Results 41 to 50 of about 1,391 (163)
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Snakes are notable for having a broad range of predators and one of the most diverse repertoires of defensive behaviors. During heightened responses to aversive stimuli, one of the behaviors displayed is the venomous bite, particularly relevant because it triggers snakebite incidents in humans.
J. M. Alves‐Nunes +3 more
wiley +1 more source
This study sequenced and annotated the complete 17,230 bp mitochondrial genome of Ovophis makazayazaya, which contains 13 protein‐coding genes (PCGs), 2 rRNAs, 22 tRNAs, and a D‐loop region, with a significant AT bias (57.2%). Phylogenetic analyses confirmed its placement within Crotalinae, and all PCGs showed evidence of purifying selection (Ka/Ks < 1)
Yuheng Jiang, Yuhao Nie, Zhiqiang Ge
wiley +1 more source
Diet: The generalist canid exhibits a narrow niche breadth (0.12), consuming native plants (100% frequency) and animals (85%). Birds dominate animal prey (74%), peaking in the dry season, while Solanaceae plants dominate plant food (100%), peaking in the rainy season.
Aline Carneiro Veloso +4 more
wiley +1 more source
Paper electrophoretic and enzimatic studies on blood serum, venom and liver of "Bothrops jararaca"
Fígado, veneno e sôro sanguíneo de "Bothrops jararaca" foram estudados por meio da eletroforese em papel e determinação de atividades enzimáticas. Xantina oxidase e deshidrogenase foram encontradas sòmente no fígado das cobras.
Luiz P. Ribeiro +2 more
doaj +1 more source
Loss of Striatal Bradykinin B2 Receptor Alters Anxiety and Motivational Behaviors in Male Mice
Impaired signaling of the bradykinin B2 receptor (B2R) in dorsal striatal neurons decreases anxiety‐like behavior and sucrose preference while enhancing voluntary running in mice. These results reveal a novel role for B2R in dopaminergic circuits that modulate motivation and emotional behavior.
Mariana Rosolen Tavares +5 more
wiley +1 more source
Prevalence of Hepatozoon spp. (Apicomplexa, Hepatozoidae) among recently captured Brazilian snakes
The goal of this study was to determine the prevalence of Hepatozoon spp. infection in recently captured snakes from Botucatu, São Paulo State, Brazil. Blood was collected from all snakes by ventral tail venipuncture.
L.H. O'Dwyer +4 more
doaj +1 more source
Venom‐derived peptide diversity from Naja mandalayensis reveals bioactive subfractions capable of modulating neuronal oxidative stress responses. Integration of RP‐HPLC fractionation and proteomics identifies toxin families associated with improved mitochondrial function and cellular integrity in mHippoE‐18 cells, supporting venoms as a platform for ...
Brenda Rufino da Silva +3 more
wiley +1 more source
Published as part of Smith, Paul, Maciel, José, Redin Hurtado, Mikel, Galeano, Sergio, Stepan, Nicole, Brouard, Jean-Paul, Ríos, Sergio D., Ferreira Riveros, Marcela, Smith, Rebecca L., Owen, Matthew, Nicolay, Harald, Derna, Roberto, Vera Burró, Alvaro, Lahaye, Tito & Cacciali, Pier, 2024, Twenty-eight new and significant departmental reptile records ...
Smith, Paul +14 more
openaire +2 more sources
Snake envenomation is a public health problem, and while serum therapy prevents death, the local effects of venoms can lead to amputations or morbidities. Thus, alternative treatments deserve attention. In this study, we tested eight derivatives of 1,2,3-
Nayanna de Mello Amorim +7 more
doaj +1 more source

