Results 11 to 20 of about 18,230 (257)

Bioactivity of boronic acid derivative homodimers

Results in Chemistry, 2022
Homodimers that deployed boronic acids and their esters in their termini, namely boronic acid derivative homodimers, were designed. The boronic acid pinacol ester homodimer displayed antiviral activity and the boronic acid homodimer, in contrast, exerted
Kaori Ota, Jian-Rong Zhou, Kazumi Yokomizo, Tomohiro Kozako, Shin-ichiro Honda, Nobuhiro Kashige, Makoto Furutachi, Kunihiro Sumoto   +7 more
doaj   +1 more source

Applications of the Reversible Boronic Acids/Boronate Switch to Nucleic Acids

The Chemical Record, 2022
AbstractOver the last decades, boron and nucleic acids chemistries have gained a lot of attention for biological, medicinal and analytical applications. Our laboratory has a long‐standing interest in both chemistries and owing to the ability of boronic acids to react with cis‐diol function in aqueous media we developed over the years a variety of ...
Mégane Debiais, Jean‐Jacques Vasseur, Michael Smietana   +2 more
openaire   +2 more sources

Reverse Screening of Boronic Acid Derivatives: Analysis of Potential Antiproliferative Effects on a Triple-Negative Breast Cancer Model In Vitro

Inorganics, 2023
It has been demonstrated that different organoboron compounds interact with some well-known molecular targets, including serine proteases, transcription factors, receptors, and other important molecules.
Miguel Ortiz-Flores, Marcos González-Pérez, Andrés Portilla, Marvin A. Soriano-Ursúa, Javier Pérez-Durán, Araceli Montoya-Estrada, Guillermo Ceballos, Nayelli Nájera   +7 more
doaj   +1 more source

Supramolecular Caffeic Acid and Bortezomib Nanomedicine: Prodrug Inducing Reactive Oxygen Species and Inhibiting Cancer Cell Survival

Pharmaceutics, 2020
Phenolics from plant materials have garnered attention in nanomedicine research, due to their various medicinal properties. Caffeic acid, a phenolic compound that is abundant in coffee beans, has been proven to have anticancer effects, due to its ...
Ludwig Erik Aguilar, Se Rim Jang, Chan Hee Park, Kang Min Lee   +3 more
doaj   +1 more source

Electrophilic Trifluoromethylselenolation of Boronic Acids [PDF]

Molecules, 2017
Trifluoromethylselenylated compounds are emergent compounds with interesting physicochemical properties that still suffer from a lack of efficient synthetic methods. We recently developed an efficient one-pot strategy to generate in situ CF3SeCl and use it in various reactions.
Ghiazza, Clément, Tlili, Anis, Billard, Thierry   +2 more
openaire   +4 more sources

Advancing Glycan Analysis: A New Platform Integrating SERS, Boronic Acids, and Machine Learning Algorithms

Advanced Sensor Research, 2023
Glycans are the most abundant fundamental biomolecules, but profiling glycans is challenging due to their structural complexity. To address this, a novel glycan detection platform is developed by integrating surface‐enhanced Raman spectroscopy (SERS ...
Qiang Hu, Dacheng Kuai, Hyundo Park, Haley Clark, Perla B. Balbuena, Joseph Sang‐Il Kwon, Hung‐Jen Wu   +6 more
doaj   +1 more source

Facile Fabrication of Hierarchically Porous Boronic Acid Group-Functionalized Monoliths With Optical Activity for Recognizing Glucose With Different Conformation

Frontiers in Chemistry, 2022
At present, various materials based on helical polymers are nanoparticle or microsphere, which is not ease of use in practical application. Accordingly, facile preparation hierarchically porous monolith based on helical polymer needs to be developed ...
Yan Wang, Luwei Zhang, Yu-I Hsu, Taka-Aki Asoh, Hiroshi Uyama   +4 more
doaj   +1 more source

Hydrogel Glucose Sensor with In Vivo Stable Fluorescence Intensity Relying on Antioxidant Enzymes for Continuous Glucose Monitoring

iScience, 2020
Summary: Hydrogel glucose sensors with boronic acid-based fluorescence intensity theoretically hold promise to improve in vivo continuous glucose monitoring (CGM) by facilitating long-lasting accuracy.
Jun Sawayama, Teru Okitsu, Akihiro Nakamata, Yoshihiro Kawahara, Shoji Takeuchi   +4 more
doaj   +1 more source

Boronic Acids as Prospective Inhibitors of Metallo-β-Lactamases: Efficient Chemical Reaction in the Enzymatic Active Site Revealed by Molecular Modeling

Molecules, 2021
Boronic acids are prospective compounds in inhibition of metallo-β-lactamases as they form covalent adducts with the catalytic hydroxide anion in the enzymatic active site upon binding.
Alexandra V. Krivitskaya, Maria G. Khrenova   +1 more
doaj   +1 more source

Covalent adaptable networks using boronate linkages by incorporating TetraAzaADamantanes

Frontiers in Chemistry, 2023
Boronic esters prepared by condensation of boronic acids and diols have been widely used as dynamic covalent bonds in the synthesis of both discrete assemblies and polymer networks.
Simon van Hurne, Marijn Kisters, Maarten M. J. Smulders   +2 more
doaj   +1 more source