Results 91 to 100 of about 19,548 (244)

Pain trajectories in children and adolescents with cerebral palsy: A longitudinal population‐based register study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Four pain trajectories were identified in a population‐based register study of 4887 children and adolescents with cerebral palsy: (1) increasing trend, low probability of experiencing pain (20.28%), (2) increasing trend, high probability of experiencing pain (30.30%), (3) decreasing trend (26.85%), and (4) consistently high probability of experiencing ...
May Phyu Sin   +3 more
wiley   +1 more source

A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]

open access: yes, 2008
Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Bal Ram Singh   +6 more
core   +1 more source

Pseudo‐Dystonic Gait in a Preschool Child: Foot Posturing Contralateral to a Cuboid Fracture

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Allison J. Chirigos   +4 more
wiley   +1 more source

Acceptability of Atropine Eyedrops Administered Sublingually for Sialorrhea Treatment Related to Neurological Conditions

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Off‐label use of anticholinergic agents (atropine eye drops) administered sublingually are a first‐line treatment in standard clinical practice in France to treat sialorrhea in patients with neurological conditions. The ability and willingness to using and administering such medication have become key factors to ensure safe and effective ...
Hugues Michelon   +6 more
wiley   +1 more source

An Ultrasensitive Gold Nanoparticle-based Lateral Flow Test for the Detection of Active Botulinum Neurotoxin Type A

open access: yesNanoscale Research Letters, 2017
Botulism is a severe and potentially lethal paralytic disease caused by several botulinum neurotoxin-producing Clostridia spp. In China, the majority of the cases caused by botulism were from less-developed rural areas.
Jing Liu   +10 more
doaj   +1 more source

Emerging Treatments for Erectile Dysfunction

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent condition that can significantly affect men's sexual health and quality of life, and for which there are many well‐studied effective treatments. In spite of this, many individuals still seek out alternative therapies.
Resa Magill   +3 more
wiley   +1 more source

Electrochemical impedance spectroscopy biosensor for detection of active botulinum neurotoxin

open access: yesSensing and Bio-Sensing Research, 2014
The standard method for the detection of botulinum neurotoxin is currently the mouse bioassay which is considered to be the most reliable method for the detection of the active form of this toxin.
Jennifer Halliwell   +3 more
doaj   +1 more source

Botulinum neurotoxins are zinc proteins.

open access: yesJournal of Biological Chemistry, 1992
The available amino acid sequences of 150-kDa botulinum and tetanus neurotoxins show the presence of a closely homologous segment in the middle of the light chain (NH2-terminal 50 kDa), which is the intracellularly active portion of the toxin. This segment contains the zinc binding motif of metalloendopeptidases, HEXXH.
Schiavo G.   +4 more
openaire   +4 more sources

Asymmetric Upper Limb Dysfunction Demonstrated at the Bedside: A Phenomenology Video

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Gero Lueg   +4 more
wiley   +1 more source

Three‐year outcomes of repeated botulinum neurotoxin A injections to the lower extremities in young children with spastic cerebral palsy in GMFCS levels I to III

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 6, Page 792-799, June 2026.
In this study, we followed a group of children 2 to 6 years old with spastic cerebral palsy functioning in GMFCS levels I–III, over 3 years. Sixty‐five received BoNT‐A and 59 did not. Repeated BoNT‐A injections over 3 years were not associated with improvements in gross motor function or passive ankle dorsiflexion. Daily step counts, favouring the BoNT‐
Darcy Fehlings   +11 more
wiley   +1 more source

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