Results 111 to 120 of about 19,548 (244)

Type E Botulinum Neurotoxin-Producing Clostridium butyricum Strains Are Aerotolerant during Vegetative Growth

mSystems, 2019
Clostridium butyricum, the type species of the genus Clostridium, is considered an obligate anaerobe, yet it has been shown to grow in the presence of oxygen. C. butyricum strains atypically producing the botulinum neurotoxin type E are the leading cause
Serena Camerini, Lucia Marcocci, Lara Picarazzi, Egidio Iorio, Irene Ruspantini, Paola Pietrangeli, Marco Crescenzi, Giovanna Franciosa   +7 more
doaj   +1 more source

Fragment C of Tetanus Toxin : New Insights into Its Neuronal Signaling Pathway [PDF]

, 2012
When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
Acheson, Aguilera, Ana C. Calvo, Anderson, Barati, Boquet, Borasio, Bordet, Brooks, Calappi, Carlton, Chaib-Oukadour, Chaib-Oukadour, Check, Chen, Chen, Ciriza, Coen, Conway, Cosman, Cowie, Deinhardt, Deinhardt, Deinhardt, Emsley, Evinger, Firor, Fishman, Flexner, Fotinou, Gil, Gil, Gil, Gil, Habermann, Habermann, Harvey, Helting, Herreros, Herreros, Humeau, Inserte, Ipsen, Jayaraman, Jayaraman, Johnson, Johnson, Johnson, José Aguilera, Lalli, Landsteiner, Larsen, Lazarovici, Louch, Manning, Manwaring, Martini, Mendieta, Menestrina, Miana-Mena, Miana-Mena, Miana-Mena, Mochida, Montal, Moreno-Igoa, Moreno-Igoa, Neubauer, Noguchi, Oliveira, Pelliccioni, Pellizari, Pilar Zaragoza, Raquel Manzano, Roaf, Rosario Osta, Roux, Rummel, Sara Oliván, Sherrington, Siade, Simpson, Sinha, Skaper, Skeldal, Sugiyama, Sutton, Thorne, Twiss, Ungar, Van Heyningen, Van Heyningen, Van Heyningen, Van Heyningen, Wang, Wassermann, Wright   +95 more
core   +3 more sources

Combined Use of Botulinum Toxin A and Profhilo for Upper Face Rejuvenation: A Randomized Clinical Trial

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Hyaluronic acid (HA) and Botulinum toxin A (BTX‐A) treatments are highly regarded for their effectiveness in facial rejuvenation. Aim To investigate whether adding Profhilo enhances the effects of BTX‐A for frontal skin rejuvenation.
Zahra Saffarian, Amirhossein Rahimnia, Ala Ehsani, Kamran Balighi, Amirhoushang Ehsani, Zahra Razavi, Mina Koohian Mohammadabadi, Faezeh khorasanizadeh, Ghazal Ghaffarzadeh, Parvaneh Hatami   +9 more
wiley   +1 more source

An Investigation of Immunogenicity of Chitosan-Based Botulinum Neurotoxin E Binding Domain Recombinant Candidate Vaccine via Mucosal Route

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017
Background and Objectives: Botulism syndrome is caused by serotypes A-G of neurotoxins of Clostridium genus. Neurotoxin binding domain is an appropriate vaccine candidate due to its immunogenic activity.
Mohammad Javad Bagheripour, Firouz Ebrahim, Abbas Hajizadeh, Shahram Nazarian, Jamil Zargan, Jamal Rashidiani   +5 more
doaj  

Protocol and Demographics of the RELY-CD Study: Assessing Long-Term Clinical Response to Botulinum Neurotoxin in Cervical Dystonia

Toxins
The RELY-CD study investigated the long-term clinical response to botulinum neurotoxin type A in cervical dystonia within a multicenter, real-world setting.
Benjamin Waeschle, John-Ih Lee, Tristan Kölsche, Robin Jansen, Marta Banach, Stanislaw Ochudlo, Małgorzata Tyślerowicz, Piotr Sobolewski, Sara Sánchez Valiente, Eva López-Valdés, Pablo Mir, Silvia Jesús, Elena Ojeda-Lepe, Ewa Papuć, Pilar Sánchez Alonso, Gabriel Salazar, Georg Comes, Holger Stark, Philipp Albrecht   +18 more
doaj   +1 more source

Long-term efficacy of botulinum toxin A for treatment of blepharospasm,hemifacial spasm, and spastic entropion: a multicentre study using two drug-dose escalation indexes [PDF]

, 2010
PURPOSE: To investigate the long-term effectiveness and safety of botulinum neurotoxin A (BoNT-A) treatment in patients with blepharospasm (BEB), hemifacial spasm (HFS), and entropion (EN) and to use for the first time two modified indexes, 'botulin ...
A Berardelli, A Casuccio, A Cetinkaya, A Neetens, A Wang, AB Scott, AB Scott, AL Pang, B Wabbels, BR Frueh, C Kenney, D Dressler, D Truong, DA Cohen, DH Steel, DM Simpson, DM Yoshimura, EM Helveston, Epidemiological Study of Dystonia in Europe (ESDE) Collaborative Group, F Di Pace, F Grandas, F Micheli, G Cossu, G Defazio, G Defazio, G Raimondi, GT Drummond, J Carruthers, J Jankovic, J Jankovic, J Reimer, JA Mauriello, JA Mauriello, JD Porter, JD Taylor, JJ Dutton, JJ Dutton, JJ Dutton, JJ Dutton, JL Vitek, JR Ainsworth, JR Clarke, JS Elston, JS Elston, M Cillino, M Flanders, M Hallett, M Snir, MZ Atassi, N Guépratte, P Calace, P Greene, P Roggenkämper, PF Engstrom, RG Auger, RL Anderson, RL Levy, RM Siatkowski, RS Gonnering, S Cillino, S Damiani, S Jitpimolmard, S Mercadante, S Ochudlo, SS Lowe, Subcommittee of the American Academy of Neurology, T Vogt, W Huang   +67 more
core   +1 more source

Effects of Pallidal Deep Brain Stimulation on Speech and Swallowing in Pediatric Patients with Dystonia

Movement Disorders Clinical Practice, Volume 13, Issue 5, Page 1194-1205, May 2026.
Abstract Background Bilateral globus pallidus internus deep brain stimulation (GPi‐DBS) is a proven safe and effective treatment in certain forms of idiopathic or inherited dystonia (ID/IN). Its effects in acquired dystonia such as in dyskinetic cerebral palsy (DCP) however vary widely.
Katerina Bernardi, Andrea A. Kühn, Ana Luísa de Almeida Marcelino, Matthias Eckenweiler, Cornelia Rensing‐Zimmermann, Joachim K. Krauss, Joachim Runge, Rene Marquez Franco, Delia Lorenz, Monika Müller, Alfons Schnitzler, Andrea Bevot, Lidwin von Spee, Veerle Visser‐Vandewalle, Lars Timmermann, Petra Schiller, Anne Koy   +16 more
wiley   +1 more source

Spore Germination Apparatus in Clostridium botulinum Group I and II [PDF]

, 2017
Spore germination is a significant step in the transformation of dormant spores into exponentially dividing vegetative cells, and in the case of Clostridium botulinum in the formation of the deadly botulinum neurotoxin.
Pye, Hannah
core  

Observational Evaluation of Muscle Echointensity and EMG Insertional Activity in Poststroke Spasticity

Muscle &Nerve, Volume 73, Issue 5, Page 858-866, May 2026.
ABSTRACT Introduction/Aims When spasticity occurs after a stroke, peripheral changes in spastic muscle architecture may develop. The primary objective was to determine if an association exists between spastic muscle echointensity (EI) measured by the Modified Heckmatt Scale (MHS) and changes in insertional activity detected by electromyography (EMG ...
Rajiv Reebye, Ève Boissonnault, April Jeon, Mirko Filippetti, Gina McKernan, Oluwasanmi O. Adenaiye, Alessandro Picelli, Michael C. Munin   +7 more
wiley   +1 more source

Neurotropic Effect of Botulinum Toxin and the Potential of Specific Serum Therapy in Botulism (Review)

Безопасность и риск фармакотерапии
INTRODUCTION. The outbreak of foodborne botulism that occurred in Russia in June 2024 once again demonstrated the danger of this rather rare but severe infectious disease caused by ingesting botulinum neurotoxin.
E. M. Eliseeva, I. A. Mazerkina, A. A. Chistokhina   +2 more
doaj   +1 more source