Results 31 to 40 of about 24,446 (243)
The binding of botulinum neurotoxins to different peripheral neurons [PDF]
, 2017 Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
core +1 more source
Human and animal botulism surveillance in France from 2008 to 2019
Frontiers in Public Health, 2022 Botulism is a human and animal neurological disease caused by the action of bacterial neurotoxins (botulinum toxins) produced by bacteria from the genus Clostridium.
Sophie Le Bouquin +10 more
doaj +1 more source
Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
, 1979 Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin +2 more
core +1 more source
Foodborne Botulism in the Republic of Georgia
Emerging Infectious Diseases, 2004 Foodborne botulism is a potentially fatal, paralytic illness that can cause large outbreaks. A possible increase in botulism incidence during 2001 in Georgia prompted this study.
Jay K. Varma +12 more
doaj +1 more source
Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]
, 1977 The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner +19 more
core +1 more source
Exploring the genetic background of the botulism neurotoxin BoNT/B2 in Spain
Microbiology Spectrum, 2023 To determine whether the neurotoxin BoNT/B2 causing botulism in Spain is clonal, the genetic diversity and phylogenetic relationships of Clostridium botulinum from food-borne episodes and infant cases of the condition were explored.
Sylvia Valdezate +7 more
doaj +1 more source
Botulism in the 21st Century: A Scoping Review
Brown Journal of Hospital Medicine, 2023 Botulism is a potentially deadly neuroparalytic disease that affects all age groups; it is highly challenging to diagnose due to its nonspecific symptoms. Infant botulism is the most common form of botulism in the United States, followed by foodborne and
Ketino Kobaidze, Zanthia Wiley
doaj
Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. [PDF]
, 2016 BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires ...
Arnon, Stephen S +5 more
core +1 more source
Local outbreak of foodborne botulism in Krasnoyarsk
Детские инфекции (Москва), 2023 Botulism is a serious infectious disease that has not lost its relevance today. Due to the widespread popularity of home canning, botulism is widespread everywhere, more often recorded in the form of sporadic cases and small (local) outbreaks.
G. P. Martynova +7 more
doaj +1 more source
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2018 The cholinergic heat-labile neurotoxin produced by Clostridium species is primarily responsible for the clinical manifestations of botulism. The classic phenotypic presentation of botulism consists of subacute descending flaccid paralysis with intact ...
Pramod K. Guru, MBBS, MD +6 more
doaj +1 more source