Results 51 to 60 of about 7,760 (198)

Synthesis, characterization and utilization of a new series of 1,2,3-triazole derivatives to neutralize some toxic activities of Bothrops jararaca snake venom

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2023
Snake envenomation is a public health problem, and while serum therapy prevents death, the local effects of venoms can lead to amputations or morbidities. Thus, alternative treatments deserve attention. In this study, we tested eight derivatives of 1,2,3-
Nayanna de Mello Amorim   +7 more
doaj   +1 more source

Bothrops jararaca

open access: yes
Published as part of Smith, Paul, Maciel, José, Redin Hurtado, Mikel, Galeano, Sergio, Stepan, Nicole, Brouard, Jean-Paul, Ríos, Sergio D., Ferreira Riveros, Marcela, Smith, Rebecca L., Owen, Matthew, Nicolay, Harald, Derna, Roberto, Vera Burró, Alvaro, Lahaye, Tito & Cacciali, Pier, 2024, Twenty-eight new and significant departmental reptile records ...
Smith, Paul   +14 more
openaire   +2 more sources

Complete Mitochondrial Genome of Ovophis makazayazaya (Viperidae, Crotalinae) and Phylogenetic Analysis

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
This study sequenced and annotated the complete 17,230 bp mitochondrial genome of Ovophis makazayazaya, which contains 13 protein‐coding genes (PCGs), 2 rRNAs, 22 tRNAs, and a D‐loop region, with a significant AT bias (57.2%). Phylogenetic analyses confirmed its placement within Crotalinae, and all PCGs showed evidence of purifying selection (Ka/Ks < 1)
Yuheng Jiang, Yuhao Nie, Zhiqiang Ge
wiley   +1 more source

Generalist With a Narrow Niche Breadth: Feeding Ecology and Seed Germination Effectiveness of a Large Canid Within a Silvicultural Matrix

open access: yesAustral Ecology, Volume 51, Issue 6, June 2026.
Diet: The generalist canid exhibits a narrow niche breadth (0.12), consuming native plants (100% frequency) and animals (85%). Birds dominate animal prey (74%), peaking in the dry season, while Solanaceae plants dominate plant food (100%), peaking in the rainy season.
Aline Carneiro Veloso   +4 more
wiley   +1 more source

Structural evolution of the whole mitochondrial genome and phylogenetic inference in snakes (Squamata: Serpentes), including the undescribed mitogenome of the Brazilian endemic and critically endangered pitviper Bothrops insularis [PDF]

open access: yesGenetics and Molecular Biology
Evolutionary analyses of mitogenomes have provided insights into species evolution and conservation. Studies on snakes revealed a higher diversity especially involving variation in tRNA clusters.
Igor Salles-Oliveira   +3 more
doaj   +1 more source

Loss of Striatal Bradykinin B2 Receptor Alters Anxiety and Motivational Behaviors in Male Mice

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Impaired signaling of the bradykinin B2 receptor (B2R) in dorsal striatal neurons decreases anxiety‐like behavior and sucrose preference while enhancing voluntary running in mice. These results reveal a novel role for B2R in dopaminergic circuits that modulate motivation and emotional behavior.
Mariana Rosolen Tavares   +5 more
wiley   +1 more source

Répteis: serpentes peçonhentas: Bothrops itapetiningae

open access: yes, 2016
Apresenta a serpente jararaca (Bothrops itapetiningae (Squamata: Viperidae))Componente Curricular::Ensino Médio::BiologiaComponente Curricular::Educação Superior::Ciências Biológicas::Biologia GeralComponente Curricular::Educação Superior::Ciências ...
Sebben, Antonio
core   +1 more source

Discovery of Neuroprotective Venom‐Derived Candidates From Naja Mandalayensis in mHippoE‐18 Cells Via Fractionation and Proteomic Mapping

open access: yesChemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Venom‐derived peptide diversity from Naja mandalayensis reveals bioactive subfractions capable of modulating neuronal oxidative stress responses. Integration of RP‐HPLC fractionation and proteomics identifies toxin families associated with improved mitochondrial function and cellular integrity in mHippoE‐18 cells, supporting venoms as a platform for ...
Brenda Rufino da Silva   +3 more
wiley   +1 more source

Snake Venom Protease Detection and Inhibition in Serum

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
A fluorescence assay enables sensitive detection of the activities of snake venom metalloproteases (SVMP) and serine proteases (SVSP) from viper venoms in buffer and serum. In combination with effective low‐molecular‐weight inhibitors such as ilomastat and nafamostat, this approach offers new prospects for the rapid diagnosis and adjunctive therapy of ...
Mareike Riedel, Christian Kersten
wiley   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar   +2 more
wiley   +1 more source

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