Results 91 to 100 of about 43,287 (326)

Fragment C of Tetanus Toxin : New Insights into Its Neuronal Signaling Pathway [PDF]

, 2012
When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
Acheson, Aguilera, Ana C. Calvo, Anderson, Barati, Boquet, Borasio, Bordet, Brooks, Calappi, Carlton, Chaib-Oukadour, Chaib-Oukadour, Check, Chen, Chen, Ciriza, Coen, Conway, Cosman, Cowie, Deinhardt, Deinhardt, Deinhardt, Emsley, Evinger, Firor, Fishman, Flexner, Fotinou, Gil, Gil, Gil, Gil, Habermann, Habermann, Harvey, Helting, Herreros, Herreros, Humeau, Inserte, Ipsen, Jayaraman, Jayaraman, Johnson, Johnson, Johnson, José Aguilera, Lalli, Landsteiner, Larsen, Lazarovici, Louch, Manning, Manwaring, Martini, Mendieta, Menestrina, Miana-Mena, Miana-Mena, Miana-Mena, Mochida, Montal, Moreno-Igoa, Moreno-Igoa, Neubauer, Noguchi, Oliveira, Pelliccioni, Pellizari, Pilar Zaragoza, Raquel Manzano, Roaf, Rosario Osta, Roux, Rummel, Sara Oliván, Sherrington, Siade, Simpson, Sinha, Skaper, Skeldal, Sugiyama, Sutton, Thorne, Twiss, Ungar, Van Heyningen, Van Heyningen, Van Heyningen, Van Heyningen, Wang, Wassermann, Wright   +95 more
core   +3 more sources

Widespread Sequence Variations in VAMP1 across Vertebrates Suggest a Potential Selective Pressure from Botulinum Neurotoxins [PDF]

, 2014
Botulinum neurotoxins (BoNT/A-G), the most potent toxins known, act by cleaving three SNARE proteins required for synaptic vesicle exocytosis. Previous studies on BoNTs have generally utilized the major SNARE homologues expressed in brain (VAMP2 ...
Adler, Michael, Borrell, Andrew, Demogines, Ann, Dong, Min, Johnson, Eric A., Liu, Huisheng, Peng, Lisheng, Sawyer, Sara L., Tao, Liang, Tepp, William H., Zhang, Su-Chun   +10 more
core   +3 more sources

On Botulinum Neurotoxin Variability

mBio, 2015
The rapidly growing number of botulinum neurotoxin sequences poses the problem of the possible evolutionary significance of the variability of these superpotent neurotoxins for toxin-producing Clostridium species. To progress in the understanding of this
Cesare Montecucco, Maria Berica Rasotto
doaj   +1 more source

Clinical Algorithm‐Guided Approach to Botulinum Toxin Type A Treatment for Axial Postural Abnormalities in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Axial postural abnormalities (APAs) are common, disabling complications of Parkinson's disease (PD) with unclear pathophysiology. The presence of hyperactivity in multiple trunk muscles supports the use of botulinum toxin (BTA). However, its application is complex, due to the lack of standardized clinical and electrophysiological ...
Giacomo Argenziano, Giovanna Squintani, Serena Camozzi, Ilaria Di Vico, Marialuisa Gandolfi, Carlo Alberto Artusi, Michele Tinazzi, Christian Geroin   +7 more
wiley   +1 more source

Proteomic Methods of Detection and Quantification of Protein Toxins

Toxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova, Jana Klimentova, Alena Fucikova, Jiri Dresler   +3 more
doaj   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Cosmetic Effect of Botulinum Toxin In Focal Hyperhydrosis

Annals of Indian Academy of Neurology, 2005
Hyperhydrosis of axillae, palm and sole is not a very uncommon problem. It leads to great embarrassment and considerable emotional stress to the individuals.
Jain S, Tamer SK, Hiran S, Dwivedi M D
doaj  

Characterization of Hemagglutinin Negative Botulinum Progenitor Toxins

Toxins, 2017
Botulism is a disease involving intoxication with botulinum neurotoxins (BoNTs), toxic proteins produced by Clostridium botulinum and other clostridia. The 150 kDa neurotoxin is produced in conjunction with other proteins to form the botulinum progenitor
Suzanne R. Kalb, Jakub Baudys, Theresa J. Smith, Leonard A. Smith, John R. Barr   +4 more
doaj   +1 more source

Introduction to the Toxins Special Issue on Botulinum Toxins: New Uses in the Treatment of Diseases. [PDF]

Toxins (Basel), 2023
Luvisetto S.
europepmc   +1 more source

H17: Botulinum toxin: from lethal adversary to dermatological sensation – how the power of poison was harnessed [PDF]

, 2022

openalex   +1 more source