Results 101 to 110 of about 311,527 (352)

On Botulinum Neurotoxin Variability

mBio, 2015
The rapidly growing number of botulinum neurotoxin sequences poses the problem of the possible evolutionary significance of the variability of these superpotent neurotoxins for toxin-producing Clostridium species. To progress in the understanding of this
Cesare Montecucco, Maria Berica Rasotto
doaj   +1 more source

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources

Reading Difficulty of Online Patient Education Materials for Procedures in Dermatology

JEADV Clinical Practice, EarlyView.
Elizabeth Botto, Nicole Natarelli, Emily Coughlin, Lilia Correa‐Selm   +3 more
wiley   +1 more source

Characterization of Hemagglutinin Negative Botulinum Progenitor Toxins

Toxins, 2017
Botulism is a disease involving intoxication with botulinum neurotoxins (BoNTs), toxic proteins produced by Clostridium botulinum and other clostridia. The 150 kDa neurotoxin is produced in conjunction with other proteins to form the botulinum progenitor
Suzanne R. Kalb, Jakub Baudys, Theresa J. Smith, Leonard A. Smith, John R. Barr   +4 more
doaj   +1 more source

A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]

, 2020
Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan, Franc, Nathalie C, Guichard, Annabel, Roy, Sitara, Schwartz, Ruth   +4 more
core  

Functional Head Tremor: Contrasting Features with Other Tremor Etiologies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Functional tremor (FT) is considered the most common phenomenology among patients with functional movement disorders (FMDs). Most patients have limb tremor, but they can also present with tremor involving the head and trunk. Objectives and Methods We aimed to assess the clinical phenomenology of functional head tremor (FHT) and ...
José Fidel Baizabal‐Carvallo, Joseph Jankovic   +1 more
wiley   +1 more source

A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]

, 2008
Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Bal Ram Singh, Dan Li, James Keller, Michael Adler, Peng Zhang, Prabhati Ray, Radharaman Ray   +6 more
core   +1 more source

Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains. [PDF]

, 2016
Clostridium sporogenes is a non-pathogenic close relative and surrogate for Group I (proteolytic) neurotoxin-producing Clostridium botulinum strains.
Bullough, Per A., Fagan, Robert P., Hobbs, Jamie K., Janganan, Thamarai K., Moir, Anne, Mullin, Nic, Stringer, Sandra, Tzokov, Svetomir B.   +7 more
core   +2 more sources

The Effect of Intragastric Administration of Botulinum Toxin Type A on Reducing Adiposity in a Rat Model of Obesity Using Micro-CT and Histological Examinations

Gut and Liver, 2017
Background/AimsBotulinum toxin type A (BTX), a long-acting inhibitor of muscular contraction in both striated and smooth muscles, is responsible for gastric motility.
Jin-Seok Park, Hong-Mei Zheng, Jae-Min Kim, Chung Sei Kim, Seok Jeong, Don Haeng Lee   +5 more
doaj   +1 more source

Introduction to the Toxins Special Issue on Botulinum Toxins: New Uses in the Treatment of Diseases. [PDF]

Toxins (Basel), 2023
Luvisetto S.
europepmc   +1 more source