Blepharospasm in GNAO1 Syndrome May Benefit From Botulinum Toxins
Movement Disorders Clinical Practice, EarlyView.
Eleonora Minacapilli +4 more
wiley +1 more source
Applications of Artificial Intelligence in Neurological Voice Disorders
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Neurological voice disorders, such as Parkinson's disease, laryngeal dystonia, and stroke‐induced dysarthria, significantly impact speech production and communication. Traditional diagnostic methods rely on subjective assessment, whereas artificial intelligence (AI) offers objective, noninvasive, and scalable solutions for voice analysis. This
Dongren Yao +2 more
wiley +1 more source
Amantadine Can Treat Blepharospasm in Levodopa Peak‐Dose Dyskinesia
Movement Disorders Clinical Practice, EarlyView.
Francisco de Assis Aquino Gondim +4 more
wiley +1 more source
Artificial Organs, EarlyView.People with spinal cord injury (SCI) experience bladder overactivity, which can cause incontinence. Dorsal genital nerve stimulation (DGNS) can suppress overactivity, providing a longer duration to reach a toilet. People with SCI trialed home‐based DGNS for 8 weeks. DGNS was effective in the laboratory, and participants found home‐based DGNS acceptable.
Sean Doherty +4 more
wiley +1 more source
Use of Immunofluorescence and Animal Tests to Detect Growth and Toxin Production by Clostridium botulinum Type E in Food [PDF]
, 1968 T. F. Midura +4 more
openalex +1 more source
Artificial Organs, EarlyView.TESCS‐ABT induced neurophysiological changes in individuals with chronic complete SCI, however these did not consistently translate into functional improvements. These findings highlight the role of residual supraspinal connectivity and inform future research to optimise this neurotechnology for SCI rehabilitation and identify likely responders ...
E. L. McNicol +6 more
wiley +1 more source
Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins. [PDF]
, 2020 Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed. Single-domain antibodies (VHH) have been examined as a countermeasure for BoNT because of their high ...
Jin, Rongsheng +8 more
core
Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić +6 more
wiley +1 more source
Botulinum toxin treatment of spasticity in diplegic cerebral palsy : a randomised, double-blind, placebo-controlled, dose-ranging study [PDF]
This study evaluated the efficacy and safety of three doses of botulinum toxin A (BTX-A; Dysport®) in 125 patients (mean age 5.2 years, SD 2; 54% male)with dynamic equinus spasticity during walking. Participants were randomized to receive Dysport (10,
Bakheit +32 more
core +1 more source
Kinetics of the Thermal Inactivation of Type E Clostridium botulinum Toxin [PDF]
, 1967 J. J. Licciardello +3 more
openalex +1 more source