Vascular Aging in the Invertebrate Chordate, Botryllus schlosseri [PDF]
Vascular diseases affect over 1 billion people worldwide and are highly prevalent among the elderly, due to a progressive deterioration of the structure of vascular cells.
Delany Rodriguez +6 more
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The genome sequence of the colonial chordate, Botryllus schlosseri [PDF]
Botryllus schlosseri is a colonial urochordate that follows the chordate plan of development following sexual reproduction, but invokes a stem cell-mediated budding program during subsequent rounds of asexual reproduction.
Ayelet Voskoboynik +18 more
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New Data on the Rhamnose-Binding Lectin from the Colonial Ascidian Botryllus schlosseri: Subcellular Distribution, Secretion Mode and Effects on the Cyclical Generation Change [PDF]
Botryllus schlosseri in a cosmopolitan ascidian, considered a reliable model organism for studies on the evolution of the immune system. B. schlosseri rhamnose-binding lectin (BsRBL) is synthesised by circulating phagocytes and behaves as an opsonin by ...
Giacomo Bovo, Loriano Ballarin
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Botryllus schlosseri as a Unique Colonial Chordate Model for the Study and Modulation of Innate Immune Activity [PDF]
Understanding the mechanisms that sustain immunological nonreactivity is essential for maintaining tissue in syngeneic and allogeneic settings, such as transplantation and pregnancy tolerance.
Oron Goldstein +7 more
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Botryllin, a Novel Antimicrobial Peptide from the Colonial Ascidian Botryllus schlosseri [PDF]
By mining the transcriptome of the colonial ascidian Botryllus schlosseri, we identified a transcript for a novel styelin-like antimicrobial peptide, which we named botryllin.
Nicola Franchi +2 more
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The Onset of Whole-Body Regeneration in Botryllus schlosseri: Morphological and Molecular Characterization [PDF]
Colonial tunicates are the only chordates that regularly regenerate a fully functional whole body as part of their asexual life cycle, starting from specific epithelia and/or mesenchymal cells.
Lorenzo Ricci +8 more
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Data on four apoptosis-related genes in the colonial tunicate Botryllus schlosseri [PDF]
The data described are related to the article entitled “Recurrent phagocytosis-induced apoptosis in the cyclical generation change of the compound ascidian Botryllus schlosseri” (Franchi et al., 2016) [1].
Nicola Franchi +4 more
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Yamanaka Factors in the Budding Tunicate Botryllus schlosseri Show a Shared Spatio-Temporal Expression Pattern in Chordates [PDF]
In vertebrates, the four transcription factors Sox2, c-Myc, Pou5f1 and Klf4 are involved in the differentiation of several tissues during vertebrate embryogenesis; moreover, they are normally co-expressed in embryonic stem cells and play roles in ...
Virginia Vanni +9 more
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Ontology for the asexual development and anatomy of the colonial chordate Botryllus schlosseri. [PDF]
Ontologies provide an important resource to integrate information. For developmental biology and comparative anatomy studies, ontologies of a species are used to formalize and annotate data that are related to anatomical structures, their lineage and ...
Lucia Manni +7 more
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Multi-omics analysis reveals important role for microbial-derived metabolites from Botryllus schlosseri in metal interactions [PDF]
Marine microbial communities govern many of the biological and chemical processes in the ocean, including element cycles, ecosystem health, and disease.
Dulce G. Guillén Matus +8 more
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