Results 21 to 30 of about 12,716 (277)

Iridium-Catalyzed Silylation of Five-Membered Heteroarenes: High Sterically Derived Selectivity from a Pyridyl-Imidazoline Ligand. [PDF]

, 2020
The steric effects of substituents on five-membered rings are less pronounced than those on six-membered rings because of the difference in bond angles. Thus, the regioselectivities of reactions of five-membered heteroarenes that occur with selectivities
Hartwig, John F, Karmel, Caleb, Kharitonova, Elena V, Rubel, Camille Z   +3 more
core   +1 more source

Borylated Methylenephosphonium Salts: Precursors of Elusive Boryl(phosphino)carbenes [PDF]

Journal of the American Chemical Society, 2010
The synthesis of a new family of boryl-substituted methylenephosphonium derivatives, the phosphorus analogues of iminium salts, has been developed. They were used in the preparation of the first stable boryl(phosphino)carbene, which has been fully characterized by NMR spectroscopy and X-ray crystallography.
Lavigne, Florie, Maerten, Eddy, Alcaraz, Gilles, Saffon-Merceron, Nathalie, Acosta-Silva, Carles, Branchadell, Vicenç, Baceiredo, Antoine   +6 more
openaire   +2 more sources

Electrochemical Borylation of Carboxylic Acids [PDF]

Proceedings of the National Academy of Sciences, 2021
A simple electrochemically mediated method for the conversion of alkyl carboxylic acids to their borylated congeners is presented. This protocol features an undivided cell setup with inexpensive carbon-based electrodes and exhibits a broad substrate scope and scalability in both flow and batch reactors. The use of this method in challenging contexts is
Lisa M. Barton, Longrui Chen, Donna G. Blackmond, Phil S. Baran   +3 more
openaire   +3 more sources

Borylation directed borylation of N-alkyl anilines using iodine activated pyrazaboles [PDF]

Chemical Science, 2023
Doubly electrophilic pyrazabole derivatives (pyrazabole = [H2B(μ-C3N2H3)]2) combined with one equiv. of base effect the ortho-borylation of N-alkyl anilines.
C. R. P. Millet, E. Noone, A. V. Schellbach, J. Pahl, J. Łosiewicz, G. S. Nichol, M. J. Ingleson   +6 more
openaire   +2 more sources

Palladium-Catalyzed Cross-Coupling Reactions of Borylated Alkenes for the Stereoselective Synthesis of Tetrasubstituted Double Bond

Organics, 2022
The stereoselective formation of tetrasubstituted alkenes remains one of the key goals of modern organic synthesis. In addition to other methods, the stereoselective synthesis of tetrasubstituted alkenes can be achieved by means of cross-coupling ...
Tomáš Tobrman, Sergej Mrkobrada
doaj   +1 more source

Tri(boryl)alkanes and Tri(boryl)alkenes: The Versatile Reagents [PDF]

Molecules, 2020
The interest of organoboron chemistry in organic synthesis is growing, together with the development of new and versatile polyborated reagents. Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being ...
Oriol Salvadó, Elena Fernández
openaire   +3 more sources

Asymmetric Synthesis of 1-Heteroaryl-1-arylalkyl Tertiary Alcohols and 1-Pyridyl-1-arylethanes by Lithiation-Borylation Methodology [PDF]

, 2013
The synthesis of highly enantioenriched alpha-heterocyclic tertiary alcohols has been achieved via lithiation-borylation of a configurationally stable lithiated carbamate and heterocyclic pinacol boronic esters followed by oxidation. Protodeboronation of
Aggarwal V. K., Biradar D. B., Biradar D. B., Carstens A., Charlotte G. Watson, Chen C.-A., Cozzi P. G., Dosa P. I., García C., García C., García C., Garg D. C., Greene M. A., Hatano M., Hatano M., Hatano M., Hoppe D., Hu Q., Kanai M., Luderer M. R., Madduri A. V. R., Madduri A. V. R., Maity P., Matsunaga N., Messaoudi S., Moree W. J., Nave S., Ou L., Pathak T. P., Ramón D. J., Ramón D. J., Shi S.-L, Shibasaki M., Song S., Starck J. P., Stymiest J. L., Taylor B. L. H., Varinder K. Aggarwal, Wada R., Weber B., Yus M., Yus M.   +41 more
core   +3 more sources

One-Pot Iridium Catalyzed C–H Borylation/Sonogashira Cross-Coupling: Access to Borylated Aryl Alkynes

Molecules, 2020
Borylated aryl alkynes have been synthesized via one-pot iridium catalyzed C–H borylation (CHB)/Sonogashira cross-coupling of aryl bromides. Direct borylation of aryl alkynes encountered problems related to the reactivity of the alkyne under CHB ...
Ghayoor A. Chotana, Jose R. Montero Bastidas, Susanne L. Miller, Milton R. Smith, Robert E. Maleczka   +4 more
doaj   +1 more source

Palladium-catalyzed solid-state borylation of aryl halides using mechanochemistry

Beilstein Journal of Organic Chemistry, 2022
This study describes the solid-state palladium-catalyzed cross-coupling between aryl halides and bis(pinacolato)diboron using ball milling. The reactions were completed within 10 min for most aryl halides to afford a variety of synthetically useful ...
Koji Kubota, Emiru Baba, Tamae Seo, Tatsuo Ishiyama, Hajime Ito   +4 more
doaj   +1 more source

Cu-Catalyzed Decarboxylative Borylation [PDF]

ACS Catalysis, 2018
A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope,
Jie Wang, Ming Shang, Helena Lundberg, Karla S. Feu, Scott J. Hecker, Tian Qin, Donna G. Blackmond, Phil S. Baran   +7 more
openaire   +2 more sources