Results 161 to 170 of about 83,600 (312)

Glycopyrronium 320 μg/mL in children and adolescents with severe sialorrhoea and neurodisabilities: An open‐label study extension of the SALIVA trial

Developmental Medicine &Child Neurology, Volume 67, Issue 8, Page 1085-1094, August 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16268 Abstract Aims To test the long‐term efficacy, safety, and impact on quality of life (QoL) of an oral paediatric formulation of 320 μg/mL glycopyrronium in the 36‐week SALIVA (Sialanar plus orAl rehabiLitation against placebo plus oral rehabilitation for chIldren and ...
Pierre Fayoux, Mickael Dinomais, Helen Shaw, Frédéric Villain, Déborah Schwartz, Vincent Gautheron, Guy Letellier, Stéphane Auvin   +7 more
wiley   +1 more source

The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene [PDF]

, 1990
D.E. Thompson, John K. Brehm, John D. Oultram, Tracy‐Jane SWINFIELD, Clifford C. Shone, Tony Atkinson, J. Melling, Nigel P. Minton   +7 more
openalex   +1 more source

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash, Joseph Tam, Osnat Rosen, Hermona Soreq   +3 more
wiley   +1 more source

Single Application of A2 NTX, a Botulinum Toxin A2 Subunit, Prevents Chronic Pain Over Long Periods in Both Diabetic and Spinal Cord Injury–Induced Neuropathic Pain Models

Journal of Pharmacological Sciences, 2012
Botulinum toxin type A is a unique candidate for inhibition of pain transmission. In the present study we attempted to see the beneficial actions of A2 neurotoxin (NTX), an active subunit of botulinum toxin type A.
Lin Ma, Jun Nagai, Yuki Sekino, Yoshitaka Goto, Shinji Nakahira, Hiroshi Ueda   +5 more
doaj  

Sequence of the gene encoding type F neurotoxin of Clostridium botulinum [PDF]

, 1992
Alison K. East
openalex   +1 more source

A Novel Peel to Prevent Post‐Inflammatory Hyperpigmentation After CO2 Resurfacing for Acne Scars

Journal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Atrophic acne scars are a common dermatological concern, often requiring fractional carbon dioxide (CO2) laser resurfacing for effective treatment. However, in darker skin types (Fitzpatrick III–V), the high risk of post‐inflammatory hyperpigmentation (PIH) remains a significant limitation, affecting treatment outcomes.
Xiaozhun Hang, Davin Sui Lim
wiley   +1 more source

Simple Method for Detection of Clostridium botulinum Type A to F Neurotoxin Genes by Ploymerase Chain Reaction [PDF]

, 1996
Kouichi Takeshi, Yukako Fujinaga, Kaoru Inoue, Hiroshi Nakajima, Keiji Oguma, Tetsuya Ueno, Hiroyuki Sunagawa, Tohru Ohyama   +7 more
openalex   +1 more source

Efficacy of Botulinum Toxin A for the Management of Melasma: A Split‐Face, Randomized Control Study

Journal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Melasma management remains challenging due to its multifactorial nature pathogenesis and recurrent nature. Previous studies showed positive effects of botulinum toxin A (BoNT‐A) for treating and preventing ultraviolet‐induced hyperpigmentation.
Sasipim Chaijaras, Suphagan Boonpethkaew, Sonphet Chirasuthat, Nawara Sakpuwadol, Tanat Yongpisarn, Pimsiri Anansiripun, Vasanop Vachiramon   +6 more
wiley   +1 more source

Structural stabilization of botulinum neurotoxins by tyrosine phosphorylation [PDF]

, 1998
José Antonio Encinar, Asia Fernández‐Carvajal, José A. Ferragut, José M. González‐Ros, Bibhuti R. DasGupta, M Montal, Antonio Ferrer-Montiel   +6 more
openalex   +1 more source

Profile of Xeomin® (incobotulinumtoxinA) for the treatment of blepharospasm

Clinical Ophthalmology, 2011
Juwan Park1, Michael S Lee2, Andrew R Harrison31Department of Ophthalmology, The Catholic University of Korea, Seoul, Korea; 2Department of Ophthalmology, Neurology and Neurosurgery, 3Department of Ophthalmology and Otolaryngology, University of ...
Park J, Lee MS, Harrison AR
doaj