Results 121 to 130 of about 119,004 (251)

Recombinant synthesis and immunological characterization of single-domain antibodies against botulinum neurotoxin serotype A and B

Tạp chí Kiểm nghiệm và An toàn thực phẩm
Nanobodies which are single-domain antibodies derived from the Variable Heavy domain of Heavy-chain-only antibodies (VHHs) found in camels and sharks, represent a novel approach for enhancing the detection and neutralization of food toxins.
Luong Trung Hieu, Bui Thi Thu Hoai, Phan Thi Thanh Thuy, Nguyen Le Duc Hai, Nguyen Thi Anh Nguyet, Pham Bao Yen, Nguyen Thi Hong Loan, Phan Tuan Nghia, Nguyen Thanh Trung, Le Phuong Linh, Trinh Van Toan, Le Thi Hong Nhung   +11 more
doaj   +1 more source

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan, Qiu‐Rong Yang, Pei‐Yun Zhuang   +2 more
wiley   +1 more source

Gut mucin fucosylation dictates the entry of botulinum toxin complexes

Nature Communications
Botulinum toxins (BoNTs) produced by Clostridium botulinum are the most potent known bacterial toxins. The BoNT complex from serotype B-Okra (LPTC/BOkra) exerts at least 80-fold higher oral toxicity in mice compared with that from serotype A1 (L-PTC/A62A)
Sho Amatsu, Takuhiro Matsumura, Chiyono Morimoto, Sunanda Keisham, Yoshiyuki Goto, Tomoko Kohda, Jun Hirabayashi, Kengo Kitadokoro, Takane Katayama, Hiroshi Kiyono, Hiroaki Tateno, Masahiko Zuka, Yukako Fujinaga   +12 more
doaj   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Characterisation of botulinum toxins type A and B, by matrix-assisted laser desorption ionisation and electrospray mass spectrometry

, 2002
A method earlier developed for the mass spectrometric (MS) identification of tetanus toxin (TTx) was applied to botulinum toxins type A and B (BTxA and BTxB).
Baar, B.L.M. van, Jong, A.L. de, Hulst, A.G., Wils, E.R.J.   +3 more
core  

Outcomes of Long‐Term Absorbable Mesh Use for Ventral Hernia Repair in Immunosuppressed Patients

World Journal of Surgery, EarlyView.
Immunosuppressed patients are more at risk of perioperative infections. In case of ventral hernia repair, the use of a long‐term absorbable mesh could potentially decrease the infectious risk in these patients. This study aimed to assess the short‐ and mid‐term outcomes of ventral hernia repair with long‐term absorbable mesh in immunosuppressed and non‐
Gaëtan‐Romain Joliat, Benoit Romain, Guillaume Passot   +2 more
wiley   +1 more source

Botulinum toxins for dystonia

, 2020
RESUMEN La toxina botulínica es actualmente en tratamiento de elección para las distonía focales y algunos segmentos del cuerpo en casos de distonía generalizada.
Moreno López, Claudia Lucía, Cerquera Cleves, Catalina   +1 more
core   +1 more source

Botulinum toxins for dystonia [PDF]

, 2017
RESUMEN La toxina botulínica es actualmente en tratamiento de elección para las distonía focales y algunos segmentos del cuerpo en casos de distonía generalizada.
Moreno López, Claudia Lucía, Cerquera, Catalina, Cerquera Cleves, Catalina   +2 more
core  

Anastomotic Failure Is Not Affected by Anastomotic Technique in Minimally Invasive Two‐Stage Oesophagectomy

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The choice of anastomotic technique in minimally invasive oesophagectomy (MIO) may influence postoperative morbidity and long‐term outcomes. The primary aim of our study is to determine whether circular (CS) or linear‐stapled (LS) anastomosis is associated with anastomotic complications following MIO.
L. Vu, C. Cabalag, L. Ng, B. Choo, A. Hardley, S. Kariyawasam   +5 more
wiley   +1 more source

Roux‐en‐Y Reconstruction After Esophagectomy for Postoperative Functional Complaints: A Case Series

ANZ Journal of Surgery, EarlyView.
Functional complaints affect half of esophagectomy patients, with no standard treatment. In nine patients, Roux‐en‐Y reconstruction for obstruction, redundant conduit, and weight loss was safely performed, with one major complication and no Grade 4 out of five events. Complete symptom resolution reached 67% at 3 months and 89% at 1 year.
Donika Zogaj, Stefan H. E. M. Clermonts, Frederieke A. Dijkstra, Boudewijn van Etten, Roy J. J. Verhage, Jenneke T. H. Hamminga, Jan Willem Haveman   +6 more
wiley   +1 more source