Results 141 to 150 of about 182,114 (282)
ANZ Journal of Surgery, EarlyView.ABSTRACT Background The choice of anastomotic technique in minimally invasive oesophagectomy (MIO) may influence postoperative morbidity and long‐term outcomes. The primary aim of our study is to determine whether circular (CS) or linear‐stapled (LS) anastomosis is associated with anastomotic complications following MIO.
L. Vu +5 more
wiley +1 more source
Roux‐en‐Y Reconstruction After Esophagectomy for Postoperative Functional Complaints: A Case Series
ANZ Journal of Surgery, EarlyView.Functional complaints affect half of esophagectomy patients, with no standard treatment. In nine patients, Roux‐en‐Y reconstruction for obstruction, redundant conduit, and weight loss was safely performed, with one major complication and no Grade 4 out of five events. Complete symptom resolution reached 67% at 3 months and 89% at 1 year.
Donika Zogaj +6 more
wiley +1 more source
Pathophysiology of Delayed Gastric Conduit Emptying After Oesophagectomy: A Multicentre Cohort Study
ANZ Journal of Surgery, EarlyView.In this multicentre study of 272 patients, early and late delayed gastric conduit emptying after oesophagectomy emerged as distinct phenotypes. Early DGCE was predicted by open surgery, whereas late DGCE was predicted by GOJ tumour location and postoperative complications.
Jonathan Sivakumar +10 more
wiley +1 more source
Third‐Line Overactive Bladder Treatments: Cost–Benefit Analysis in an Australian Public Hospital
ANZ Journal of Surgery, EarlyView.ABSTRACT Introduction and Objectives To review the efficacy and cost‐effectiveness of third‐line overactive bladder (OAB) managements, including percutaneous tibial nerve stimulation (PTNS), intravesical botulinum toxin A (Botox) and sacral neuromodulation (SNM) in the urology department of a tertiary public hospital.
Rowan Klein Nulend +4 more
wiley +1 more source
Botulinum Toxin Off-Label Use in Dermatology: A Review
, 2017 Botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It is currently used for aesthetic treatments and in the focal hyperhidrosis.
CAMPANATI, Anna +11 more
core +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
PLoS ONEPurposeThis study aimed to assess the efficacy of botulinum toxin type A in treating childhood-acquired comitant esotropia and identify predictive factors of treatment success.MethodsThis retrospective, consecutive, non-comparative cohort study included ...
Narisa Rattanalert +6 more
doaj +1 more source
Targeting KRAS for cancer therapy
British Journal of Pharmacology, EarlyView.In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia +4 more
wiley +1 more source
Cholinergic inputs to motoneurons in the spinal cord augment focal muscle spasticity in rodents
British Journal of Pharmacology, EarlyView.Background and Purpose Cholinergic premotor inputs to motoneurons support high levels of motor output when required. However, the possible role of these inputs in pathologically elevated muscle tone has not been characterised. To address this, we examined the modulatory effect of spinal acetylcholine (ACh) on experimental spastic paralysis ...
Patrik Meglić +10 more
wiley +1 more source