Results 161 to 170 of about 35,819 (219)
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Critical Care Clinics, 2005
Botulinum toxin is regarded as the most lethal substance known. It is estimated that the human LD50 for inhalation botulism is 1 to 3 nanograms of toxin/kilogram body mass. Although only three cases of inhalational botulism have been described, an understanding of the pathophysiology of food-borne outbreaks, wound botulism, and infant botulism, and ...
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Botulinum toxin is regarded as the most lethal substance known. It is estimated that the human LD50 for inhalation botulism is 1 to 3 nanograms of toxin/kilogram body mass. Although only three cases of inhalational botulism have been described, an understanding of the pathophysiology of food-borne outbreaks, wound botulism, and infant botulism, and ...
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Pharmacology of botulinum toxin
Journal of the American Academy of Dermatology, 2000Botulinum toxin has a well-defined role among dermatologists for the treatment of facial wrinkling, brow position, and palmar and axillary hyperhidrosis.The purpose of this study is to educate dermatologists on the pharmacology of botulinum toxin.A retrospective review of the literature on botulinum toxin from 1962 to the present was conducted.
W, Huang, J A, Foster, A S, Rogachefsky
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Dermatologic Surgery, 2000
Botulinum toxin has been used successfully for the treatment of hyperfunctional facial lines.To determine the alteration in brow position after botulinum toxin treatment of the brow depressor muscles.Eleven women, 30-60 years old, were treated. Prior to treatment, brow position was measured relative to the pupil.
W, Huang, A S, Rogachefsky, J A, Foster
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Botulinum toxin has been used successfully for the treatment of hyperfunctional facial lines.To determine the alteration in brow position after botulinum toxin treatment of the brow depressor muscles.Eleven women, 30-60 years old, were treated. Prior to treatment, brow position was measured relative to the pupil.
W, Huang, A S, Rogachefsky, J A, Foster
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Innovation in Botulinum Toxins
Dermatologic ClinicsThis study aims to analyze and discuss recent trials of high-dose and liquid toxins for treating moderate to severe glabellar lines. A comprehensive review of clinical studies and patient outcomes data was conducted to assess the effectiveness and safety profiles of high-dose and liquid toxins.
Reema, Rashied, Michael H, Gold
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Botulinum Toxin in Ophthalmology
Survey of Ophthalmology, 2007Since its introduction into clinical medicine in 1980, botulinum toxin has become a major therapeutic drug with applications valuable to many medical sub-specialties. Its use was spearheaded in ophthalmology where its potential applications have expanded to cover a broad range of visually related disorders.
Jonathan J, Dutton, Amy M, Fowler
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American Journal of Physical Medicine & Rehabilitation, 2004
In the United States, the popularity of botulinum toxins as agents to treat muscle hypertonia has grown significantly over the last decade, despite lack of approval from the Food and Drug Administration for the indication of spasticity. Botox (botulinum toxin type A) and Myobloc (botulinum toxin type B) are Food and Drug Administration-approved for ...
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In the United States, the popularity of botulinum toxins as agents to treat muscle hypertonia has grown significantly over the last decade, despite lack of approval from the Food and Drug Administration for the indication of spasticity. Botox (botulinum toxin type A) and Myobloc (botulinum toxin type B) are Food and Drug Administration-approved for ...
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Current Allergy and Asthma Reports, 2016
Rhinitis is a common clinical entity. Besides nasal obstruction, itching, and sneezing, one of the most important symptoms of rhinitis is nasal hypersecretion produced by nasal glands and exudate from the nasal vascular bed. Allergic rhinitis is an IgE-mediated inflammatory reaction of nasal mucosa after exposure to environmental allergens.
Cengiz, Ozcan, Onur, Ismi
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Rhinitis is a common clinical entity. Besides nasal obstruction, itching, and sneezing, one of the most important symptoms of rhinitis is nasal hypersecretion produced by nasal glands and exudate from the nasal vascular bed. Allergic rhinitis is an IgE-mediated inflammatory reaction of nasal mucosa after exposure to environmental allergens.
Cengiz, Ozcan, Onur, Ismi
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Botulinum Toxin in Otorhinolaryngology
2014Through its anticholinergic effect, botulinum toxin is a suitable therapeutic option for dysfunctions of the muscular and the autonomic nervous system.Beside the classical indications like facial hyperkinesis (i.e. blepharospasm, hemifacial spasm), the treatment of complex dystonias (oromandibular dystonia, spasmodic dystonia, cervical dystonia ...
S, Rohrbach, R, Laskawi
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2020
This chapter is focused on analgesic mechanism of action of botulinum toxin type A (BoNT-A) including the action beyond peripheral nerve endings. With the exception of the meninges and possibly urinary bladder, the presence of BoNT-A activity in the periphery, cleaving SNAP25 as a target molecule, up to now was not convincingly shown.
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This chapter is focused on analgesic mechanism of action of botulinum toxin type A (BoNT-A) including the action beyond peripheral nerve endings. With the exception of the meninges and possibly urinary bladder, the presence of BoNT-A activity in the periphery, cleaving SNAP25 as a target molecule, up to now was not convincingly shown.
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International Journal of Food Microbiology, 1990
Abstract Structure, activation, destruction, lethality, genesis, neurotoxic action and medical application of botulinal toxins are reviewed.
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Abstract Structure, activation, destruction, lethality, genesis, neurotoxic action and medical application of botulinal toxins are reviewed.
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