Botulinum toxin therapy: functional silencing of salivary disorders. [PDF]
, 2017 Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary ...
Lovato, A +4 more
core
A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]
, 2020 Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan +4 more
core
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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Enzyme-linked immunosorbent assay for detection of Clostridium botulinum toxin type A.
Japanese Journal of Medical Science & Biology, 1978 The enzyme linked immunosorbent assay using the so-called "double-sandwich technique" has been applied to determine botulinum toxin type A. By this assay, 50-100 mouse ip LD50 of toxin type A can be detected.
S. Notermans, J. Dufrenne, M. Schothorst
semanticscholar +1 more source
Recombinant production of bacterial toxins and their derivatives in the methylotrophic yeast Pichia pastoris. [PDF]
, 2005 RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Ellar, David J, Gurkan, Cemal
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Arquivos de Neuro-PsiquiatriaMotor impairments in stroke survivors are prevalent and contribute to dependence in daily activities, pain and overall disability, which can further upper-limb disability.
André Luiz Salcedo Gomes +5 more
doaj +1 more source
Botulinum toxin type-A in the treatment of glabellar lines
Clinical, Cosmetic and Investigational Dermatology, 2009 The current literature and state of the art on use of botulinum toxin type-A in the treatment of glabellar rhytids was reviewed. Botulinum toxin type-A is a safe and effective way to manage glabellar rhytids. Mastery of the anatomy of the glabellar region, familiarity with the products currently available on the market and judicious dosing results in ...
Jeffrey H. Spiegel, Leslie K. Winter
openaire +5 more sources
Structure of dual receptor binding to botulinum neurotoxin B [PDF]
, 2014 Botulinum neurotoxins are highly toxic, and bind two receptors to achieve their high affinity and specificity for neurons. Here we present the first structure of a botulinum neurotoxin bound to both its receptors.
Berntsson, Ronnie P-A +3 more
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Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains. [PDF]
, 2016 Clostridium sporogenes is a non-pathogenic close relative and surrogate for Group I (proteolytic) neurotoxin-producing Clostridium botulinum strains.
Bullough, Per A. +7 more
core +2 more sources
Kinetics of the Thermal Inactivation of Type E Clostridium botulinum Toxin [PDF]
, 1967 J. J. Licciardello +3 more
openalex +1 more source