Results 51 to 60 of about 182,114 (282)

Intra-sphincteric botulinum toxin in the management of functional biliary pain

Endoscopy International Open, 2022
Background and study aims The management of functional biliary-type pain remains a clinical challenge. Intra sphincteric botulinum toxin putatively exerts an anti-spasmodic and anti-nociceptive effect.
Shyam Menon, Andrew Holt, Adam D. Farmer
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Weller, U., Nordmann, J. J., Dayanithi, G., Ahnert-Hilger, G., Lnk, H., Gratzl, Manfred   +5 more
core   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

Facial Cosmetic Therapy Use Among Patients With Systemic Sclerosis: An Australian Cohort Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is associated with numerous facial manifestations for which patients may engage in cosmetic therapies. It is unclear how patients with SSc use these therapies. This study sought to characterize patient engagement and experiences with cosmetic therapies for SSc‐related and non‐SSc–related facial changes.
Zachary Warren, Diane Apostolopoulos, Gene‐Siew Ngian, Amanda M. Saracino, Laura Ross, Nava Ferdowsi, Jennifer Walker, Cindy Hall, Kim Griggs, Susanna Proudman, Wendy Stevens, Joanne Sahhar   +11 more
wiley   +1 more source

High‐Density Magnetomyography With Optical Magnetometers Reveals Spatiotemporal Patterns of Evoked Muscle Activity

Advanced Materials Technologies, EarlyView.
Optically pumped magnetometers are employed to contactlessly map the spatiotemporal dynamics of the magnetic field linked to electrical activity of a skeletal muscle in vivo. It is demonstrated that localization of the clinically relevant innervation zone is feasible using this non‐invasive magnetic measurement modality. ABSTRACT Magnetomyography (MMG)
Simon Nordenström, Victor Lebedev, Stefan Hartwig, Marlen Kruse, Santiago Rodriguez, Lukas Baier, Nima Noury, Thomas Klotz, Ahmet Doğukan Keleş, Justus Marquetand, Markus Siegel, Oliver Röhrle, Thomas Middelmann   +12 more
wiley   +1 more source

Treatment of acute acquired concomitant esotropia

BMC Ophthalmology, 2021
Background The treatment efficacy of botulinum toxin bilateral medial rectus injections for acute acquired concomitant esotropia (AACE) in adult is not clear.
Minghua Shi, Yuanxiang Zhou, Aijiao Qin, Jing Cheng, Hongxing Ren   +4 more
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Immunogenicity of botulinum toxins [PDF]

Journal of Neural Transmission, 2012
Botulinum neurotoxins are formulated biologic pharmaceuticals used therapeutically to treat a wide variety of chronic conditions, with varying governmental approvals by country. Some of these disorders include cervical dystonia, post-stroke spasticity, blepharospasm, migraine, and hyperhidrosis.
Naumann, Markus, Boo, Lee Ming, Ackerman, Alan H., Gallagher, Conor J.   +3 more
openaire   +3 more sources

Complications of botulinum toxin for cosmetic indications

, 2023
<p>Botulinum toxin has become a popular tool in aesthetic medicine, offering effective solutions for the management of facial wrinkles. However, as its use has proliferated, concerns over complications have also arisen.
Aldair Romero López M.D., Esperanza Guadalupe Carlock Gallegos M.D., Jorge Eduardo Barragán Morales M.D, Aleyois Benítez Moreno M.D., Dariana Martínez Marabotto M.D., Elizbeth Durán Junco M.D., Mariana Méndez Torruco M.D.   +6 more
core   +1 more source