The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Retraction notice to "Analysis of Conocurvone, Ganoderic acid A and Oleuropein molecules against the main protease molecule of COVID-19 by in silico approaches: Molecular dynamics docking studies" [Engineering Analysis with Boundary Elements volume 150 (2023) Pages 583-598]. [PDF]
Eng Anal Bound Elem, 2023 Le QH +7 more
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Techniques to accelerate boundary element contributions in elasticity [PDF]
, 2007 The problem of rapid re-analysis of small problems in elasticity is investigated. The aim is to enable updated stress contours to be displayed in real-time as a design geometry is dynamically modified.
Scales, Derek
core
Some remarks on the applicability of rectangular elements to plane strain boundary value problems
Computer Assisted Methods in Engineering and Science, 2023 The aim of this paper is the discussion on the applicability of some rectangular elements to plane strain boundary value problems. Four different elements were considered: 4-node, 5-node, Serendipity 8-node and Lagrangian 9-node. Two cases: the material
Andrzej Jarzębowski, Jan Maciejewski
doaj
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Numerical solution and spectrum of boundary-domain integral equation for the Neumann BVP with variable coefficient [PDF]
, 2012 This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Taylor & Francis.In this paper, a numerical implementation of a direct united boundary-domain integral equation (BDIE ...
Mikhailov, SE, Mohamed, NA
core +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The stress analysis of frictional punch with crack in plane elasticity using boundary element method [PDF]
, 2000 22nd International Conference on the Boundary Element Method (BEM XXII) -- SEP 04-06, 2000 -- CAMBRIDGE UNIV, NEW HALL COLL, CAMBRIDGE, ENGLANDIn this paper boundary element (BE) formulations for contact and fracture problems are briefly reviewed and the
Gun, H
core +1 more source