Results 31 to 40 of about 12,942 (258)
Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center
Biochemistry, 2020 Boronic acids have been successfully employed as inhibitors of hydrolytic enzymes. Typically, an enzymatic nucleophile catalyzing hydrolysis adds to the electrophilic boron atom forming a tetrahedral species that mimics the intermediate(s)/transition state(s) for the hydrolysis reaction.
Amar Nath Sharma +4 more
openaire +3 more sources
Advanced Engineering Materials, EarlyView.This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele +2 more
wiley +1 more source
Pharmaceutics, 2016 Boronic acids have been widely investigated for their potential use as glucose sensors in glucose responsive polymeric insulin delivery systems. Interactions between cyclic diols and boronic acids, anchored to polymeric delivery systems, may result in ...
Nabil A. Siddiqui +3 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical research due to their exceptional oxophilicity, low toxicity, and unique structure. They are known as potent enzyme inhibitors, cancer therapy capture agents, and can
Mothana K. Al-Omari +12 more
doaj +1 more source
Defunctionalisation catalysed by boron Lewis acids
Chemical Science, 2020 The combination of boron Lewis acid catalysts and hydride sources enables the cleavage of various carbon–heteroatom bonds.
Huaquan Fang, Martin Oestreich
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Advanced Functional Materials, EarlyView.Liquid‐phase transmission electron microscopy enables direct observation of nucleation and growth processes in solution. This review is dedicated to the remembrance of Helmut Cölfen and highlights recent studies on complex materials—oxides, biominerals, organic–inorganic crystals—which were central to his research activity. It summarizes key milestones,
Charles Sidhoum +5 more
wiley +1 more source
ChemElectroChemAryl organoboron reagents play an important role in modern organic synthesis, and interest in radical‐based coupling reactions from these precursors has grown rapidly.
Enqi Feng +5 more
doaj +1 more source
Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
Nature Communications, 2021 Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction
Kai Yang +5 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong +5 more
wiley +1 more source
Electrochemical Biosensors Based on Ferroceneboronic Acid and Its Derivatives: A Review
Biosensors, 2014 We review recent progress in the development of electrochemical biosensors based on ferroceneboronic acid (FcBA) and ferrocene (Fc)-modified boronic acids.
Baozhen Wang +3 more
doaj +1 more source