Results 231 to 240 of about 32,799 (288)

Soil-transmitted helminth infections among migrants and travelers: a 10-year retrospective study. [PDF]

Trop Med Health
Blazquez-Bermejo I, Salvador F, Sulleiro E, Serre-Delcor N, Martínez-Campreciós J, Aznar ML, Bosch-Nicolau P, Pou D, San José-Villar SM, Oliveira-Souto I, Molina I.   +10 more
europepmc   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth, Malte Roessing, Moritz Lehners, Lisa Dietz, Anja Schmitt, Stephan Hailfinger, Andreas Peter, Leticia Quintanilla‐Martinez, Irene Gonzalez‐Menendez, Ingmar Mederacke, German Ott, Peter Sandner, Matthias Schwab, Robert Feil, Susanne Feil   +14 more
wiley   +1 more source

The utility and use of solitary bees for pollination in greenhouses and other covered growing systems: A review. [PDF]

Curr Res Insect Sci
Hogendoorn K, Evans LJ.
europepmc   +1 more source

Optimization of novel compounds using computer‐aided drug design for treatment of cardiac arrhythmia

British Journal of Pharmacology, EarlyView.
Background and Purpose Loss‐of‐function mutations of the voltage‐gated Kv7.1 (KCNQ/KCNE1) channels lead to cardiac arrhythmia such as long QT syndrome, characterized by a prolonged QT interval . One strategy to correct the prolonged QT interval is to design molecules that activate KCNQ1/KCNE1 channels and restore the QT interval.
Jessica Jowais, Laura M. Castro‐Gonzalez, Alessia Golluscio, D. Peter Tieleman, H. Peter Larsson   +4 more
wiley   +1 more source

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

Clinical Genetics, EarlyView.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen, Karen Grønskov, Line Kessel, Sarah Linea von Holstein, Lisbeth Birk Møller, Mette Kjøbæk Gundestrup Andersen, Marianne Søndergaard Khinchi, Steffen Hamann, Marianne Wegener, Mette Bertelsen   +9 more
wiley   +1 more source

Modeling kidney fibrosis and tubular regeneration in iPSC-derived kidney organoids. [PDF]

Stem Cell Res Ther
Li S, Nlandu Q, van den Bosch TPP, Baan CC, Kramann R, Hoogduijn MJ.   +5 more
europepmc   +1 more source

Solar-driven thermochemical tri-generation of electricity, hydrogen, and green ammonia with AI-assisted triple-objective optimization. [PDF]

Sci Rep
Ayadi B, Kriaa K, Alsayah AM, Sadeq AM, Singh NSS, Aich W, Hajlaoui K, Mostafa L.   +7 more
europepmc   +1 more source

User eXperience Perception Insights Dataset (UXPID): Synthetic User Feedback from Public Industrial Forums. [PDF]

Sci Data
Kulyabin M, Joosten J, Ulan Uulu C, Martins Pacheco NM, Ries F, Petridis F, Bosch J, Olsson HH.   +7 more
europepmc   +1 more source

Palladium Porphyrin-Modified Fibrin Hydrogel for Oxygen Sensing in Engineered Skin Tissue Applications. [PDF]

ACS Omega
Matesanz A, Ruiz-Llata M, Sanz-Horta R, Bosch P, Elvira C, Reinecke H, Jorcano JL, Acedo P.   +7 more
europepmc   +1 more source

Peritoneal dialysis-induced senescence contributes to treatment failure in long-term PD. [PDF]

Sci Rep
Oberacker T, Kraft L, Pieper JM, Leibold T, Salega A, Schier R, Dong M, Balasubramanian A, Wülfrath HS, V Samson-Himmelstjerna FA, Thomsen SY, Schrumpf T, Kielstein JT, Eden G, Kolbrink B, Schulte K, Schmitt R, Latus J, Schanz M, Schricker S.   +19 more
europepmc   +1 more source