Results 41 to 50 of about 172,004 (307)

New technology to improve the thermal stability of botulinum toxin type D by biomimetic mineralization

Scientific Reports, 2021
The advanced biomimetic mineralization technology was applied to protect the Botulinum neurotoxin type D, and the processing of the mineralization granule of botulinum toxin type D was successfully screened.
Shengqing Li, Xiyun Zhang, Guoyuan Hu, Shuping Li, Zhining Li, Yuxia Fan, Yanming Zhang   +6 more
doaj   +1 more source

Botulinum Toxin A for the Treatment of Keloids [PDF]

, 2012
Introduction: Keloids are the result of excessive scar tissue formation. Besides their poor aesthetic appearance, keloids can be associated with severe clinical symptoms such as pain, itching, and rigidity.
Bureik, D., Schauber, J, Ruzicka, T, Gauglitz, Gerd, Dombrowski, Yvonne, Pavicic, T., Pavicic, T, Ruzicka, Thomas, Gauglitz, G G, Schauber, Jürgen, Dombrowski, Y; id_orcid, Bureik, D   +11 more
core   +1 more source

Botulinum toxin type A in treatment of chronic migraine, spasticity and bruxism

Journal of Education, Health and Sport, 2023
Introduction: Nowadays, botulinum toxin has found use in many disease entities such as chronic migraine, spasticity, bruxism and many others. Among serotypes A-E, type A is mainly used in treatment.
Klaudia Kuliga, Katarzyna Dobko, Gabriela Frącz, Agata Glac, Kinga Musz, Natalia Sejnowska, Agnieszka Socha, Agata Surowiec, Kinga Śnieżek, Anna Zając   +9 more
doaj   +1 more source

Diffusion of Botulinum Toxins

Tremor and Other Hyperkinetic Movements, 2012
Background: It is generally agreed that diffusion of botulinum toxin occurs, but the extent of the spread and its clinical importance are disputed. Many factors have been suggested to play a role but which have the most clinical relevance is a subject of much discussion.
Brodsky, Matthew A., Swope, David M., Grimes, David   +2 more
openaire   +5 more sources

Development of a technique for DNA detection and identification of toxigenic strains of Clostridium botulinum types A, B, E by the Real-Time PCR method

Вестник войск РХБ защиты, 2023
Botulism is dangerous toxic infection caused by a toxin produced by the bacterium Clostridium botulinum. The mortality rate from botulism can reach 70% of all cases of illness in case of untimely initiation of treatment.
D. S. Yanov, A. V. Kuznetsovskiy, M. I. Dubrovin, A. V. Mironin, N. V. Onuchina, A. V. Filippov   +5 more
doaj   +1 more source

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Weller, U., Nordmann, J. J., Dayanithi, G., Ahnert-Hilger, G., Lnk, H., Gratzl, Manfred   +5 more
core   +1 more source

The Structure and Classification of Botulinum Toxins

, 2021
Botulinum neurotoxins (BoNTs) are a family of bacterial protein toxins produced by various Clostridium species. They are traditionally classified into seven major serotypes (BoNT/A-G).
Stenmark, Pål,, Dong, Min,, Lund University.   +2 more
core   +1 more source

Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]

, 1994
The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Weller, U., Dayanithi, G., Yamasaki, S., Niemann, H., Gratzl, Manfred, Stecher, B., Höhne-Zell, B., Binz, T.   +7 more
core   +1 more source

Arrangement of the Clostridium baratii F7 toxin gene cluster with identification of a σ factor that recognizes the botulinum toxin gene cluster promoters.

PLoS ONE, 2014
Botulinum neurotoxin (BoNT) is the most poisonous substances known and its eight toxin types (A to H) are distinguished by the inability of polyclonal antibodies that neutralize one toxin type to neutralize any of the other seven toxin types.
Nir Dover, Jason R Barash, Julianne N Burke, Karen K Hill, John C Detter, Stephen S Arnon   +5 more
doaj   +1 more source

Tetanus: Pathophysiology, Treatment, and the Possibility of Using Botulinum Toxin against Tetanus-Induced Rigidity and Spasms

Toxins, 2013
Tetanus toxin, the product of Clostridium tetani, is the cause of tetanus symptoms. Tetanus toxin is taken up into terminals of lower motor neurons and transported axonally to the spinal cord and/or brainstem. Here the toxin moves trans-synaptically into
Bjørnar Hassel
doaj   +1 more source