Results 41 to 50 of about 12,381 (221)

Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison

Acta Crystallographica Section F, Volume 82, Issue 11, Page 391-401, November 2026.
For the first time, the recombinant core botulinum neurotoxin type A (BoNT/A) expressed in Escherichia coli and nicked in vitro is shown to be structurally identical to native BoNT/A from Clostridium botulinum, enabling direct activity comparison between the recombinant product and the native toxin.Botulinum neurotoxins (BoNTs) are highly potent ...
Zongren Yao, Lingyi Xu, Yu Lu, Hui Gong, Xiaoyun Sun, Yaokun Zhao, Jinhuan Chen, Liming Yang, Qingqing Chen, Wu Yang   +9 more
wiley   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, Volume 6, Issue 10, Page 392-421, October 2026.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

Survival of Listeria monocytogenes and Salmonella Typhimurium in Pepperoni With Reduced Salt and Sodium Nitrite Levels, and Sublethal Thermal Treatments

Journal of Food Safety, Volume 46, Issue 5, October 2026.
Reduced salt and sodium nitrite pepperoni formulations were challenged with Listeria monocytogenes and Salmonella Typhimurium and subjected to fermentation followed by a postfermentation thermal treatment and drying. Enhanced thermal treatments improved pathogen reductions across formulations, supporting the importance of validated multihurdle ...
Shannon Heapes, Victoria Caballero, Jesus Frias, Bradley Afanda, Martin Danaher, Joseph P. Kerry, Geraldine Duffy   +6 more
wiley   +1 more source

Pragmatic Phenotype–Electrophysiology–Genomics Integration in Pediatric Congenital Myasthenic Syndromes: Insights From 36 Patients in a Single‐Center Study in China

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
In 36 Chinese pediatric CMS patients, integrated phenotype, RNS, and genomic assessment revealed marked genetic heterogeneity across 17 CMS‐associated genes and frequent VUS‐related uncertainty. Genotype‐informed therapy improved MG‐ADL scores, while CHAT‐CMS identified a high‐risk subgroup for early respiratory failure and mortality.
Liya Cui, Kaiyue Ma, Xiaona Fu, Lin Ge, Bingbing Jia, Wenna Ma, Lei Yang, Zhimei Liu, Junlan Lv, Wenmiao Xu, Lijuan Wang, Guangyuan Zhao, Jiuwei Li, Jie Wu, Quan Wang, Changhong Ding, Xiaotun Ren, Xinming Shen, Hui Xiong   +18 more
wiley   +1 more source

Feathers and flu: identifying data gaps in avian influenza host dynamics to prioritize wildlife conservation Plumas y gripe: identificación de datos faltantes en la dinámica de hospedadores de la influenza aviar para priorizar la conservación de la vida silvestre

Wildlife Monographs, Volume 225, Issue 1, September 2026.
We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey, Matthew Gonnerman, Shenglai Yin, Cody M. Kent, Joshua Cullen, Jeffery D. Sullivan, Jonathan B. Dain, Nichola J. Hill, Diann J. Prosser, Jennifer M. Mullinax   +9 more
wiley   +1 more source

Healthcare workers’ knowledge and preparedness for unprecedented foodborne botulism outbreak in Saudi Arabia

Journal of Infection and Public Health
Background: The recent unprecedented foodborne botulism outbreak in Saudi Arabia necessitated an assessment of healthcare workers' (HCWs) knowledge, attitudes, and practices (KAP).
Abdullah Alhuzaimi, Fatimah S. Alshahrani, Fadi Aljamaan, Fatema H. AL-Ajwad, Ibraheem Altamimi, Abdullah Bukhari, Lama Al-Eyadhy, Sarah Al-Subaie, Nasser S. Alharbi, Mazin Barry, Yamen Shayah, Amr Jamal, Alaa A. Alanteet, Khalid Alhasan, Sameera M. Aljuhani, Jaffar A. Al-Tawfiq, Mohamad-Hani Temsah   +16 more
doaj   +1 more source

Botulism with Unusual Rapid Progression to Complete Paralysis in a Child

Pediatrics and Neonatology, 2015
Botulism is a severe neuroparalytic illness which is difficult to diagnose accurately, especially in children. We report a child with type A botulism intoxication, with very rapid progression to coma-like consciousness and respiratory failure.
Hui-Ju Tsai, Wen-Chen Liang, Chien-Hua Wang, Po-Ching Chou, Jong-Hau Hsu, Chia-Tsuan Huang, Yuh-Jyh Jong   +6 more
doaj   +1 more source

Feasibility and Safety of Washed Microbiota Transplantation as Salvage Therapy for Refractory Non‐CDI Gut Pathogens in Critically Ill Patients

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Ten patients with definite gut infection evidence beyond CDI underwent 29 WMT infusions. 50% (5/10) of patients obtained clinical cure after WMT. 20% (2/10) of patients achieved clinical improvement and 30% (3/10) showed no response 7 days after WMT. One transient WMT‐related fever occurred (1/29, 3.45%).
Jie Xu, Aoli Diao, Rujun Ai, Xia Wu, Quan Wen, Yuyan Xiao, Xinyi He, You Yu, Zulun Zhang, Yeqing Wang, Zhihua Zhang, Faming Zhang, Bota Cui   +12 more
wiley   +1 more source

Four Cases of Food-Borne Botulism in a Family

پزشکی بالینی ابن سینا, 2002
Botulism is caused  by a neurotoxin produced from the anaerobic,    Spore-forming bacterium clostridium botulinum. Botulism have four     clinical  forms:1)Food –borne botulism   2)Wound botulism    3)Infant botulism    4)undetermined botulism, that the 
Fariba Keramat
doaj  

A rare symptom of foodborne botulism: dysgeusia. Case report and clinical review

Emergency Care Journal
Clostridium botulinum has become one of the most well-known microorganisms in medical history, thanks to both fatal botulism epidemics and the recent medical use of botulinum neurotoxin.
Simone Esposito, Francesco Coletta, Giovanna Di Maiolo, Filomena Lo Chiatto, Pasquale Rinaldi, Anna Lanza, Getano Panico, Crescenzo Sala, Antonio Tomasello, Romolo Villani   +9 more
doaj   +1 more source