Results 141 to 150 of about 86,629 (276)

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

open access: yesJournal of Internal Medicine, Volume 299, Issue 2, Page 196-215, February 2026.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego   +7 more
wiley   +1 more source

Bortezomib

open access: yesIndian Journal of Medical and Paediatric Oncology, 2010
openaire   +4 more sources

Design and Synthesis of Boron‐Containing Noncanonical Amino Acids With Enhanced Stability and Solubility

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 3, January 22, 2026.
We report a new class of boron‐containing noncanonical amino acids with improved aqueous solubility and stability. Structural tuning around the boron center enhances biological compatibility, and unique fluorescence properties suggest applications in protein engineering and biosensing, advancing boron‐based tools for chemical biology and drug discovery.
Eunsol Jo   +10 more
wiley   +1 more source

Dihydrolipoamide dehydrogenase (DLD) is a novel molecular target of bortezomib

open access: yesCell Death and Disease
Proteasome inhibitors (PIs), such as bortezomib and calfizomib, were backbone agents in the treatment of multiple myeloma (MM). In this study, we investigated bortezomib interactors in MM cells and identified dihydrolipoamide dehydrogenase (DLD) as a ...
Yu Feng   +14 more
doaj   +1 more source

Direct and Natural Killer Cell-Mediated Antitumor Effects of Low-Dose Bortezomib in Hepatocellular Carcinoma [PDF]

open access: hybrid, 2008
Sorin Armeanu   +8 more
openalex   +1 more source

Epigenetic reprogramming in multiple myeloma—Challenges and opportunities

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar   +2 more
wiley   +1 more source

Chemoresistance of PRAME-expressing melanoma cell can be resolved with help of bortezomib

open access: diamond, 2019
V. A. Misyurin   +11 more
openalex   +2 more sources

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