Results 21 to 30 of about 42,305 (336)
Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]
, 1990 The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Ahnert-Hilger, G. +4 more
core +6 more sources
Toxins, 2021 Botulinum toxin type A (BoNT-A) represents a first-line treatment for spasticity, a common disabling consequence of many neurological diseases. Electrical stimulation of motor nerve endings has been reported to boost the effect of BoNT-A. To date, a wide
Alessandro Picelli +6 more
doaj +1 more source
rAAV expressing recombinant neutralizing antibody for the botulinum neurotoxin type A prophylaxis
Frontiers in Microbiology, 2022 Botulinum neurotoxin (BoNT) is one of the most dangerous bacterial toxins and a potential biological weapon component. BoNT mechanism of pathological action is based on inhibiting the release of neurotransmitters from nerve endings.
Artem A. Derkaev +9 more
doaj +1 more source
Botulinum Neurotoxin Serotypes Detected by Electrochemical Impedance Spectroscopy
Toxins, 2015 Botulinum neurotoxin is one of the deadliest biological toxins known to mankind and is able to cause the debilitating disease botulism. The rapid detection of the different serotypes of botulinum neurotoxin is essential for both diagnosis of botulism and
Alison C. Savage +3 more
doaj +1 more source
Toxins, 2020 Botulinum toxins (BoNTs) are a true wonder of nature [...]
Siro Luvisetto
doaj +1 more source
The binding of botulinum neurotoxins to different peripheral neurons [PDF]
, 2017 Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
core +1 more source
A survey of traditional Iranian food products for contamination with toxigenic Clostridium botulinum
Journal of Infection and Public Health, 2009 Summary: This study aimed to determine the rate of Clostridium botulinum contamination in some traditional Iranian food products (cheese, kashk and salted fish) and evaluate the efficacy of the mouse bioassay method in detection of C. botulinum toxins in
H.R. Tavakoli +5 more
doaj +1 more source
Applied Sciences, 2021 Botulinum toxins or neurotoxins (BoNTs) are the most potent neurotoxins known, and are currently extensively studied, not only for their potential lethality, but also for their possible therapeutic and cosmetic uses.
Massimo Corsalini +10 more
doaj +1 more source
Cost minimization analysis of BoNT-As in the treatment of upper limb spasticity and cervical dystonia [PDF]
, 2016 Botulinum toxin type A (BoNT-A) injections are recommended for the management of upper limb spasticity (ULS) and cervical dystonia (CD). The main aim of this cost minimization analysis (CMA) was to compare the annual cost per patient for three BoNT-As ...
Bartolomei, Luigi +15 more
core +1 more source
Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells
Toxins, 2020 C3 protein toxins produced by Clostridium (C.) botulinum and C. limosum are mono-ADP-ribosyltransferases, which specifically modify the GTPases Rho A/B/C in the cytosol of monocytic cells, thereby inhibiting Rho-mediated signal transduction in monocytes,
Maximilian Fellermann +12 more
doaj +1 more source