Results 61 to 70 of about 16,559 (199)

SNARE based peptide linking as an efficient strategy to retarget botulinum neurotoxin’s enzymatic domain to specific neurons using diverse neuropeptides as targeting domains [PDF]

open access: yes, 2011
Many disease states are caused by miss-regulated neurotransmission. A small fraction of these diseases can currently be treated with botulinum neurotoxin type A (BoNT/A).
,   +6 more
core  

Measuring What Matters in Parkinson's Disease Research and Dysphagia: The Need for Core Outcome Sets

open access: yes
Movement Disorders, EarlyView.
Margaret Walshe   +2 more
wiley   +1 more source

Comparison of the effects of occlusal splint and Botox injections on the amount of mouth opening and chronic pain in individuals with temporomandibular disorders: a systematic review and meta‐analysis

open access: yesAustralian Dental Journal, EarlyView.
Abstract Objective This systematic review and meta‐analysis study was carried out to compare the effectiveness of occlusal splint (OS) and Botox (BTX) injections in temporomandibular disorders (TMDs). Material and Methods Irrespective of the starting year, studies were searched for up to 2024 using PubMed, Web of Science, Scopus databases and the ...
Ö İşisağ, H Atasoy, S Yıldız
wiley   +1 more source

Botulinum toxin therapy: functional silencing of salivary disorders. [PDF]

open access: yes, 2017
Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary ...
Lovato, A   +4 more
core  

A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]

open access: yes, 2020
Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan   +4 more
core  

Botulinum toxin type A in motor nervous system: unexplained observations and new challenges [PDF]

open access: yes, 2016
In the motor system, botulinum toxin type A (BoNT/A) actions were classically attributed to its well-known peripheral anticholinergic actions in neuromuscular junctions.
Lacković, Zdravko   +2 more
core   +1 more source

Dorsal Genital Nerve Stimulation as an Adjunctive Therapy to Control Neurogenic Detrusor Overactivity After Spinal Cord Injury

open access: yesArtificial Organs, EarlyView.
People with spinal cord injury (SCI) experience bladder overactivity, which can cause incontinence. Dorsal genital nerve stimulation (DGNS) can suppress overactivity, providing a longer duration to reach a toilet. People with SCI trialed home‐based DGNS for 8 weeks. DGNS was effective in the laboratory, and participants found home‐based DGNS acceptable.
Sean Doherty   +4 more
wiley   +1 more source

Neurotoxicity [PDF]

open access: yes, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust   +15 more
core   +2 more sources

Botulinum toxin type-A in the treatment of glabellar lines

open access: yesClinical, Cosmetic and Investigational Dermatology, 2009
The current literature and state of the art on use of botulinum toxin type-A in the treatment of glabellar rhytids was reviewed. Botulinum toxin type-A is a safe and effective way to manage glabellar rhytids. Mastery of the anatomy of the glabellar region, familiarity with the products currently available on the market and judicious dosing results in ...
Jeffrey H. Spiegel, Leslie K. Winter
openaire   +5 more sources

Long‐term urinary outcomes in classic bladder exstrophy: results of an extensive follow‐up

open access: yesBJU International, Volume 135, Issue 6, Page 1018-1024, June 2025.
Objectives To evaluate long‐term outcomes and predictive factors of urinary continence (UC) and fecal continence (FC) after surgery for classic bladder exstrophy (CBE) using validated questionnaires. Patients and Methods This study is part of the QUALEXSTRO study, a retrospective, observational, single‐centre cohort study assessing through ...
Sarah Abdellaoui   +7 more
wiley   +1 more source

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