Results 71 to 80 of about 18,175 (274)
Structure of dual receptor binding to botulinum neurotoxin B [PDF]
, 2014 Botulinum neurotoxins are highly toxic, and bind two receptors to achieve their high affinity and specificity for neurons. Here we present the first structure of a botulinum neurotoxin bound to both its receptors.
Berntsson, Ronnie P-A +3 more
core +1 more source
Automated Creak Identifies Laryngeal Dystonia During Conversational Speech
The Laryngoscope, EarlyView.This study evaluated whether automated creak distinguished speakers with adductor laryngeal dystonia (AdLD), muscle tension dysphonia (MTD), and those without voice disorders during conversational speech. Automated creak estimates were able to differentiate speakers with AdLD from MTD and controls with similar performance across different types of ...
Daria A. Dragicevic +13 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy +7 more
wiley +1 more source
Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris. [PDF]
, 2005 RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Ellar, David J, Gurkan, Cemal
core +2 more sources
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Background Energy‐based treatments for atrophic acne scars (AAS) in darker skin phototypes must balance efficacy with pigmentary safety. While the nonablative 675‐nm laser has shown promise with minimal risk of adverse effects, prospective data in Asian populations remain limited.
Pinthisa Nisagornsen +6 more
wiley +1 more source
Expression, Purification and evaluation of the Immunogenicity of RecombinantC-terminus of the Receptor-Binding Domain of Neurotoxin Botulinum Protein Type B (BoNT/B-HcC) [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2023 Background and Aim: Botulism, a syndrome caused by food poisoning, results from use of food contaminated with the botulinum toxin, which is very dangerous and deadly.
Hossein Samiei Abianeh +5 more
doaj
Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins. [PDF]
, 2020 Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed. Single-domain antibodies (VHH) have been examined as a countermeasure for BoNT because of their high ...
Jin, Rongsheng +8 more
core
Botulinum Toxin Efficacy in Upper Limb Tremor: A Systematic Review and Meta‐Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background Essential tremor (ET) and dystonic tremor syndrome (DTS) can be treated using botulinum toxin (BoNT) injections. Previous reviews lacked an assessment of the certainty of evidence and focused solely on clinician‐reported outcomes. Additionally, studies have demonstrated interindividual variability in BoNT efficacy. Objective The aim
Iris M. Visser +5 more
wiley +1 more source
Primary treatment of early fistula of parotid duct with botulinum toxin type A injection [PDF]
Anais Brasileiros de Dermatologia, 2017 : Salivary duct injury can be idiopathic, iatrogenic, or post-trauma and may result in sialocele or fistula. Most injuries regress spontaneously and botulinum toxin A is one of several therapeutic possibilities.
Camila Ferron +3 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel +5 more
wiley +1 more source