Results 71 to 80 of about 16,551 (199)

Long‐term cost‐effectiveness of invasive urodynamic studies for overactive bladder in women

BJU International, EarlyView.
Objectives To estimate the cost‐effectiveness of using invasive urodynamic studies (UDS) in the management of women with refractory overactive bladder (OAB) symptoms using the results of the FUTURE trial. Patients and Methods The FUTURE study is the largest randomised controlled trial evaluating the clinical effectiveness of UDS with comprehensive ...
Helen Bell‐Gorrod, Praveen Thokala, Suzanne Breeman, David Cooper, Graeme MacLennan, Mohamed Abdel‐Fattah, Simon Dixon   +6 more
wiley   +1 more source

Botulinum toxin therapy: functional silencing of salivary disorders. [PDF]

, 2017
Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary ...
Lovato, A, Marchese Ragona, R., Marioni, Gino, Ottaviano, Giancarlo, Restivo, Da   +4 more
core  

Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris. [PDF]

, 2005
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Ellar, David J, Gurkan, Cemal
core   +2 more sources

P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho‐GTPase‐dependent motility that requires an interaction with P2Y1 receptors

British Journal of Pharmacology, EarlyView.
Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain, Dingxin Pan, Kate L. Arkless, Khondaker Miraz Rahman, Clive P. Page, Kalwant S. Authi, Simon C. Pitchford   +6 more
wiley   +1 more source

Peroral endoscopic myotomy in spastic esophageal disorders: Clinical outcomes and optimal approaches

Digestive Endoscopy, EarlyView.
Objectives The efficacy and safety of peroral endoscopic myotomy (POEM) for spastic esophageal disorders (SED), including type III achalasia, distal esophageal spasm (DES), and jackhammer esophagus (JE), remain uncertain due to its rarity. This study aimed to evaluate the clinical outcomes and optimal strategies for managing SED.
Tetsuya Tatsuta, Haruhiro Inoue, Yuto Shimamura, Miyuki Iwasaki, Kei Ushikubo, Kazuki Yamamoto, Yohei Nishikawa, Hidenori Tanaka, Ippei Tanaka, Satoshi Abiko, Mayo Tanabe, Kazuya Sumi, Manabu Onimaru, Boldbaatar Gantuya, Hirotake Sakuraba, Shinsaku Fukuda   +15 more
wiley   +1 more source

Negative effects on oral motor function after submandibular and parotid botulinum neurotoxin A injections for drooling in children with developmental disabilities

Developmental Medicine &Child Neurology, Volume 67, Issue 5, Page 656-664, May 2025.
Graphical representation of the research objective, methodology, key findings, and implications. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16171 Abstract Aim To evaluate negative effects on oral motor function after concurrent submandibular and parotid (four‐gland) botulinum neurotoxin A (BoNT‐A) injections as a treatment
Reva M. van Eck, Lynn B. Orriëns, Corinne P. A. Delsing, Frank J. A. van den Hoogen, Corrie E. Erasmus, Karen van Hulst   +5 more
wiley   +1 more source

Glycopyrronium 320 μg/mL in children and adolescents with severe sialorrhoea and neurodisabilities: An open‐label study extension of the SALIVA trial

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16268 Abstract Aims To test the long‐term efficacy, safety, and impact on quality of life (QoL) of an oral paediatric formulation of 320 μg/mL glycopyrronium in the 36‐week SALIVA (Sialanar plus orAl rehabiLitation against placebo plus oral rehabilitation for chIldren and ...
Pierre Fayoux, Mickael Dinomais, Helen Shaw, Frédéric Villain, Déborah Schwartz, Vincent Gautheron, Guy Letellier, Stéphane Auvin   +7 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

The Journal of Dermatology, EarlyView.
Yoshihide Asano, Jun Asai, Takayuki Ishii, Yohei Iwata, Masanari Kodera, Chie Miyabe, Akihiko Uchiyama, Youichi Ogawa, Ken Okamura, Mari Kishibe, Yuta Koike, Yorihisa Kotobuki, Noriki Fujimoto, Takuya Miyagi, Yukie Yamaguchi, Ayumi Yoshizaki, Reiko Omori, Takeshi Nakanishi, Hiroshi Fujiwara, Takeo Maekawa, Sei‐ichiro Motegi, Yuichiro Yoshino, Minoru Hasegawa, Manabu Fujimoto, Takao Tachibana, Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee (connective tissue disease/vasculitis group)   +27 more
wiley   +1 more source

Serial correlation between saliva and blood beta‐hydroxybutyrate levels in children commencing the ketogenic diet for epilepsy

Epilepsia, EarlyView.
Abstract Objectives Accurate and user‐friendly methods to measure beta‐hydroxybutyrate (BHB) concentration are needed to guide the optimal use of ketogenic diet therapy (KDT). We aimed to determine the correlation between serum, capillary, and salivary BHB concentration, and to validate an electrochemical salivary BHB point‐of‐care test (POCT) in ...
Neha Kaul, Jing Duan, Dong Cui, Michael Erlichster, Zhibin Chen, Dovile Anderson, Jianxiong Chan, Ingrid E. Scheffer, Efstratios Skafidas, Jianxiang Liao, Patrick Kwan   +10 more
wiley   +1 more source

Botulinum toxin type A treatment for a parotid gland injury in two adult horses

Equine Veterinary Education, EarlyView.
Summary The most common disorder affecting the salivary glands in horses is trauma to the parotid gland or duct. Several management techniques have been described, each with their own set of complications. The objective of this case report was to describe the direct injection of botulinum toxin type A into the parotid gland and its outcome in two ...
C. Jimenez, F. Comino, D. Gorvy
wiley   +1 more source