Results 91 to 100 of about 311,527 (352)

A Randomized, Double‐Blind, Placebo Controlled, Crossover Trial of incobotulinumtoxinA Treatment for Upper Limb Tremor

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Proximal upper limb tremor is a common, functionally disabling condition. Medical therapy is often ineffective. IncobotulinumtoxinA can significantly improve tremor with minimal adverse effects. Objectives We aimed to compare clinical, functional, and quality of life measures in patients with proximal upper limb tremor following ...
Sai A. Nagaratnam   +10 more
wiley   +1 more source

Low-Dose Pre-Operative Botulinum Toxin A Effectively Facilitates Complex Ventral Hernia Repair: A Case Report and Review of the Literature

open access: yesMedicina, 2020
Background: Complex ventral hernias following laparotomy present a unique challenge in that repair is hindered by the lateral tension of the abdominal wall. A novel approach to overcome this is the “chemical component separation” technique.
Ali P. Mourad   +2 more
doaj   +1 more source

Botulinum Toxin-A in Dystonia

open access: yesPediatric Neurology Briefs, 1990
A report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology concludes that local injection of type A botulinum toxin (Botox) is proven as a safe and efficacious modality for the treatment of blepharospasm, cervical dystonia, and hemifacial spasm.
openaire   +3 more sources

Recombinant rabies virus particles presenting botulinum neurotoxin antigens elicit a protective humoral response in vivo

open access: yesMolecular Therapy: Methods & Clinical Development, 2014
Botulinum neurotoxins are one of the most potent toxins found in nature, with broad medical applications from cosmetics to the treatment of various neuropathies.
Andrew W Hudacek   +6 more
doaj   +1 more source

Long‐Term Safety and Efficacy of Repeat Treatments with DaxibotulinumtoxinA in Cervical Dystonia: Results from the ASPEN‐Open‐Label Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background DaxibotulinumtoxinA (DAXI), a novel botulinum neurotoxin (BoNT) formulation, was shown to be safe, effective, and long‐lasting in the treatment of cervical dystonia (CD) over one treatment cycle in the phase 3, randomized, placebo‐controlled ASPEN‐1 trial.
Peter McAllister   +11 more
wiley   +1 more source

A case of infant botulism in a 4-month-old baby [PDF]

open access: yes, 2016
This case-report highlights: i) the difficulty of IB diagnosis as it is a rare syndrome with subclinical onset, ii) the need for an accurate training for physicians involved in IB management, iii) the efficacy and safety of TEqA in IB treatment, iv ...
Bruna Auricchio   +6 more
core   +1 more source

Safety and Efficacy of 10 kHz Spinal Cord Stimulation for the Treatment of Refractory Chronic Migraine: A Prospective Long‐Term Open‐Label Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy   +7 more
wiley   +1 more source

Proteomic Methods of Detection and Quantification of Protein Toxins

open access: yesToxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova   +3 more
doaj   +1 more source

Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris. [PDF]

open access: yes, 2005
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Ellar, David J, Gurkan, Cemal
core   +2 more sources

Computer Vision Technologies in Movement Disorders: A Systematic Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Evaluation of movement disorders primarily relies on phenomenology. Despite refinements in diagnostic criteria, the accuracy remains suboptimal. Such a gap may be bridged by machine learning and video technology, which permit objective, quantitative, non‐invasive motor analysis.
Pasquale Maria Pecoraro   +4 more
wiley   +1 more source

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