The
Background Allorecognition, the ability of an organism to distinguish self from non-self, occurs throughout the entire tree of life. Despite the prevalence and importance of allorecognition systems, the genetic basis of allorecognition has rarely been ...
Nydam Marie L, De Tomaso Anthony W
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Improved Media Formulations for Primary Cell Cultures Derived from a Colonial Urochordate [PDF]
The cultivation of marine invertebrate cells in vitro has garnered significant attention due to the availability of diverse cell types and cellular potentialities in comparison to vertebrates and particularly in response to the demand for a multitude of ...
Andy Qarri +4 more
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Insights into the Complement System of Tunicates: C3a/C5aR of the Colonial Ascidian Botryllus schlosseri [PDF]
As an evolutionary ancient component of the metazoan immune defense toolkit, the complement system can modulate cells and humoral responses of both innate and (in jawed vertebrates) adaptive immunity.
Anna Peronato +2 more
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Historical navigation routes in European waters leave their footprint on the contemporary seascape genetics of a colonial urochordate [PDF]
Humans have intensively sailed the Mediterranean and European Atlantic waters throughout history, from the upper Paleolithic until today and centuries of human seafaring have established complex coastal and cross-seas navigation networks.
Eitan Reem +2 more
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Temporally and spatially dynamic germ cell niches in Botryllus schlosseri revealed by expression of a TGF-beta family ligand and vasa [PDF]
Background Germ cells are specified during early development and are responsible for generating gametes in the adult. After germ cells are specified, they typically migrate to a particular niche in the organism where they reside for the remainder of its ...
Adam D. Langenbacher +1 more
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Origin and Dispersal History of Two Colonial Ascidian Clades in the Botryllus schlosseri Species Complex. [PDF]
Human-induced global warming and species introductions are rapidly altering the composition and functioning of Earth's marine ecosystems. Ascidians (Phylum Chordata, Subphylum Tunicata, Class Ascidiacea) are likely to play an increasingly greater role in
Marie L Nydam +2 more
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Speed vs completeness: a comparative study of solitary and colonial tunicate embryogenesis [PDF]
Solitary ascidians, such as Ciona robusta, have been used for over a century as model systems for embryological studies. These species are oviparous, producing many relatively small and transparent eggs, which are released and fertilized outside the ...
Chiara Anselmi +7 more
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Proteome-Wide 4-Hydroxy-2-Nonenal Signature of Oxidative Stress in the Marine Invasive Tunicate Botryllus schlosseri. [PDF]
ABSTRACT The ascidian Boytryllus schlosseri is a marine chordate that thrives under conditions of anthropogenic climate change. The B. schlosseri expressed proteome contains unusually high levels of proteins adducted with 4‐hydroxy‐2‐nonenal (HNE). HNE represents a prominent posttranslational modification resulting from oxidative stress.
Kültz D +6 more
europepmc +2 more sources
New data on C1qDC from the colonial ascidian Botryllus schlosseri
In the compound ascidian Botryllus schlosseri, we recently identified a novel C1q-domain-containing (C1qDC) protein expressed by circulating immunocytes, called BsC1qDC.
A Peronato +3 more
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Botryllus schlosseri allorecognition: tackling the enigma. [PDF]
Allorecognition has been well-studied in the context of vertebrate adaptive immunity and recognition of the Major Histocompatibility Complex (MHC), which is the central event of vertebrate immune responses. Although allorecognition systems have been identified throughout the metazoa, recent results have shown that there is no apparent conservation or ...
Taketa DA, De Tomaso AW.
europepmc +6 more sources

