Results 31 to 40 of about 16,499 (205)

Symptomatic treatment of botulism with a clinically approved small molecule.

JCI Insight, 2020
Botulinum neurotoxins (BoNTs) are potent neuroparalytic toxins that cause mortality through respiratory paralysis. The approved medical countermeasure for BoNT poisoning is infusion of antitoxin immunoglobulins.
Edwin J. Vazquez-Cintron, James B. Machamer, Celinia A. Ondeck, Kathleen T. Pagarigan, B. Winner, Paige M. Bodner, Kyle E. Kelly, M. Pennington, P. McNutt   +8 more
semanticscholar   +1 more source

Infant Botulism

Journal of education & teaching in emergency medicine, 2023
This oral board case is appropriate for emergency medicine residents and medical students (with senior resident assistance) on emergency medicine rotation.Although a somewhat rare disease, infant botulism is a true pediatric emergency that carried a 90% rate of mortality prior to the development of an antitoxin.1 While botulism infections can be ...
Garispe, DO, Ashley, Cherry, MD, Steven
openaire   +3 more sources

Foodborne Botulism Outbreak Associated with Commercial Nacho Cheese Sauce from a Gas Station Market.

Clinical Infectious Diseases, 2020
BACKGROUND Botulism is a rare and potentially fatal paralytic disease caused by botulinum neurotoxin (BoNT). In April 2017, four California residents, from two adjacent counties, were hospitalized with suspected foodborne botulism, precipitating an ...
H. Rosen, A. Kimura, John Crandall, A. Poe, J. Nash, Jason Boetzer, S. Tecle, Rituparna Mukhopadhyay, Kate McAuley, Olivia Kasirye, A. Garza, M. Shahkarami, V. Chaturvedi, D. Kiang, J. Vidanes, K. McCoy, Mark Barcellos, Tammy Derby, Seemalata Jain, D. Vugia   +19 more
semanticscholar   +1 more source

Public Health Risk Associated with Botulism as Foodborne Zoonoses

Toxins, 2019
Botulism is a rare but severe neurological disease in man and animals that is caused by botulinum neurotoxins (BoNTs) produced by Clostridium botulinum and atypical strains from other Clostridium and non-Clostridium species.
C. Rasetti-Escargueil, E. Lemichez, M. Popoff   +2 more
semanticscholar   +1 more source

Modification and validation of the Endopep-mass spectrometry method for botulinum neurotoxin detection in liver samples with application to samples collected during animal botulism outbreaks

Analytical and Bioanalytical Chemistry, 2020
Botulinum neurotoxins (BoNTs) are the most potent toxins known and they cause the paralytic disease botulism in humans and animals. In order to diagnose botulism, active BoNT must be detected in biological material.
Annica Tevell Åberg, I. Karlsson, M. Hedeland   +2 more
semanticscholar   +1 more source

Development of An Innovative and Quick Method for the Isolation of Clostridium botulinum Strains Involved in Avian Botulism Outbreaks

Toxins, 2020
Avian botulism is a serious neuroparalytic disease mainly caused by a type C/D botulinum neurotoxin produced by Clostridium botulinum group III, one of the entwined bacterial species from the Clostridium novyi sensu lato genospecies.
T. Le Gratiet, T. Poezevara, S. Rouxel, E. Houard, C. Mazuet, M. Chemaly, C. Le Maréchal   +6 more
semanticscholar   +1 more source

Prevalence, Risk Factors, and Epidemiology of Food-borne Botulism in Iran

Journal of Epidemiology and Global Health, 2020
Background: Botulism is a severe neuroparalytic disease caused by toxins produced by several Clostridium species. This work presents the surveillance results of botulism in Iran, with the distribution of the cases by regions and by vehicle of ...
Mohammad Reza Montazer Khorasan, M. Rahbar, Abed Zahedi Bialvaei, M. Gouya, F. Shahcheraghi, B. Eshrati   +5 more
semanticscholar   +1 more source

Infant botulism.

Annali dell'Istituto Superiore di Sanità, 2020
Infant botulism is a rare disease that affects infant less than 12 months of age. The illness results from absorption of botulinum toxin produced in situ by neurotoxigenic clostridia that can temporarily colonize the intestinal tract of infants. To date,
L. Fenicia, F. Anniballi
semanticscholar   +1 more source

Aptamer and DNAzyme Based Colorimetric Biosensors for Pathogen Detection

Angewandte Chemie, Volume 137, Issue 4, January 21, 2025.
Pathogen detection is crucial for preventing and managing health risks. This review consolidates the selection of functional nucleic acids (FNAs) for pathogen detection and the development of cost‐effective, simple diagnostic applications. It focuses on integrating FNAs with gold nanoparticles, polydiacetylenes, protein enzymes, G‐quadruplexes, and ...
Rudi Liu, Jiuxing Li, Bruno J. Salena, Yingfu Li   +3 more
wiley   +2 more sources

Engaging South Asian Communities in the United Kingdom to Explore Infant Feeding Practices and Inform Intervention Development: Application of the REPLACE Approach

Maternal &Child Nutrition, EarlyView.
The LIFT project provides valuable insight into infant feeding practices of Bangladeshi and Pakistani communities in the United Kingdom. It identifies the communities' perspective on which infant feeding practices should be a priority and which are most amenable to change, offering a robust evidence base to draw on in the development of culturally ...
Kayleigh Kwah, Maxine Sharps, Naomi Bartle, Kubra Choudhry, Jacqueline Blissett, Katherine Brown   +5 more
wiley   +1 more source