Results 81 to 90 of about 11,850,269 (338)
, 2016 The seabed morphology, type of sediments, and dominant benthic species on eleven mud volcanoes and diapirs located on the northern sector of the Gulf of Cadiz continental slope have been studied.
D. Palomino +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Strongly-Interacting Heavy Flavors Beyond the Standard Model [PDF]
, 2000 The origin of mass must lie in physics beyond the Standard Model. Dynamical electroweak symmetry breaking models like technicolor can generate masses for the W and Z bosons.
Simmons, Elizabeth H.
core +3 more sources
Current effects on scattering of surface gravity waves by bottom topography
, 2005 Scattering of random surface gravity waves by small amplitude topography in the presence of a uniform current is investigated theoretically. This problem is relevant to ocean waves propagation on shallow continental shelves where tidal currents are often
Ardhuin, Fabrice, Magne, Rudy
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Erosion and deposition in interplain channels of the Maury channel system [PDF]
, 1981 Large turbidity currents originating on the insular margin of southern lceland have flowed clown a 2 500 km-long pathway comprising rise valleys, unchanneled plains and segments of erosional and depositional deep-sea channels that are collectively called
Hollister, C. D. +2 more
core +1 more source
Seasonal sediment dynamics on the Barcelona inner shelf (NW Mediterranean): a small Mediterranean river- and wave-dominated system [PDF]
, 2017 The seasonal pattern of sediment dynamics on an inner shelf characterized by the presence of sediment delivered by a small, mountainous river (with a “flash-flood” regime) was investigated. Near-bottom suspended sediment fluxes across the shelf (i.e. 20,
Grifoll Colls, Manel +3 more
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Flow of Antarctic Bottom water from the Vema Channel
Geoscience Letters, 2020 We analyze measurements of bottom currents and thermohaline properties of water north of the Vema Channel with the goal to find pathway continuations of Antarctic Bottom Water flow from the Vema Channel into the Brazil Basin. The analysis is based on CTD/
Eugene G. Morozov +2 more
doaj +1 more source