids.
Clémence Tabélé   +4 more
doaj   +1 more source

A Red-Emitting Fluorescence Sensor for Detecting Boronic Acid-Containing Agents in Cells

open access: yesSensors, 2022
The amount and localization of boron-10 atoms delivered into tumor cells determines the therapeutic effect of boron neutron capture therapy (BNCT) and, consequently, efforts have been directed to develop fluorescence sensors to detect intracellular ...
Naoya Kondo   +3 more
doaj   +1 more source

Carbohydrate-Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin-Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM. [PDF]

open access: yesAdv Sci (Weinh)
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Ge H   +13 more
europepmc   +2 more sources

Click Reactions and Boronic Acids: Applications, Issues, and Potential Solutions

open access: yesMolecules, 2010
Boronic acids have been widely used in a wide range of organic reactions, in the preparation of sensors for carbohydrates, and as potential pharmaceutical agents.
Chaofeng Dai   +3 more
doaj   +1 more source

A Theoretical Model to Study the Interaction Between Boronic Acids and Insulin [PDF]

open access: yes, 2020
Boronic acids are widely used in various applications in view of their ability to recognize and bind at specific sites of the biological molecules to mimic several processes.
Kamlesh, Kumari   +2 more
core   +1 more source

Application of an R-group search technique in the molecular design of dipeptidyl boronic acid proteasome inhibitors [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
In this work, a 3D-QSAR model involving for 40 dipeptidyl boronic acid proteasome inhibitors was built based on Topomer CoMFA. The multiple correlation coefficient of fitting, cross-validation and external validation were 0.908, 0.647 and 0.703 ...
Tong Jian-Bo   +3 more
doaj   +1 more source

Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection

open access: yesFrontiers in Medicine, 2022
Various chemical probes for the detection of reactive oxygen species have been developed to examine oxidative stress associated with different pathologies.
Misaki Matsumoto   +10 more
doaj   +1 more source

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