Results 181 to 190 of about 2,612,022 (237)

Enolase and 16.5‐kDa Tegument‐Associated Protein in Fasciola hepatica Extracellular Vesicles: Clues to Their Role in Pathogenesis

open access: yesJournal of Extracellular Biology, Volume 4, Issue 6, June 2025.
Recombinant enolase and 16.5 tegumentary proteins from F. hepatica EVs may influence the progression of fibrosis, altering cell growth, proteomic profiles, and EVs secretion in macrophages, hepatic stellate cells (HSCs) and hepatocytes. r‐Fhenolase reduced fibrosis markers in HSCs and exhibited anti‐inflammatory properties in macrophages, and r‐Fh16 ...
Aránzazu González‐Arce   +4 more
wiley   +1 more source

The Interconnected World of Dermatology and Ophthalmology

open access: yesJEADV Clinical Practice, Volume 4, Issue 2, Page 389-399, June 2025.
Medical science, is an integrated field that shares intricate relationship between various organ systems. Similarly, dermatology is inter‐related with various other specialties including ophthalmology. This article depicts the correlation of ophthalmology and dermatology iterating on the genetic diseases, autoimmune diseases, systemic disorders ...
Gyanesh Rathore   +4 more
wiley   +1 more source

Exploration of Neurodegenerative Diseases Using Long‐Read Sequencing and Optical Genome Mapping Technologies

open access: yesMovement Disorders, Volume 40, Issue 6, Page 996-1008, June 2025.
Abstract Genetic factors play a central role in neurodegenerative disorders. Over the past few decades, significant progress has been made in identifying the causative genes of numerous monogenic disorders, largely due to the widespread adoption of next‐generation sequencing (NGS) technologies in both research and clinical settings.
Guillaume Cogan   +4 more
wiley   +1 more source

Motor Cortex Disinhibition Correlates with Olfactory Dysfunction in Parkinson's Disease

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1085-1097, June 2025.
Abstract Background Motor cortex disinhibition, as measured by impaired short‐interval intracortical inhibition (SICI) using transcranial magnetic stimulation (TMS), is a well‐established feature of Parkinson's disease (PD). However, its substantial variability among patients remains unexplained, prompting questions about its origin, clinical relevance,
Claudia Ammann   +12 more
wiley   +1 more source

Novel In‐Frame FGF14 Deletion Causes Spinocerebellar Ataxia Type 27A: Clinical Response to Deep Brain Stimulation and 4‐Aminopyridine

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1182-1188, June 2025.
Abstract Background Spinocerebellar ataxia 27A (SCA27A) is a rare neurodegenerative disorder characterized by childhood‐onset tremor and progressive cerebellar dysfunction. SCA27A is usually caused by loss‐of‐function FGF14 variants. Objectives We report the identification of a novel FGF14 variant in a five‐generation family with autosomal dominant ...
Ignacio J. Keller Sarmiento   +6 more
wiley   +1 more source

The Effect of Corticosteroid Doses on Pain in Knee Osteoarthritis: A Systematic Review and Meta‐Analysis

open access: yesMusculoskeletal Care, Volume 23, Issue 2, June 2025.
ABSTRACT Objective To evaluate the effect of various doses of intra articular corticosteroid injection (IACI) on pain reduction in knee osteoarthritis when compared with normal saline and perform a between‐dose comparison. Methods A systematic review with meta‐analysis was conducted searching four databases until April 2024.
Marc‐Antoine Lafrenaye‐Dugas   +3 more
wiley   +1 more source

Prevalence of function‐limiting late effects in survivors of head and neck cancer

open access: yesPM&R, Volume 17, Issue 6, Page 654-662, June 2025.
Abstract Background Survivors of head and neck cancer (HNC) are commonly affected by multiple complex and interrelated long‐term and late effects that can adversely affect their function and quality of life. Objective To define the prevalence of neuromuscular, musculoskeletal, visceral, oncologic, and other late effects affecting function and quality ...
Yu Hui Won, Michael D. Stubblefield
wiley   +1 more source

Comparison of the effects of occlusal splint and Botox injections on the amount of mouth opening and chronic pain in individuals with temporomandibular disorders: a systematic review and meta‐analysis

open access: yesAustralian Dental Journal, Volume 70, Issue 2, Page 132-140, June 2025.
Abstract Objective This systematic review and meta‐analysis study was carried out to compare the effectiveness of occlusal splint (OS) and Botox (BTX) injections in temporomandibular disorders (TMDs). Material and Methods Irrespective of the starting year, studies were searched for up to 2024 using PubMed, Web of Science, Scopus databases and the ...
Ö İşisağ, H Atasoy, S Yıldız
wiley   +1 more source

CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation

open access: yesActa Ophthalmologica, Volume 103, Issue 4, Page e240-e255, June 2025.
Abstract The 5th CORONIS Symposium, held during the 2023 Congress of the European Association for Vision and Eye Research (EVER), highlighted the growing importance of ocular surface innervation in eye surface disorders. This article summarises the insights and perspectives shared during the symposium, which focused on the clinical relevance of ocular ...
Anat Galor   +10 more
wiley   +1 more source

Long‐term urinary outcomes in classic bladder exstrophy: results of an extensive follow‐up

open access: yesBJU International, Volume 135, Issue 6, Page 1018-1024, June 2025.
Objectives To evaluate long‐term outcomes and predictive factors of urinary continence (UC) and fecal continence (FC) after surgery for classic bladder exstrophy (CBE) using validated questionnaires. Patients and Methods This study is part of the QUALEXSTRO study, a retrospective, observational, single‐centre cohort study assessing through ...
Sarah Abdellaoui   +7 more
wiley   +1 more source

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