Results 91 to 100 of about 181,461 (268)
Studying boundary elements’ behaviour using masonry walls built with high-resistance bricks
Ingeniería e Investigación, 2006 This research was aimed at studying the behaviour of masonry walls built with and without boundary elements at both ends when sublected to monotonic and cyclic lateral loads.
Juan Carlos Restrepo Mejía +1 more
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
APPLYING BOUNDARY ELEMENT METHOD TO SOLVE THE HEAT CONDUCTION PROBLEMS USING CONSTANT ELEMENT
Journal of Engineering and Sustainable Development, 2015 In this work two-dimensional boundary element method (BEM) using constant element is mathematically and numerically investigated and applied to solve differential equations of the heat conduction problems and temperature distribution of solid bodies to ...
Saad Najeeb Shehab
doaj
Hybrid stress and analytical functions for analysis of thin plates bending
Latin American Journal of Solids and StructuresIn this paper, two efficient elements for analyzing thin plate bending are proposed. They are a triangular element (THS) and a quadrilateral element (QHS), which have 9 and 12 degrees of freedom, respectively.
Mohammad Rezaiee-Pajand, Mohammad Karkon
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Integrity of a heterochromatic domain ensured by its boundary elements. [PDF]
Proc Natl Acad Sci U S A, 2020 Charlton SJ, Jørgensen MM, Thon G.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Precise boundary element method for non-horizontally layered foundations and its applications
Yantu gongcheng xuebaoA new boundary element method (BEM) is developed for accurately calculating the additional stresses and settlements in non-horizontally layered foundations.
XIAO Sha 1 , YUE Zhongqi 2, 3
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source