Results 131 to 140 of about 83,600 (312)
mSystems, 2019 Clostridium butyricum, the type species of the genus Clostridium, is considered an obligate anaerobe, yet it has been shown to grow in the presence of oxygen. C. butyricum strains atypically producing the botulinum neurotoxin type E are the leading cause
Serena Camerini +7 more
doaj +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley +1 more source
Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors
Nature Communications, 2017 Botulinum neurotoxin B is a Food and Drug Administration-approved therapeutic toxin. However, it has lower binding affinity toward the human version of its major receptor, synaptotagmin II (h-Syt II), compared to mouse Syt II, because of a residue ...
Liang Tao +12 more
semanticscholar +1 more source
Biosecurity Threat Posed by Botulinum Toxin
Toxins, 2019 The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as ...
Orlando Cenciarelli +2 more
doaj +1 more source
Reduction in Post-Botulinum Toxin Flu-like Symptoms After Injection with Incobotulinum Toxin [PDF]
, 2014 OBJECTIVE: To determine if patients reporting flu-like symptoms (FLS) after botulinum toxin (BoNT) injections are less susceptible to this reaction after incobotulinum toxin.
George, Edwin, Shneyder, Natalya
core +1 more source
Wound botulism in injectors of drugs: upsurge in cases in England during 2004. [PDF]
, 2005 Wound infections due to Clostridium botulinum were not recognised in the UK and Republic of Ireland before 2000. C. botulinum produces a potent neurotoxin which can cause paralysis and death. In 2000 and 2001, ten cases were clinically recognised, with a
Akbulut, D +10 more
core +1 more source
Artificial Organs, EarlyView.People with spinal cord injury (SCI) experience bladder overactivity, which can cause incontinence. Dorsal genital nerve stimulation (DGNS) can suppress overactivity, providing a longer duration to reach a toilet. People with SCI trialed home‐based DGNS for 8 weeks. DGNS was effective in the laboratory, and participants found home‐based DGNS acceptable.
Sean Doherty +4 more
wiley +1 more source
Nature Communications, 2017 A short half-life in the circulation limits the application of therapeutics such as single-domain antibodies (VHHs). We utilize red blood cells to prolong the circulatory half-life of VHHs.
Nai-Jia Huang +8 more
semanticscholar +1 more source
Electrochemical impedance spectroscopy biosensor for detection of active botulinum neurotoxin
Sensing and Bio-Sensing Research, 2014 The standard method for the detection of botulinum neurotoxin is currently the mouse bioassay which is considered to be the most reliable method for the detection of the active form of this toxin.
Jennifer Halliwell +3 more
doaj +1 more source
Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić +6 more
wiley +1 more source