Results 51 to 60 of about 2,531,458 (293)
Introduction: Carbapenemase-producing Klebsiella pneumoniae (KPC) outbreaks may cause a huge economical burden on developing countries. Furthermore, KPC can be challenging to detect.
Julio Zúñiga +4 more
doaj +1 more source
A tris(pentafluorophenyl)borane catalysed method for the synthesis of boronic acid esters from aromatic amines in yields of up to 93% was devised.
Raúl M. Pérez-García +4 more
doaj +1 more source
This study explores an enhancement to a cell-penetrating peptide (CPP), specifically cyclic deca arginine (cR10), by modifying it with boronic acid to improve the delivery efficiency of ubiquitin (Ub), an essential protein that plays various roles in ...
Pritam Ghosh
doaj +1 more source
Cross-Coupling Synthesis of Methylallyl Alkenes: Scope Extension and Mechanistic Study
Cross-coupling reactions between 2-methyl-2-propen-1-ol and various boronic acids are used to obtain aromatic-(2-methylallyl) derivatives. However, deboronation or isomerization side reactions may occur for several boronic acids.
Clémence Tabélé +4 more
doaj +1 more source
A Red-Emitting Fluorescence Sensor for Detecting Boronic Acid-Containing Agents in Cells
The amount and localization of boron-10 atoms delivered into tumor cells determines the therapeutic effect of boron neutron capture therapy (BNCT) and, consequently, efforts have been directed to develop fluorescence sensors to detect intracellular ...
Naoya Kondo +3 more
doaj +1 more source
Carbohydrate-Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin-Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM. [PDF]
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Ge H +13 more
europepmc +2 more sources
Click Reactions and Boronic Acids: Applications, Issues, and Potential Solutions
Boronic acids have been widely used in a wide range of organic reactions, in the preparation of sensors for carbohydrates, and as potential pharmaceutical agents.
Chaofeng Dai +3 more
doaj +1 more source
A Theoretical Model to Study the Interaction Between Boronic Acids and Insulin [PDF]
Boronic acids are widely used in various applications in view of their ability to recognize and bind at specific sites of the biological molecules to mimic several processes.
Kamlesh, Kumari +2 more
core +1 more source
Application of an R-group search technique in the molecular design of dipeptidyl boronic acid proteasome inhibitors [PDF]
In this work, a 3D-QSAR model involving for 40 dipeptidyl boronic acid proteasome inhibitors was built based on Topomer CoMFA. The multiple correlation coefficient of fitting, cross-validation and external validation were 0.908, 0.647 and 0.703 ...
Tong Jian-Bo +3 more
doaj +1 more source
Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection
Various chemical probes for the detection of reactive oxygen species have been developed to examine oxidative stress associated with different pathologies.
Misaki Matsumoto +10 more
doaj +1 more source

