Results 61 to 70 of about 311,527 (352)

Mechanisms of Botulinum Toxin Type A Action on Pain

open access: yesToxins, 2019
Already a well-established treatment for different autonomic and movement disorders, the use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding.
I. Matak   +3 more
semanticscholar   +1 more source

Ultrasonographic assessment of the lateral pterygoid muscle for BoNT‐A injection

open access: yesClinical Anatomy, EarlyView.
Abstract The upper head of the lateral pterygoid muscle (LPM) is known to insert into the capsule of the temporomandibular joint and articular disc, and therefore its relationship with temporomandibular disorders (TMD) has been consistently suggested.
Hyungkyu Bae   +4 more
wiley   +1 more source

Dosage of botulinum toxin in patients undergoing treatment for hemifacial spasm: is there modification during follow-up?

open access: yesArquivos de Neuro-Psiquiatria
Background The movement disorder known as hemifacial spasm is characterized by involuntary contractions of the muscles that are innervated by the facial nerve. The treatment of choice for this condition is botulinum toxin injections.
Fátima de Menezes Dantas   +4 more
doaj   +1 more source

Molecular Diversity of BoNT-Producing Clostridia—A Still-Emerging and Challenging Problem

open access: yesDiversity, 2023
The diversity of BoNT-producing Clostridia is still a worrying problem for specialists who explore the evolutionary and taxonomic diversity of C. botulinum.
Tomasz Grenda   +6 more
doaj   +1 more source

Noradrenaline release from permeabilized synaptosomes is inhibited by the light chain of tetanus toxin [PDF]

open access: yes, 1992
Noradrenaline release from rat brain cortical synaptosomes permeabilized with streptolysin O can be triggered by μM concentrations of free Ca2+. This process was inhibited within minutes by tetanus toxin and its isolated light chain, but not by its heavy
Ahnert-Hilger   +35 more
core   +2 more sources

Positional Relationship Between the Orbicularis Oculi and Zygomaticus Complex Muscles by Ultrasonography: New Anatomical Insights for Crow's Feet Injection

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao   +3 more
wiley   +1 more source

Botulinum neurotoxin X lacks potency in mice and in human neurons

open access: yesmBio
Botulinum neurotoxins (BoNTs) are a class of toxins produced by Clostridium botulinum (C. botulinum) and other species of Clostridia. BoNT/X is a putative novel botulinum neurotoxin identified through genome sequencing and capable of SNARE cleavage, but ...
Brieana M. Gregg   +8 more
doaj   +1 more source

Novel Botulinum Neurotoxins: Exploring Underneath the Iceberg Tip

open access: yesToxins, 2018
Botulinum neurotoxins (BoNTs), the etiological agents of botulism, are the deadliest toxins known to humans. Yet, thanks to their biological and toxicological features, BoNTs have become sophisticated tools to study neuronal physiology and valuable ...
Domenico Azarnia Tehran, Marco Pirazzini
doaj   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

A survey of traditional Iranian food products for contamination with toxigenic Clostridium botulinum

open access: yesJournal of Infection and Public Health, 2009
Summary: This study aimed to determine the rate of Clostridium botulinum contamination in some traditional Iranian food products (cheese, kashk and salted fish) and evaluate the efficacy of the mouse bioassay method in detection of C. botulinum toxins in
H.R. Tavakoli   +5 more
doaj  

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