Results 131 to 140 of about 182,114 (282)

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao   +3 more
wiley   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

open access: yesPhytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao   +11 more
wiley   +1 more source

From Toxin to Treatment: A Narrative Review on the Use of Botulinum Toxin for Autonomic Dysfunction

open access: yesToxins
Since its regulatory approval over a half-century ago, botulinum toxin has evolved from one of the most potent neurotoxins known to becoming routinely adopted in clinical practice.
Lucas Rempel   +5 more
doaj   +1 more source

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan   +2 more
wiley   +1 more source

Review of botulinum toxin type A for the prophylactic treatment of chronic daily headache

open access: yes, 2007
Stefan EversDepartment of Neurology, University of Münster, Münster, GermanyAbstract: Botulinum toxin A is increasingly used in the treatment of idiopathic and symptomatic headache disorders.
Stefan Evers
core  

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li   +12 more
wiley   +1 more source

Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity

open access: yes, 2016
Michelle Kaku, David M Simpson Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA Abstract: Poststroke spasticity affects up to one-half of stroke patients and has debilitating effects, contributing to diminished ...
Simpson DM, Kaku M
core  

Secondary nonresponsiveness to new bulk botulinum toxin A (BCB2024)

open access: yes, 2002
We report on a patient with cranio-cervical dystonia injected with the new, lower protein formulation of botulinum toxin A who developed secondary resistance to this toxin.
Perlmutter, Joel S   +2 more
core   +1 more source

Outcomes of Long‐Term Absorbable Mesh Use for Ventral Hernia Repair in Immunosuppressed Patients

open access: yesWorld Journal of Surgery, EarlyView.
Immunosuppressed patients are more at risk of perioperative infections. In case of ventral hernia repair, the use of a long‐term absorbable mesh could potentially decrease the infectious risk in these patients. This study aimed to assess the short‐ and mid‐term outcomes of ventral hernia repair with long‐term absorbable mesh in immunosuppressed and non‐
Gaëtan‐Romain Joliat   +2 more
wiley   +1 more source

A Case Report of Herpes Zoster After Botulinum Toxin Injections [PDF]

open access: yes
Shadi Zari Department of Dermatology, College of Medicine, University of Jeddah, Jeddah, Saudi ArabiaCorrespondence: Shadi Zari, Department of Dermatology, College of Medicine, University of Jeddah, Saudi Arabia, Email Shadizarimd@gmail.comAbstract: This
Zari S
core  

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